Vinodh Pillai, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
University of Pennsylvania Perelman School of Medicine

Contact InformationThe Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Philadelphia, PA, 19104
Fax: 215-590-1736

Research Expertise

CAR T cell therapy
Pediatric hematopoietic malignancies
Acute lymphoblastic leukemia
Castleman disease
Juvenile myelomonocytic leukemia
Kikuchi-Fujimoto lymphadenitis

Clinical Expertise

Pediatric Hematopathology including leukemias and lymphomas
Pathology of CAR T cell therapy in B-ALL


M.B.B.S. (Medicine and Surgery), Madras Medical College, 2002
Ph.D. (Biomedical sciences Immunology), University of Texas Southwestern Medical Center , 2007

Specialty Certification

American Board of Pathology (Anatomic and Clinical Pathology), 2013
American Board of Pathology Hematology, 2014

Postgraduate Training

Post-doctoral fellow of the National Multiple Sclerosis Society, Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, 2007-2009
Anatomic and Clinical Pathology Residency, Brigham and Women’s Hospital, Boston, MA, 2009-2013
Hematopathology Fellowship , Brigham and Women’s Hospital, Dana Farber Cancer Institute and Boston
Children's Hospital Boston, MA, 2013-2014

Awards and Honors

Top 5 Poster Award in GSO Poster Competition, 2005
Graduate Student Organization (GSO) Travel Award, 2007
Eliot Goldings Award for the Best Graduating Student in Immunology, 2007
BWH Biomedical Research Institute Microgrant Award, 2012
Paul E. Strandjord Young Investigator Award from the Academy of Clinical Laboratory Physicians and Scientists, 2013
Children's Oncology Group young investigator mentorship program, 2017-current
SIOP (International Society of Paediatric Oncology) Young Investigator Award, 2018
HTG EdgeSeq 2020 Autoimmune Panel Research Grant award, 2020

Memberships and Professional Organizations

American Association of Immunologists, 2007 - 2009
Clinical Immunology Society, 2007 - 2009
United States and Canadian Academy of Pathology, 2011 - 2014
American Society for Clinical Pathology, 2012 - Present
Academy of Clinical Laboratory Physicians and Scientists, 2013 - 2015
International Clinical Cytometry Society, 2015 - present
Children's Oncology Group, 2015 - Present
Society for Hematopathology, 2015 - Present
Foundation Medicine, 2017 - 2020
American Society for Clinical Oncology, 2018 - Present
College of American Pathologists, 2018 - Present
College of American Pathologists, 2019 - 2020

Web Links

Selected Publications

Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse.

Sophia Faude, Jane Wei, Kavitha Muralidharan, Xiaoming Xu, Gerald Wertheim, Michele Paessler, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold, and Vinodh Pillai, Blood Advances 5(8): 2128-2136, 2021, PMID:33881465

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Blinatumomab Induces Bone Marrow Lymphoid Infiltrates That Correlate with Response in B-ALL

Lytle A, Pillai V, Wertheim GW, Paessler M, Croy C and Rheingold S, United States and Canadian Academy of Pathology 2021 Baltimore, Maryland, 2021

Morphological and Immunophenotypic Characterization of CAR T Cells

Wei J, Faude S, Xu X, Wertheim G, Paessler M, Bhoj V, Pillai V, United States and Canadian Academy of Pathology 2021 Baltimore, Maryland, 2021

Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease

Nya D Nelson 1 2, Wenzhao Meng 1, Aaron M Rosenfeld 1, Susan Bullman 3 4 5, Chandra Sekhar Pedamallu 3 4 5, Jason L Nomburg 3 4 5, Gerald B Wertheim 2, Michele E Paessler 1 2, Geraldine Pinkus 5, Jason L Hornick 5, Matthew Meyerson 3 4 5, Eline T Luning Prak 1, Vinodh Pillai, Pediatr Dev Pathol., 2021

NTRK Fusions Identified in Pediatric Tumors: The Frequency, Fusion Partners, and Clinical Outcome

Zhao X, Kotch C, Fox E, Surrey L, Wertheim GB, Baloch ZW, Lin F, P:illai V, Luo M, Kreiger PA, Pogoriler JE, Linn RL, Russo PA, Santi M, Resnick AC, Storm PB, Hunger SP, Bauer AJ and Li MM, JCO Precision Oncology, 2021

DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells

Jung-Yeon Lim, Sascha Duttke, Turner Baker, Jihye Lee, Kristyne Gambino, Nicholas Venturini, Jessica Sook Yuin Ho, Simin Zheng, Yesai Fstkchyan, Vinodh Pillai, David Fajgenbaum, Ivan Marazzi, Christopher Benner, and Minji Byun, Journal of Experimental Medicine, 2021

Participation in the College of American Pathologists Laboratory Accreditation Program Decreases Variability in B-Lymphoblastic Leukemia and Plasma Cell Myeloma Flow Cytometric Minimal Residual Disease Testing: A Follow-up Survey

Hupp MM, Bashleben C, Cardinali JL, Dorfman DM, Karlon W, Keeney M, Leith C, Long T, Murphy CE, Pillai V, Rosado FN, Seegmiller AC, Linden MA., Archives of Pathology and Laboratory Medicine, 2020, PMID:32886757

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Evolution of Histomorphologic, Cytogenetic, and Genetic Abnormalities in an Untreated Patient With MIRAGE Syndrome

Rentas S, Pillai V, Wertheim GB, Akgumus GT,Nichols KE, Deardorff MA, Conlin LK, Li MM, Olson TS, Luo M, Cancer Genetics 245(): 42-48, 2020, PMID:32619790

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Transient atypical monocytosis after α/β T-cell-depleted haploidentical hematopoietic stem cell transplantation

Liou A, Van Arnam J, Pillai V, Seif AE, Tasian SK, Phillips CA, Pediatric Blood and Cancer 67(4): , 2020, PMID:31867817

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CD19-Negative B-ALL Relapses after CAR T Cell Therapy are Associated with a Hypermutator Phenotype

Yang G, Faude S, Paessler ME, Wertheim GBW, Pillai V, United States and Canadian Academy of Pathology 2020 Los Angeles, California, 2020