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A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas

Cell Reports study from Pear Lab links mutations in Notch gene to role in B-cell cancers.

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ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model

Article received Research Innovation in Scientific Excellence (RISE) Award for best original research article published each year in Transfusion journal.

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Association Between Mitochondrial DNA Haplogroup Variation and Autism Spectrum Disorders

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study in JAMA Psychiatry led by

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An Atlas of B-cell Clonal Distribution in the Human Body

A new “anatomic atlas” of how B cells – the immune system’s producer of antibodies – link up to form networks has been charted by researchers led by senior author Dr. Nina Luning Prak.

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Pilot Study Tests CAR T-Cell Immunotherapy in Glioblastomas

Science Translational Medicine reports results of phase 1 safety study of autologous CAR T cells targeted to EGFR variant III in glioblastoma patients.

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Nature Genetics Study on Rare Gene Variants Implicates Innate Immunity in Alzheimer's Disease

Three new coding variants found in genome-wide association study point to the brain’s immune cells in the onset of the disorder.

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