Hot Topics

publication

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

A new Penn Medicine preclinical study in Cell, "Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade," suggests that an existing drug known as a JAK in

Read more
publication

Reengineering Chimeric Antigen Receptor T Cells for Targeted Therapy of Autoimmune Disease

In a Science study with potentially major implications for the future treatment of autoimmunity and related conditions, co-senior author

Read more
News

Science Paper Describes Reengineered Chimeric Antigen Receptor T Cells for Targeted Therapy of Autoimmune Disease

Application could open up anti-cancer CAR approach to treatment for a much wider range of diseases, including autoimmunity and transplant rejection.

Read more
News

Double Targeted CAR-T Scores in Preclinical Cancer Study for Solid Tumors

Paper in Immunity describes CAR T-Cells' effectiveness in mouse models of pancreatic cancer.

Read more
News

Clinical Trial for Personalized Immunotherapy in Glioblastoma

Results from nine patients with brain tumor reported at AACR.

Read more
News

Clinical Research Awards for Studies on T Cell Therapies to Treat Multiple Myeloma

Dr. Carl June's myeloma research publications in NEJM and Nature Medicine among the year’s ten most outstanding research papers.

Read more