PEOPLE

Jennifer J.D. Morrissette, PhD

Associate Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine

Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817

Email: jennifer.morrissette@uphs.upenn.edu

Specialty Division

Precision and Computational Diagnostics

Education

B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992

Specialty Certification

American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004

Postgraduate Training

Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002

Awards and Honors

Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013

Memberships and Professional Organizations

American Society Human Genetics, 1998 - Present
Philadelphia Genetics Group, 2004 - 2018
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Association of Molecular Pathology, 2011 - Present
American Society for Clinical Pathology (ASCP) Immuno-Oncology Working Group, 2018 - Present
International Federation of Clinical Chemistry and Laboratory Medicine, 2019 - Present

Web Links


Selected Publications

Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia

Velu, PD, Perl, AE, Luger, SM, Bagg, A, Morrissette, JJD, British Journal of Haematology 186(6): 801, 2019

Understanding the Tumor Micro-Environment

Jennifer Morrissette, Jonathan Belman, Andrew Rech, ASCP News Archive, 2019

Identification and Confirmation of Potentially Actionable Germline Mutations in Tumor-Only Genomic Sequencing

Dana Farengo Clark, Kara N. Maxwell, Jacquelyn Powers, David B. Lieberman, Jessica Ebrahimzadeh, Jessica M. Long, Danielle McKenna, Payal Shah, Angela Bradbury, Jennifer J.D. Morrissette, Katherine L. Nathanson, and Susan M. Domchek, JCO Precision Oncology 2019(3): 1-11, 2019

Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia

McMahon Christine M, Ferng Timothy, Canaani Jonathan, Wang Eunice S, Morrissette Jennifer J D, Eastburn Dennis J, Pellegrino Maurizio, Durruthy-Durruthy Robert, Watt Christopher D, Asthana Saurabh, Lasater Elisabeth A, DeFilippis RosaAnna, Peretz Cheryl A C, McGary Lisa H F, Deihimi Safoora, Logan Aaron C, Luger Selina M, Shah Neil P, Carroll Martin, Smith Catherine C, Perl Alexander E, Cancer Discovery 9(8): 1050-1063, 2019, PMID:31088841

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Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer

Kraya Adam A, Maxwell Kara N, Wubbenhorst Bradley, Wenz Brandon M, Pluta John, Rech Andrew J, Dorfman Liza M, Lunceford Nicole, Barrett Amanda, Mitra Nandita, Morrissette Jennifer J D, Feldman Michael, Nayak Anupma, Domchek Susan M, Vonderheide Robert H, Nathanson Katherine L, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 25(14): 4363-4374, 2019, PMID:30914433

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Clinically Determined Fusions in Gliomas: An Institutional Experience with a Fusion Transcript Panel

Nasrallah, M, Bagley, S, Desai, A, Sussman, R, Morrissette, J, Journal of Neuropathology and Experimental Neurology 78(6): 529, 2019

Validation of a Next-Generation Sequencing Assay Targeting RNA for the Multiplexed Detection of Fusion Transcripts and Oncogenic Isoforms

Sussman Robyn T, Oran Amanda R, Paolillo Carmela, Lieberman David, Morrissette Jennifer J D, Rosenbaum Jason N, Archives of Pathology & Laboratory Medicine, 2019, PMID:31211614

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Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma

Nasrallah, MP, Binder, ZA, Oldridge, DA, Zhao, J, Lieberman, DB, Roth, JJ, Watt, CD, Sukhadia, S, Klinman, E, Daber, RD, Desai, A, Brem, S, O'Rourke, DM, Morrissette, JJD, Academic Pathology 6(): , 2019

Gilteritinib induces differentiation in relapsed and refractory -mutated acute myeloid leukemia

McMahon Christine M, Canaani Jonathan, Rea Bryan, Sargent Rachel L, Qualtieri Julianne N, Watt Christopher D, Morrissette Jennifer J D, Carroll Martin, Perl Alexander E, Blood Advances 3(10): 1581-1585, 2019, PMID:31122910

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FBXW7 mutations in acute myeloid leukemia

Sadigh, S, Morrissette, JJD, Bagg, A, Leukemia & Lymphoma 60(6): 1601-1602, 2019