Paul H. Edelstein, MD

Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
University of Pennsylvania Perelman School of Medicine
Director, Clinical Microbiology Laboratory

Contact InformationHUP - 4 Gates
3400 Spruce St
Philadelphia, PA 19104
Office: 215-662-6651


Specialty Division

Laboratory Medicine

Itmat Expertise

Novel tuberculosis treatment, healthcare associated infections, novel laboratory diagnostics.


no degree (Chemistry major), San Jose State College, San Jose, California, 1969
M.D. (medicine), University of California at Los Angeles, 1973

Specialty Certification

National Board of Medical Examiners #131761, 1973
American Board of Internal Medicine #055675 in Internal Medicine, 1976
American Board of Internal Medicine #055675 in Infectious Diseases, 1978
Diplomat of American Board of Medical Microbiology in Public Health and Medical and Molecular Microbiology, 1985

Postgraduate Training

Intern in Internal Medicine, Wadsworth VA Medical Center, 1973-1974
Resident in Internal Medicine, Wadsworth VA Medical Center, 1974-1976
Fellow in Infectious Diseases, Wadsworth VA Medical Center, 1976-1978
Chief Medical Resident, Wadsworth VA Medical Center, 1977-1978

Awards and Honors

National Science Foundation Fellowship in Physical Chemistry Research, 1967-1969
Elected member of Phi Kappa Phi, National Scientific Fraternity, 1969
Burroughs-Wellcome Traveling Fellowship to Great Britain, 1981
Japan Society for the Promotion of Science Scholar Traveling Fellowship to Japan, 1982
Lowbury Lecturer, Hospital Infection Society of Britain, London, 1985
W. G. Smith Memorial Lecturer, University of Western Australia Medical School, 1989

Memberships and Professional Organizations

Clinical Laboratory Standards Institute, 2014 - Present
British Medical Research Council, 2015 - 2016
American Society for Microbiology, - Present
American Thoracic Society, - Present
American Thoracic Society, - Present
Infectious Diseases Society of America, - Present
Infectious Diseases Society of America, - Present
British Society for Antimicrobial Chemotherapy, - Present
American Academy of Microbiology, - Present
American College of Physicians, - Present
American Chemical Society, - Present
American Federation for Clinical Research, - Present

Web Links

Selected Publications

In vitro and intracellular activities of LBM415 (NVP PDF-713) against Legionella pneumophila.

Edelstein PH, Hu B, Edelstein MAC, Antimicrob Agents Chemother 49(): in press, 2005, PMID:15917565

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Legionnaires Disease, Pontiac Fever, and Related Illnesses.

Edelstein PH., Pediatric Infectious Diseases, 5th edition, 2004

Legionella maceachernii pneumonia in a patient with HIV infection

Dumoff K, McGovern PC, Edelstein PH, Nachmakin I., Diag Microbiol Infect Dis 50(): 141-145, 2004, PMID:15474325

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Activities of tigecycline (GAR-936) against Legionella pneumophila in vitro and in guinea pigs with L. pneumophila pneumonia.

Edelstein PH, Weiss WJ, Edelstein MAC., Antimicrob Agents Chemother 47(): 533-540, 2003, PMID:12543655

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lvgA, a novel Legionella pneumophila virulence factor.

Edelstein PH, Hu B, Higa F, Edelstein MAC., Infect Immun 71(): 2394-2403, 2003, PMID:12704109

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A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila.

Brassinga AK, Hiltz MF, Sisson GR, Morash MG, Hill N, Garduno E, Edelstein PH, Garduno RA, Hoffman PS, J. Bacteriol 185(): 4630-4637, 2003, PMID:12867476

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Risk factors for fluoroquinolone resistance in nosocomial Escherichia coli and Klebsiella pneumoniae infections.

Lautenbach E, Fishman NO, Bilker WB, Castiglioni A, Metlay J, Edelstein PH, Strom BL., Arch Intern Med 162(): 2469-2477, 2002, PMID:12437407

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Detection of Antibodies to Legionella.

Edelstein PH., Manual of Clinical Laboratory Immunology, 6th edition, 2002

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