Jennifer J.D. Morrissette, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine
Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817
Email: jennifer.morrissette@uphs.upenn.edu
Specialty Division
Precision and Computational Diagnostics
Education
B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992
Specialty Certification
American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004
Postgraduate Training
Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002
Awards and Honors
Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013
Memberships and Professional Organizations
American Society Human Genetics, 1998 - Present
Philadelphia Genetics Group, 2004 - Present
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Association of Molecular Pathology, 2011 - Present
Web Links
Selected Publications
Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer.
Maxwell Kara N, Soucier-Ernst Danielle, Tahirovic Emin, Troxel Andrea B, Clark Candace, Feldman Michael, Colameco Christopher, Kakrecha Bijal, Langer Melissa, Lieberman David, Morrissette Jennifer J D, Paul Matt R, Pan Tien-Chi, Yee Stephanie, Shih Natalie, Carpenter Erica, Chodosh Lewis A, DeMichele Angela, Breast cancer research and treatment, 2017, PMID:28500398
Most Myeloid Neoplasms With Deletion of Chromosome 16q Are Distinct From Acute Myeloid Leukemia With Inv(16)(p13.1q22): A Bone Marrow Pathology Group Multicenter Study.
Rogers Heesun J, Hsi Eric D, Tang Guilin, Wang Sa A, Bueso-Ramos Carlos E, Lubin Daniel, Morrissette Jennifer J D, Bagg Adam, Cherukuri Durga P, George Tracy I, Peterson LoAnn, Liu Yen-Chun, Mathew Susan, Orazi Attilio, Hasserjian Robert P, American journal of clinical pathology 147(4): 411-419, 2017, PMID:28375434
Molecular and cytogenomic profiling of hepatic adenocarcinoma expressing inhibinA, a mimicker of neuroendocrine tumors: proposal to reclassify as "cholangioblastic variant of intrahepatic cholangiocarcinoma".
Braxton David R, Saxe Debra, Damjanov Nevena, Stashek Kristen, Shroff Stuti, Morrissette Jennifer D, Tondon Rashmi, Furth Emma E, Human pathology 62(): 232-241, 2017, PMID:28232156
Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia.
Tasian Sarah K, Kenderian Saad S, Shen Feng, Ruella Marco, Shestova Olga, Kozlowski Miroslaw, Li Yong, Schrank-Hacker April, Morrissette Jennifer J D, Carroll Martin, June Carl H, Grupp Stephan A, Gill Saar, Blood 129(17): 2395-2407, 2017, PMID:28246194
Molecular and Cytogenomic Profiling of Hepatic Adenocarcinoma Expressing Inhibin, a Mimicker of Neuroendocrine Tumors: Proposal to Reclassify as "Cholangioblastic Variant of Intrahepatic Cholangiocarcinoma"
Braxton DR, Saxe D, Damjanov N, Stashek K, Shroff S, Morrissette JD, Tondon R, Furth EE., Hum Pathol., 2017, PMID:28232156
Optimized Depletion of Chimeric Antigen Receptor T-Cells in Murine Xenograft Models of Human Acute Myeloid Leukemia.
Tasian SK, Kenderian SS, Shen F, Ruella M, Shestova O, Kozlowski M, Li Y, Schrank-Hacker A, Morrissette JJ, Carroll M, June CH, Grupp SA, Gill S., Blood, 2017, PMID:28246194
Marginal zone lymphoma-derived interfollicular diffuse large B-cell lymphoma harboring 20q12 chromosomal deletion and missense mutation of BIRC3 gene: a case report.
Hatem Joseph, Schrank-Hacker April M, Watt Christopher D, Morrissette Jennifer J D, Rubin Adam I, Kim Ellen J, Nasta Sunita D, Wasik Mariusz A, Bogusz Agata M, Diagnostic pathology 11(1): 137, 2016, PMID:27993143
Utilization of next generation sequencing identifies potentially actionable mutations in chronic lymphocytic leukaemia.
Wang J, Morrissette J, Lieberman DB, Timlin C, Schuster SJ, Mato AR., Br J Haematol., 2016, PMID:27714764
Clinicopathogenomic analysis of mismatch repair proficient colorectal adenocarcinoma uncovers novel prognostic subgroups with differing patterns of genetic evolution.
Braxton David R, Zhang Ray, Morrissette Jennifer D, Loaiza-Bonilla Arturo, Furth Emma E, International journal of cancer 139(7): 1546-56, 2016, PMID:27194209
Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.
Ruella Marco, Barrett David M, Kenderian Saad S, Shestova Olga, Hofmann Ted J, Perazzelli Jessica, Klichinsky Michael, Aikawa Vania, Nazimuddin Farzana, Kozlowski Miroslaw, Scholler John, Lacey Simon F, Melenhorst Jan J, Morrissette Jennifer J D, Christian David A, Hunter Christopher A, Kalos Michael, Porter David L, June Carl H, Grupp Stephan A, Gill Saar, The Journal of clinical investigation 126(10): 3814-3826, 2016, PMID:27571406
