Jason N. Rosenbaum, MD

Assistant Professor of Clinical Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine

Contact Information3020 Market Street, Suite 220
Philadelphia, PA 19128
Office: 267-586-2525
Fax: 215-898-9817


Specialty Division

Precision and Computational Diagnostics

Itmat Expertise

Diagnostic and prognostic test design

Clinical Expertise

Molecular Diagnostics
Massively Parallel (Next-Generation) Sequencing
Molecular Biomarkers
Genomic Alterations in Lung Cancer
Neuroendocrine Neoplasms
Clinical Test Development and Validation


BA (Molecular and Cell Biology/Integrative Biology), University of California at Berkley, 1998
MD (Medicine), Northwestern University Feinberg School of Medicine, 2011

Specialty Certification

Certified by the American Board of Pathology in Anatomic and Clinical Pathology, 2015
Certified by the American Board of Pathology in Molecular Genetic Pathology, 2016

Postgraduate Training

Residency Training, Anatomic and Clinical Pathology, University of Wisconsin Hospital and Clinics, 2011-2015
Fellow, Molecular Genetic Pathology, Washington University, Barnes Jewish Hospital, 2015-2016

Awards and Honors

Chancellor's Scholar, University of California, Berkeley, 1994-1998
BA, High Honors, University of California, Berkeley, 1998
Morton Heller Award for Exemplary Research, 2010
Michael N. Hart Research Day Resident Presentation Award, University of Wisconsin, 2012
University of Wisconsin Research and Development Grant, 2012-2015
Best Poster Finalist, Education Category, American Society for Clinical
Pathology Annual Meeting, Chicago, IL, 2013
Quality Improvement Award, University of Wisconsin Hospital, 2013
ICPI Travel Grant, USCAP Annual Meeting, San Diego, CA, 2014
Michael N. Hart Research Day Resident Presentation Award, University of Wisconsin, 2014
Pilot Award, UWCCC Neuroendocrine Cancer Research Task Force and the Aly Wolff Memorial Fund for Neuroendocrine Carcinoma Research, 2015-2017
Trainee Research Day, Best Presentation Award, Washington University, 2016
Peter C. Nowell, PhD Department of Pathology and Laboratory Medicine Award for Teaching, 2018
Kevin E. Salhany, MD Award for Excellence in Clinical Teaching, 2018

Memberships and Professional Organizations

American Medical Association, 2001 - Present
American Association for the Advancement of Science, 2008 - 2010
Association for Molecular Pathology, 2011 - Present
United States and Canadian Academy of Pathology, 2011 - Present
American Society for Clinical Pathology, 2011 - Present
College of American Pathologists, 2011 - Present
Wisconsin Society of Pathology, 2011 - 2015
Endocrine Society, 2013 - Present
American Society of Human Genetics, 2014 - Present
Digital Pathology Association, 2014 - Present
American Society of Clinical Oncology, 2015 - Present
Wagih Bari Society of St. Louis Pathologists, 2015 - 2016
Pennsylvania Association of Pathologists, 2017 - Present
Pennsylvania State Medical Society, 2017 - Present

Web Links

Selected Publications

Reporting Indeterminate Variants from Massively Parallel Sequencing Assays.

J.J. Roth, D. Lieberman, C.R. Orr, S. Deihimi, C.R. Herzog, K.S. Elenitoba-Johnson, J.J. Morrissette, J.N. Rosenbaum, Journal of Molecular Diagnostics 21(6)(6): 1180, 2019

A Novel Approach to Next-Generation Sequencing-Based Assessment of T-cell Clonality

D.A. Oldridge, C. Gentile, J.N. Rosenbaum, V.M. Van Deerlin, Journal of Molecular Diagnostics 21(6): 1245, 2019

Calculation of Tumor Mutational Burden (TMB) Using a Small, Targeted Next-Generation Sequencing (NGS) Panel for Solid Tumor Samples Absent Matched Normal Samples.

C. Rushton P.D. Velu, D.A. Oldridge, A. Bidgeli, R. Sussman, R.B. Faryabi, J.N. Rosenbaum, Journal of Molecular Diagnostics 21(6): 1178, 2019

Cyclin D1 expression and novel mutational findings in Rosai-Dorfman disease.

Baraban E., Sadigh S., Rosenbaum J., Van Arnam J., Bogusz A.M., Mehr C., Bagg A., British Journal of Haematology, 2019, PMID:31172509

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Impact of KRAS and TP53 co-mutations on outcomes after first-line systemic therapy among patients with STK11 mutated advanced NSCLC

Melina Marmarelis, Erin Bange, Wei-Ting Hwang, Yu-Xiao Yang, Jeffrey C. Thompson, Jason N. Rosenbaum, Joshua M. Bauml, Christine Ciunci, Evan W. Alley, Roger B. Cohem, Corey J. Langer, Erica Carpenter, Charu Aggarwal, JCO Precision Oncology, 2019

Histologic, Immunohistochemical, and Molecular Features of Pituicytomas and Atypical Pituicytomas

Angela N Viaene, Edward B Lee, Jason N. Rosenbaum, Ilya M Nasrallah, MacLean P Nasrallah, Acta Neuropathologica Communications 1(7): , 2019, PMID:31046843

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Thyroid-Like Follicular Carcinoma of the Kidney With Extensive Sarcomatoid Differentiation: A Case Report and Review of the Literature

Taylor M. Jenkins, Jason N. Rosenbaum, Paul J. Zhang, Lauren E. Schwartz, A Nayak, S.K. Tickoo, Priti Lal., International Journal of Surgical Pathology, 2019, PMID:31032708

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Development and Validation of Molecular Assays for Limited Tissue Samples

Robyn Sussman, Jason N. Rosenbaum, Acta Cytologica, 2019, PMID:30995656

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Expression of Insulinoma-Associated Protein 1 (INSM1) and Orthopedia Homeobox (OTP) in Tumors with Neuroendocrine Differentiation at Rare Sites

M. Roy, D.G. Buehler, R. Zhang, M.L. Schwalbe, R.M. Baus, M.S. Salamat, R.V. Lloyd, J.N. Rosenbaum, Endocrine Pathology, 2018, PMID:30523500

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Validation of a Next-Generation Sequencing Oncology Panel Optimized for Low Input DNA

R. Sussman, S.Shaffer, E. Azzato, D. DeSloover, M. Farooqi, A. Meyer, D. Lieberman, A. Bigdeli, C. Paolillo, K. Ganapathy, S. Sukhadia, J.N. Rosenbaum, R. Daber, J. Morrissette, Cancer Genetics, 2018, PMID:30553474

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