Close to 80 Department faculty members are engaged in basic science, translational, and clinical research across the Penn campus, including research programs at the Perelman School of Medicine, the Abramson Cancer Center of the University of Pennsylvania, and The Children's Hospital of Philadelphia, and encompassing the areas of Bioinformatics, Cancer Biology, Cardiovascular Pathobiology, Cell Biology and Signal Transduction, Developmental Mechanisms, Developmental, Stem Cell, & Regenerative Biology, Genetics and Gene Regulation, Neurodegenerative Diseases, Orphan Diseases, Proteomics, Recombination, Class Switching, DNA Repair.
With a longstanding research focus on fundamental biophysical aspects of diseases, the Department is one of the few places where the basic science divisions and clinical practices are still linked, thus bridging the medical school and health services. Resulting advantages to both include providing resources, intellectual and financial; fostering translational research; ensuring that basic science observations are applied towards patient treatment and diagnosis; and establishing accessibility and dialogue between clinicians and basic scientists.
These efforts are supported by:
- A wide range of individual research laboratories
- Department-based institutes and centers designed to strengthen interdisciplinary research
- Inter-disciplinary programs for translational research efforts and clinical trials, leveraging the expertise of departmental faculty members with clinical service missions, and promote development of new clinical diagnostic tests
- Core laboratories founded by the Department that offer access to cutting-edge molecular, imaging and bioinformatics technologies