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Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Bacteria in the gut microbiome drive the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, accord

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Dr. Michael Milone Receives National Clinical Research Achievement Award

Prestigious 2017 Clinical Research Forum Award for Science paper on innovative approach using chimeric autoantibody receptor (CAAR) T cells as a targeted therapy of autoimmunity.

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Evidence That Two Common Gene Variants in Minority Populations Cause Kidney Disease

New study in Nature Medicine by Penn researchers provides direct evidence that two common gene variants in minority populations cause chronic and end-stage kidney disease.

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Non-Transgenic Mouse Model of Sporadic Tauopathies

Video on Penn's newly developed animal model using neurofibrillary tangles from Alzheimer's brains to replicate Alzheimer's pathology and spreading in mice.

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Dr. Douglas Wallace Recipient of the 2017 Benjamin Franklin Medal in Life Science

Prestigious international award recognizes Dr. Wallace as the founder of the field of mitochondrial medicine, opening up novel insights into rare and common diseases, as well as tracing human evolution.

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publication

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

The lab of Jorge Menao-Mejia, MD, PhD, has published a study in Nature that finds that long non-coding RNAs (ln

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