National Blood Foundation Early-Career Grant for Dr. Vijay Bhoj

January 07, 2019

The National Blood Foundation (NBF), a program of AABB, has funded a research project by Vijay G. Bhoj, MD, PhD, in the field of transfusion medicine and cellular therapies. His application titled "Dissecting the Humoral Response to FVIII for Therapeutic Applications" was selected by scientific experts of the NBF Grants Review Committee, who thoroughly reviewed the 33 applications received. The NBF will fund this project for $75,000 over two years. The committee recommended Dr. Bhoj's application be funded along with six others. These seven project investigators are the latest researchers to receive funding from the NBF, which has promoted early-career research in the fields of transfusion medicine and cellular therapies for more than three decades.

Dr. Bhoj's Project Summary:
Patients with Hemophilia A (HA), caused by a genetic deficiency of coagulation factor VIII (FVIII), suffer from life-threatening bleeding. Following FVIII replacement, the optimal treatment, 30% of patients develop anti-FVIII antibodies, which nullifies the therapy. This proposal is centered on (1) understanding fundamental features of the antibody response to FVIII in patients and (2) evaluating novel therapies aimed at eradicating such antibodies.

See AABB press release.