Jennifer J.D. Morrissette, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine
Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817
Email: jennifer.morrissette@uphs.upenn.edu
Specialty Division
Precision and Computational Diagnostics
Education
B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992
Specialty Certification
American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004
Postgraduate Training
Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002
Awards and Honors
Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013
Memberships and Professional Organizations
American Society Human Genetics, 1998 - Present
Philadelphia Genetics Group, 2004 - 2018
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Association of Molecular Pathology, 2011 - Present
American Society for Clinical Pathology (ASCP) Immuno-Oncology Working Group, 2018 - Present
International Federation of Clinical Chemistry and Laboratory Medicine, 2019 - Present
Web Links
Selected Publications
Clinical Activity of the EGFR Tyrosine Kinase Inhibitor Osimertinib in EGFR-mutant Glioblastoma
Makhlin I, Salinas RD, Zhang D, Jacob F, Ming G-L, Song H, Saxena D, Dorsey JF, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Desai AS, Brem S, Bagley SJ, CNS Oncol., 2019, PMID:31769726
Negative prognostic impact of epidermal growth factor receptor copy number gain in young adults with isocitrate dehydrogenase wild-type glioblastoma.
Hoffman Daniel I, Abdullah Kalil G, McCoskey Makayla, Binder Zev A, O'Rourke Donald M, Desai Arati S, Nasrallah MacLean P, Bigdeli Ashkan, Morrissette Jennifer J D, Brem Steven, Bagley Stephen J, Journal of neuro-oncology 145(2): 321-328, 2019, PMID:31542863
Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study
Bagley SJ, Nabavizadeh SA, Mays JJ, Till JE, Ware JB, Levy S, Sarchiapone W, Hussain J, Prior T, Guiry S, Christensen T, Yee SS, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Cucchiara AJ, Brem S, Desai AS, Carpenter EL., Clinical Cancer Research, 2019
Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study.
Bagley Stephen J, Nabavizadeh S Ali, Mays Jazmine J, Till Jacob E, Ware Jeffrey B, Levy Scott, Sarchiapone Whitney, Hussain Jasmin, Prior Timothy, Guiry Samantha, Christensen Theresa, Yee Stephanie S, Nasrallah MacLean P, Morrissette Jennifer J D, Binder Zev A, O'Rourke Donald M, Cucchiara Andrew J, Brem Steven, Desai Arati S, Carpenter Erica L, Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, PMID:31666247
Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia
Velu, PD, Perl, AE, Luger, SM, Bagg, A, Morrissette, JJD, British Journal of Haematology 186(6): 801, 2019
Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia.
Velu Priya D, Perl Alexander E, Luger Selina M, Bagg Adam, Morrissette Jennifer J D, British journal of haematology 186(6): 801, 2019, PMID:31206598
Understanding the Tumor Micro-Environment
Jennifer Morrissette, Jonathan Belman, Andrew Rech, ASCP News Archive, 2019
Identification and Confirmation of Potentially Actionable Germline Mutations in Tumor-Only Genomic Sequencing
Dana Farengo Clark, Kara N. Maxwell, Jacquelyn Powers, David B. Lieberman, Jessica Ebrahimzadeh, Jessica M. Long, Danielle McKenna, Payal Shah, Angela Bradbury, Jennifer J.D. Morrissette, Katherine L. Nathanson, and Susan M. Domchek, JCO Precision Oncology 2019(3): 1-11, 2019
Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia
McMahon Christine M, Ferng Timothy, Canaani Jonathan, Wang Eunice S, Morrissette Jennifer J D, Eastburn Dennis J, Pellegrino Maurizio, Durruthy-Durruthy Robert, Watt Christopher D, Asthana Saurabh, Lasater Elisabeth A, DeFilippis RosaAnna, Peretz Cheryl A C, McGary Lisa H F, Deihimi Safoora, Logan Aaron C, Luger Selina M, Shah Neil P, Carroll Martin, Smith Catherine C, Perl Alexander E, Cancer Discovery 9(8): 1050-1063, 2019, PMID:31088841
Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer
Kraya Adam A, Maxwell Kara N, Wubbenhorst Bradley, Wenz Brandon M, Pluta John, Rech Andrew J, Dorfman Liza M, Lunceford Nicole, Barrett Amanda, Mitra Nandita, Morrissette Jennifer J D, Feldman Michael, Nayak Anupma, Domchek Susan M, Vonderheide Robert H, Nathanson Katherine L, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 25(14): 4363-4374, 2019, PMID:30914433
