Jennifer J.D. Morrissette, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine
Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817
Email: jennifer.morrissette@uphs.upenn.edu
Specialty Division
Precision and Computational Diagnostics
Education
B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992
Specialty Certification
American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004
Postgraduate Training
Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002
Awards and Honors
Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013
Memberships and Professional Organizations
American Society Human Genetics, 1998 - Present
Philadelphia Genetics Group, 2004 - 2018
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Association of Molecular Pathology, 2011 - Present
American Society for Clinical Pathology (ASCP) Immuno-Oncology Working Group, 2018 - Present
International Federation of Clinical Chemistry and Laboratory Medicine, 2019 - Present
Web Links
Selected Publications
Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia
Velu, PD, Perl, AE, Luger, SM, Bagg, A, Morrissette, JJD, British Journal of Haematology 186(6): 801, 2019
Understanding the Tumor Micro-Environment
Jennifer Morrissette, Jonathan Belman, Andrew Rech, ASCP News Archive, 2019
Identification and Confirmation of Potentially Actionable Germline Mutations in Tumor-Only Genomic Sequencing
Dana Farengo Clark, Kara N. Maxwell, Jacquelyn Powers, David B. Lieberman, Jessica Ebrahimzadeh, Jessica M. Long, Danielle McKenna, Payal Shah, Angela Bradbury, Jennifer J.D. Morrissette, Katherine L. Nathanson, and Susan M. Domchek, JCO Precision Oncology 2019(3): 1-11, 2019
Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia
McMahon Christine M, Ferng Timothy, Canaani Jonathan, Wang Eunice S, Morrissette Jennifer J D, Eastburn Dennis J, Pellegrino Maurizio, Durruthy-Durruthy Robert, Watt Christopher D, Asthana Saurabh, Lasater Elisabeth A, DeFilippis RosaAnna, Peretz Cheryl A C, McGary Lisa H F, Deihimi Safoora, Logan Aaron C, Luger Selina M, Shah Neil P, Carroll Martin, Smith Catherine C, Perl Alexander E, Cancer Discovery 9(8): 1050-1063, 2019, PMID:31088841
Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer
Kraya Adam A, Maxwell Kara N, Wubbenhorst Bradley, Wenz Brandon M, Pluta John, Rech Andrew J, Dorfman Liza M, Lunceford Nicole, Barrett Amanda, Mitra Nandita, Morrissette Jennifer J D, Feldman Michael, Nayak Anupma, Domchek Susan M, Vonderheide Robert H, Nathanson Katherine L, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 25(14): 4363-4374, 2019, PMID:30914433
Clinically Determined Fusions in Gliomas: An Institutional Experience with a Fusion Transcript Panel
Nasrallah, M, Bagley, S, Desai, A, Sussman, R, Morrissette, J, Journal of Neuropathology and Experimental Neurology 78(6): 529, 2019
Validation of a Next-Generation Sequencing Assay Targeting RNA for the Multiplexed Detection of Fusion Transcripts and Oncogenic Isoforms
Sussman Robyn T, Oran Amanda R, Paolillo Carmela, Lieberman David, Morrissette Jennifer J D, Rosenbaum Jason N, Archives of Pathology & Laboratory Medicine, 2019, PMID:31211614
Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
Nasrallah, MP, Binder, ZA, Oldridge, DA, Zhao, J, Lieberman, DB, Roth, JJ, Watt, CD, Sukhadia, S, Klinman, E, Daber, RD, Desai, A, Brem, S, O'Rourke, DM, Morrissette, JJD, Academic Pathology 6(): , 2019
Gilteritinib induces differentiation in relapsed and refractory -mutated acute myeloid leukemia
McMahon Christine M, Canaani Jonathan, Rea Bryan, Sargent Rachel L, Qualtieri Julianne N, Watt Christopher D, Morrissette Jennifer J D, Carroll Martin, Perl Alexander E, Blood Advances 3(10): 1581-1585, 2019, PMID:31122910
FBXW7 mutations in acute myeloid leukemia
Sadigh, S, Morrissette, JJD, Bagg, A, Leukemia & Lymphoma 60(6): 1601-1602, 2019
