Latest Results of Investigational Cellular Therapy CTL019 at ASH

December 08, 2014

Highlights of the new trial results include a response rate of more than 90 percent among pediatric ALL patients, and results from the first lymphoma trials testing the approach, including a 100 percent response rate among follicular lymphoma patients and 45 percent response rate among those with diffuse large B cell lymphoma.

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Dr. Malek Kamoun Elected President of ASHI

November 14, 2014

Dr. Kamoun assumes the 2014-15 Presidency of the American Society for Histocompatibility and Immunogenetics (ASHI).

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Landmark Mitochondria Study Offers New Insights into Causes of Metabolic, Degenerative Diseases

October 30, 2014

Wallace Lab findings challenge the traditional “single mutation–single disease” concept and provide an alternative perspective into understanding the underlying cause of metabolic and neurodegenerative disorders.

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DOD Grant for Lupus Research

October 29, 2014

Michael P. Cancro, PhD, is one of three recipients of grants totaling $3.4 million that have been awarded by the U.S. Department of Defense (DOD) for lupus research. 

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$12 Million DARPA Award for Synthetic DNA Vaccines

October 20, 2014

The Defense Advanced Research Projects Agency (DARPA) has awarded $12.2 million for a project to develop DNA-based monoclonal antibodies (mAbs) for infectious disease treatment.

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Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

October 16, 2014

Ninety percent of children and adults with acute lymphoblastic leukemia (ALL) who had relapsed multiple times or failed to respond to standard therapies went into remission after receiving an investigational personalized cellular therapy, CTL019, developed at the Perelman School of Medicine at the University of Pennsylvania. The unprecedented results are published this week in The New England Journal of Medicine.

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2014 ASCP Annual Meeting Awards

October 13, 2014

Honors for Dr. Virginia LiVolsi, Dr. Zubair Baloch, and fourth-year resident Dr. Sam Wei.

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Nicholas K. Gonatas, MD (1930-2014)

October 07, 2014

The Department mourns the death of Dr. Nicholas Gonatas, Professor of Pathology and Laboratory Medicine, luminary neuropathologist, world-class researcher, founder of the Division of Neuropathology at Penn, and outstanding teacher and mentor to scores of pathology fellows, residents, graduate students, and postdoctoral fellows.

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Chen Lab Publishes in Cancer Cell

September 22, 2014

In a study that sheds light on how phospholipid signals are controlled during tumorigenesis, the Chen Lab reports that TIPE3, a newly described oncogenic protein, is the transfer protein of phosphoinositide second messengers that promote cancer.

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Penn Medicine and Wistar Receive $12 Million NCI Melanoma Grant

September 17, 2014

Melanoma physicians and researchers from Penn Medicine and The Wistar Institute have been awarded a prestigious $12.1 million NCI SPORE grant. 

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