Molecular Genetic Pathology


Molecular Genetic Pathology (MGP) is the subspecialty of Pathology and Medical Genetics in which the principles, theory, and technologies of molecular biology and molecular genetics are applied to help to make clinical diagnoses, determine disease prognosis, monitor infections and therapies, and provide risk assessments for genetic disorders. While molecular pathology is fast becoming an essential diagnostic and prognostic instrument in the routine practice of medicine, the subspecialty has already been an integral part of the Penn Department of Pathology and Laboratory Medicine since 1985, when the Molecular Pathology Laboratory was founded as one of the first of its kind at a university hospital in the country. Likewise, Penn was among the first Molecular Pathology training programs in the country in the early 1990s and was one of the first two programs to obtain ACGME accreditation in 2002 after MGP became a recognized subspecialty.


The goal of the Penn MGP program is to train fellows in the practice of molecular pathology and genomics, the application and interpretation of molecular laboratory techniques, and diagnostic laboratory administration. Over the course of the one-year ACGME accredited fellowship the fellow gains experience in the application of molecular pathology through service work, didactic lectures, resident teaching, involvement in laboratory administration, and hands-on test development and/or research projects through rotations at the Hospital of the University of Pennsylvania (HUP) and the Children’s Hospital of Philadelphia (CHOP). Fellows are exposed to clinical genetics through rotations in pediatric and adult clinical genetics and biochemical genetics. At the completion of the fellowship, the trainee will be eligible to take the Molecular Genetic Pathology Board examination.


Up to three MGP fellowship positions are available each year. Candidates must be Board-eligible in either AP and/or CP or Medical Genetics and have passed the USMLE Part 3 exam prior to the start of the program. They must also be licensed or eligible for licensure in Pennsylvania. Prior experience in genetics and/or molecular biology is recommended.

Each academic year begins on the first of July. Applications will be accepted beginning July 1, with an end date of December 31st, 18 months prior to the start of the program. Offers of a position are given on a rolling basis after the start of interviews; therefore, we encourage applicants to submit their applications early, as there is no guarantee that a position will be available. Candidates considered for the program will be asked to interview.

Key Program Faculty

Division of PCD
Kojo Elenitoba-Johnson, MD
Vivianna Van Deerlin, MD, PhD
Christopher Watt, MD, PhD
Warren Pear, MD, PhD
Jennifer Morrissette, PhD
Malay Haldar, MD, PhD
Jason Rosenbaum, MD
Jacquelyn Roth, PhD
Salvatore Priore, MD, PhD

Laurel Glaser, MD

Lea Surrey, MD
Minjie Luo, PhD