PEOPLE

Jennifer J.D. Morrissette, PhD

Assistant Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine

Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817

Email: jennifer.morrissette@uphs.upenn.edu

Specialty Division

Precision and Computational Diagnostics

Education

B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992

Specialty Certification

American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004

Postgraduate Training

Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002

Awards and Honors

Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013

Memberships and Professional Organizations

American Society Human Genetics, 1998 - Present
Philadelphia Genetics Group, 2004 - Present
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Association of Molecular Pathology, 2011 - Present

Web Links


Selected Publications

Marginal zone lymphoma-derived interfollicular diffuse large B-cell lymphoma harboring 20q12 chromosomal deletion and missense mutation of BIRC3 gene: a case report.

Hatem Joseph, Schrank-Hacker April M, Watt Christopher D, Morrissette Jennifer J D, Rubin Adam I, Kim Ellen J, Nasta Sunita D, Wasik Mariusz A, Bogusz Agata M, Diagnostic pathology 11(1): 137, 2016, PMID:27993143

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Utilization of next generation sequencing identifies potentially actionable mutations in chronic lymphocytic leukaemia.

Wang J, Morrissette J, Lieberman DB, Timlin C, Schuster SJ, Mato AR., Br J Haematol., 2016, PMID:27714764

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Clinicopathogenomic analysis of mismatch repair proficient colorectal adenocarcinoma uncovers novel prognostic subgroups with differing patterns of genetic evolution.

Braxton David R, Zhang Ray, Morrissette Jennifer D, Loaiza-Bonilla Arturo, Furth Emma E, International journal of cancer 139(7): 1546-56, 2016, PMID:27194209

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Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.

Ruella Marco, Barrett David M, Kenderian Saad S, Shestova Olga, Hofmann Ted J, Perazzelli Jessica, Klichinsky Michael, Aikawa Vania, Nazimuddin Farzana, Kozlowski Miroslaw, Scholler John, Lacey Simon F, Melenhorst Jan J, Morrissette Jennifer J D, Christian David A, Hunter Christopher A, Kalos Michael, Porter David L, June Carl H, Grupp Stephan A, Gill Saar, The Journal of clinical investigation 126(10): 3814-3826, 2016, PMID:27571406

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors.

Fox Alan J, Hiemenz Matthew C, Lieberman David B, Sukhadia Shrey, Li Barnett, Grubb Joseph, Candrea Patrick, Ganapathy Karthik, Zhao Jianhua, Roth David, Alley Evan, Loren Alison, Morrissette Jennifer J D, Journal of visualized experiments : JoVE, 2016, PMID:27684276

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Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.

Ho Tzu-Chieh, LaMere Mark, Stevens Brett M, Ashton John M, Myers Jason R, O'Dwyer Kristen M, Liesveld Jane L, Mendler Jason H, Guzman Monica, Morrissette Jennifer D, Zhao Jianhua, Wang Eunice S, Wetzler Meir, Jordan Craig T, Becker Michael W, Blood 128(13): 1671-8, 2016, PMID:27421961

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Detection of therapeutically targetable driver and resistance mutations in lung cancer patients by next generation sequencing of cell-free circulating tumor DNA.

Thompson Jeffrey C, Yee Stephanie S, Troxel Andrea B, Savitch Samantha L, Fan Ryan, Balli David, Lieberman David B, Morrissette Jennifer D, Evans Tracey L, Bauml Joshua, Aggarwal Charu, Kosteva John A, Alley Evan, Ciunci Christine, Cohen Roger B, Bagley Stephen, Stonehouse-Lee Susan, Sherry Victoria E, Gilbert Elizabeth, Langer Corey, Vachani Anil, Carpenter Erica L, Clinical cancer research : an official journal of the American Association for Cancer Research 22(23): 5772-5782, 2016, PMID:27601595

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BRAF kinase domain mutations in de novo acute myeloid leukemia with monocytic differentiation.

Xu Youyuan, Wertheim Gerald, Morrissette Jennifer J D, Bagg Adam, Leukemia & lymphoma, 2016, PMID:27545333

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Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.

Luskin Marlise R, Carroll Martin, Lieberman David, Morrissette Jennifer J D, Zhao Jianhua, Crisalli Lisa, Roth David B, Luger Selina M, Porter David L, Reshef Ran, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 22(11): 1961-1967, 2016, PMID:27478011

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A novel approach for next-generation sequencing of circulating tumor cells.

Yee Stephanie S, Lieberman David B, Blanchard Tatiana, Rader JulieAnn, Zhao Jianhua, Troxel Andrea B, DeSloover Daniel, Fox Alan J, Daber Robert D, Kakrecha Bijal, Sukhadia Shrey, Belka George K, DeMichele Angela M, Chodosh Lewis A, Morrissette Jennifer J D, Carpenter Erica L, Molecular genetics & genomic medicine 4(4): 395-406, 2016, PMID:27468416

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