PEOPLE

Kojo Elenitoba-Johnson, MD

Peter C. Nowell, M.D., Professor
University of Pennsylvania Perelman School of Medicine
Director, Center for Personalized Diagnostics
Director, Division of Precision and Computational Diagnostics

Contact InformationDepartment of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
609 Stellar-Chance
422 Curie Blvd.
Philadelphia, PA, 19104-6100
Office: 215-898-8198
Fax: 215-898-9969

Specialty Division

Precision and Computational Diagnostics

Itmat Expertise

Molecular pathogenesis, biomarkers and therapeutic targets of malignant lymphoid neoplasia

Education

MD (Medicine), College of Medicine, University of Lagos and Lagos University Teaching Hospital, 1988

Specialty Certification

Educational Commission for Foreign Medical Graduates Certification (ECFMG), 1988
Diplomate of American Board of Pathology (Combined Anatomic Pathology and
Clinical Pathology), 1996
Diplomate of American Board of Pathology (Hematology), 1998
New York State Certification of Qualification for Molecular Oncology and Hematopathology, 1998
Diplomate of American Board of Pathology (Molecular Genetic Pathology), 2001
New York State Department of Health, Certificate of Qualification for Laboratory Director for Hematology, Histopathology General and Oncology Molecular and Cellular Tumor Markers, 2008

Postgraduate Training

Residency, Anatomic and Clinical Pathology, Brown University School of Medicine, Providence, Rhode Island, 1991-1995
Chief Resident, Department of Pathology, Brown University School of Medicine, Providence, RI, 1992-1994
Fellowship, Hematopathology, Lab of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 1995-1997
Leadership Development for Physicians in Academic Health Centers, Harvard School of Public Health, Cambridge, MA, 2012-2012
Linkage Leadership Academy, University of Michigan, MA, 2013-2013

Awards and Honors

“Concepts in Molecular Pathology”, American Society of Investigative Pathology Scholarship, 1993
Outstanding Graduating Resident Award, Brown University Residency Training Program, 1995
Pathologist in Training Award, Society for Hematopathology, 1998
Outstanding Teaching Award in Anatomic Pathology, University of Utah Department of
Pathology, 1999
Best Doctors in America honoree, 2003-2018
Outstanding Teaching Award in Anatomic Pathology, University of Utah Department of
Pathology, 2003
Ramzi Cotran Young Investigator Award, United States and Canadian Academy of Pathology, 2006
Finalist, Burroughs Welcome Fund Clinical Scientist Award in Translational Research, 2007
League of Research Excellence, University of Michigan, 2011
Henry C. Bryant Endowed Professorship, Department of Pathology, University of Michigan, 2011
Elected Member, American Society for Clinical Investigation Society, 2011
American Society for Investigative Pathology Outstanding Investigator Award (formerly the
ASIP Amgen, Pfizer, Warner-Lambert-Parke-Davis Award), 2012
Elected Member, American Association of University Pathologists (PLUTO Society), 2013
Peter C. Nowell, M.D., Endowed Professorship, Perelman School of Medicine, University of Pennsylvania Health System, 2015
Member nomination-December 2016 - John Morgan Society of the University of Pennsylvania, 2016
Member - Interurban Clinical Club, 2016
President-Elect/Association for Molecular Pathology, 2016-2017

Memberships and Professional Organizations

American Society for Clinical Pathology, 1991 - Present
New England Pathology Residents’ Society, 1992 - 1993
United States and Canadian Academy of Pathology, 1995 - Present
Association for Molecular Pathology, 1997 - Present
American Society of Hematology, 1997 - Present
Society for Hematopathology/European Association for Haematopathology, 1998 - Present
American Society for Investigative Pathology, 2001 - Present
National Institutes of Health, National Cancer Institute, 2003 - Present
American Society for Biochemistry and Molecular Biology, 2005 - Present
Michigan Society of Pathologists, 2006 - Present
Lymphoma Research Foundation, 2007 - Present
Food and Drug Administration (FDA), 2008 - Present
Netherlands Cancer Institute, 2009 - 2009
National Institutes of Health Center for Scientific Review, 2010 - 2014
American Society of Clinical Investigation, 2011 - Present
National Institutes of Health, Bethesda, MD, 2013 - 2018
American Association for Cancer Research, 2014 - Present
International Lymphoma Study Group, 2015 - Present
Interurban Clinical Club, 2016 - Present
National Cancer Policy Forum of The National Academies of Sciences, Engineering and Medicine, 2017 - 2020
United States and Canadian Academy of Pathology, 2018 - 2022

