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Evidence That Two Common Gene Variants in Minority Populations Cause Kidney Disease

New study in Nature Medicine by Penn researchers provides direct evidence that two common gene variants in minority populations cause chronic and end-stage kidney disease.

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Non-Transgenic Mouse Model of Sporadic Tauopathies

Video on Penn's newly developed animal model using neurofibrillary tangles from Alzheimer's brains to replicate Alzheimer's pathology and spreading in mice.

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Dr. Douglas Wallace Recipient of the 2017 Benjamin Franklin Medal in Life Science

Prestigious international award recognizes Dr. Wallace as the founder of the field of mitochondrial medicine, opening up novel insights into rare and common diseases, as well as tracing human evolution.

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The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

The lab of Jorge Menao-Mejia, MD, PhD, has published a study in Nature that finds that long non-coding RNAs (ln

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Henao-Mejia Lab Discovers a Novel lncRNA Critical for the Survival of Myeloid Cells

Nature paper identifies new drug target for inflammatory disorders.

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Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Rare Disease

Cell Stem Cell paper identifies link between telomeres and the molecular signaling cascade Wnt pathway that may point to a treatment option for the rare, inherited disease Dyskeratosis congenita (DC).

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