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Association Between Mitochondrial DNA Haplogroup Variation and Autism Spectrum Disorders

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study in JAMA Psychiatry led by

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An Atlas of B-cell Clonal Distribution in the Human Body

A new “anatomic atlas” of how B cells – the immune system’s producer of antibodies – link up to form networks has been charted by researchers led by senior author Dr. Nina Luning Prak.

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Pilot Study Tests CAR T-Cell Immunotherapy in Glioblastomas

Science Translational Medicine reports results of phase 1 safety study of autologous CAR T cells targeted to EGFR variant III in glioblastoma patients.

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Nature Genetics Study on Rare Gene Variants Implicates Innate Immunity in Alzheimer's Disease

Three new coding variants found in genome-wide association study point to the brain’s immune cells in the onset of the disorder.

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Medical Alumni Weekend 2017: Penn Medicine at the Forefront

A Penn panel of nationally renowned faculty discusses the most promising areas of discovery at Penn Medicine today.

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Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Bacteria in the gut microbiome drive the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, accord

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