Web Links


Selected Publications

Novel Insights into the pathogenesis of T-cell lymphomas

Van Arnam JS, Lim MS, Elenitoba-Johnson KSJ, Blood 11(): , 2018, PMID:29666117

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Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.

2. Schrader A, Crispatzu G, Oberbeck S, Mayer P, Pützer S, von Jan J, Vasyutina E, Wamer K, Weit N, Pflug N, Braun T, Andersson El, Yadav B, Riabinska A, Maurer B, Ventura Ferreira MS, Beier F, Altmü J, Lanasa M, Herling CD, Haferlach T, Stilgenbauer S, Hopfinger G, Peifer M, Brümmendorf TH, Nürnberg P, Elenitoba-Johnson KSJ, Zha S, Hallek M, Moriggl R, Reinhardt HC Stern MH, Mustjoki S, Newrzela S, Frommolt P, Herling M., Nat Commun. 9(): 697, 2018, PMID:29449575

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Clinical implications of oncogenic mutations in pulmonary Langerthans cell histiocytosis.

Brown NA, Elenitoba-Johnson KSJ, Curr Opin Pulm Med, 2018, PMID:29470255

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A metabolic function of FGFR3-TACC3 gene fusions in cancer.

Frattini V, Pagnotta SM, Tala, Fan JJ, Russo MV, Lee SB, Garofano L, Zhang J, Shi P, Lewis G, Sanson H, Frederick, V, castano AM, Cerulo L, Rolland DCM, Mall R, Mokhtari K, Elenitoba-Johnson KSJ, Sanson M, Huang X, Ceccarelli M, Lasorella A, Iavarone A., Nature 553(7687): 222-227, 2018, PMID:29323298

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A comparative global phosphoproteomic analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment.

Awasthi A, Rolland DCM, Ayello J, van de Ven C, Basrur V, Conlon K, Fermin D, Barth MJ, Klein C, Elenitoba-Johnson KSJ, Lim MS, Cairo MS., Oncotarget. 8(): 113895-113909, 2017, PMID:29371955

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Human papillomavirus (HPV) and somatic EGFR mutations are essential, mutually exclusive oncogenic mechanisms for inverted sinonasal papillomas and associated sinonasal squamous cell carcinomas.

Udager AM, McHugh JB, Goudsmit SM, Weigelin HC, Lim MS, Elenitoba-Johnson KSJ, Betz BL, Carey TE, Brown NA, Ann Oncol, 2017, PMID:29145573

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New Insights into Lymphoma Pathogenesis

Elenitoba-Johnson KSJ, Lim MS, Annu Rev Pathol, 2017, PMID:29140757

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Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas.

Rolland DCM, Basrur V, Jeon YK, McNeil-Schwalm C, Fermin D, Conlon KP, Zhou Y, Ng SY, Tsou C-C, Brown NA, Thomas DG, Bailey NG, Omenn GS, Nesvizhskii AI, Weinstock DM, Faryabi RB, Lim MS, Elenitoba-Johnson KSJ, Proceedings of the National Academy of Sciences of the United States of America 114(25): 6581-6586, 2017, PMID:28607076

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International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic Multicentric Castleman disease

Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Shanmuganathan C, Lechowicz MJ, Wong RSM, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel C, Casper C, Dispenzieri A, Fossa A, Kelleher D, Kurzock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KSJ, Lim MS., Blood, 2017, PMID:28087540

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Senescent stromal cell-induced divergence and therapeutic resistance in T-cell acute lymphoblastic leukemia/lymphoma.

Habiel DM, Krepostman N, Lilly M, Cavassani K, Coelho AL, Shibata T, Elenitoba-Johnson KSJ, Hogaboam CM., Oncotarget, 2016, PMID:27835864

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