Department of Pathology and Laboratory Medicine

Penn Medicine’s Department of Pathology and Laboratory Medicine is one of the leading, fully integrated academic departments and is organized into a number of clinical divisions: Anatomic Pathology, Neuropathology, Laboratory Medicine, Transfusion Medicine and Therapeutic Pathology, Hematopathology, Precision and Computational Diagnostics, Pediatric Pathology, and its basic science division, Experimental Pathology and Immunobiology. As part of the nation's first medical school, founded in 1765, the Department of Pathology and Laboratory Medicine traces its origins to 1895 when the William Pepper Laboratory of Clinical Medicine, the nation’s first fully equipped laboratory for routine and investigative work, was founded.


  • Department consistently ranks among the top three in the nation in NIH funding and was ranked #1 in NIH awards for 2014
  • Research strengths include neurodegenerative diseases, immunobiology, cancer biology and therapeutics, cardiovascular pathobiology, and HIV immunology
  • Preeminent pathology and laboratory medicine residency training programs and major faculty role in training MD/PhD students and graduate students through the Perelman School of Medicine Biomedical Graduate Studies Groups
  • One of two hospital-based departments in the Perelman School of Medicine at the University of Pennsylvania with a primary focus on clinical diagnostics, performing 10 million diagnostic tests annually
  • At the forefront for infusional therapeutics and next-generation therapeutics, including immunotherapy and precision medicine diagnostics
  • Provides many of the Perelman School of Medicine’s centralized resource laboratories, while faculty maintains substantive ties to multiple centers, institutes, departments, and other schools at Penn
  • Encompasses a range of clinical operations in hospitals that are part of Penn Medicine or facilities affiliated with Penn Medicine hospitals, including the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Pennsylvania Hospital (the nation’s first hospital, founded in 1751), and The Children’s Hospital of Philadelphia


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