Lisa Eidenschink Brodersen, PhD
Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania
Contact Information3401 Civic Center Blvd.
Philadelphia, PA, 19104
Email: brodersenl@chop.edu
Education
BA (Chemistry and Biology), St. Olaf College , 2003
PhD (Chemistry), University of Washington , 2009
Specialty Certification
American Board of Bioanalysis
High Complexity Laboratory Director Diplomat (Hematology), 2017
Postgraduate Training
Post-Doctoral Scientist, Hematologics Inc., 2009-2011
Awards and Honors
Board Certified High Complexity Laboratory Director – American Board of Bioanalysis (ABB), 2017
Best Abstract Nominee – American Society of Hematology (ASH) Annual Meeting, 2020
Memberships and Professional Organizations
European LeukemiaNet Working Group for Flow Cytometry in
Myelodysplastic Syndromes (IMDSFLOW), 2011 - Present
American Society of Hematology, 2017 - Present
Children’s Oncology Group Myeloid Disease Committee, 2017 - 2023
Fred Hutchinson Cancer Center, 2021 - 2023
Web Links
Selected Publications
Molecular risk markers define risk of relapse in myeloid leukemia of Down syndrome beyond measurable residual disease
Berman JN, Verma A, Viola S, Alonzo TA, Wang YC, Brodersen LE, Loken M, Beckman A, Hirsch B, Raimondi S, Chisholm KM, Ma X, Ries R, Meshinchi S, Gamis A, Schore R, Taub JW, Kolb EA, Cooper T, Hitzler J, Blood Advances 10(5): 1576–1586, 2026
Diagnosis and Management of AML in Pediatric Patients: Consensus Recommendations from an International Expert Panel
Zwaan CM, Tasian SK, Aplenc R, Brodersen LE, Buldini B, De Moerloose B, Dworzak MN, Fogelstrand L, Gibson BE, Goemans BF, Hasle H, Hirsch BA, Kaspers GJ, Klusmann JH, Kutny MA, Lehrnbecher T, Locatelli F, Meshinchi S, Petit A, Pigazzi M, Tierens A, Kolb EA, Reinhardt D, Tomizawa D, Cooper TM, Blood, 2025, PMID:41105890
CD74 is Expressed in a Subset of Pediatric Acute Myeloid Leukemia Patients and is a Promising Target for Therapy: a Report From the Children's Oncology Group
Menssen AJ, Hudson CA, Alonzo T, Gerbing R, Pardo L, Leonti A, Cook JA, Hsu FC, Lott LL, Dai F, Fearing C, Ghirardelli K, Hylkema T, Tarlock K, Loeb KR, Kolb EA, Cooper T, Pollard J, Wells DA, Loken MR, Aplenc R, Meshinchi S, Eidenschink Brodersen L, Haematologica 109(10): 3182-3193, 2024, PMID:38299667
Measurable Residual Disease Assessment in Pediatric AML
Pigazzi M, Tregnano C, Hudson CA, and Eidenschink Brodersen L, Tomizawa, D., Kolb, E.A., Reinhardt, D. (eds) Acute Myeloid Leukemia in Children, 2024
A Longitudinal Single-Cell Atlas of treatment Response in Pediatric AML
Lambo S, Trinh DL, Ries RE, Jin D, Setiadi A, Ng M, Leblanc VG, Loken MR, Eidenschink Brodersen L, Dai F, Pardo LM, Ma X, Vercauteren SM, Meshinchi S, Marra MA, Cancer Cell 41(12): 2117-2135, 2023, PMID:37977148
Comprehensive Molecular Characterization of NUP98 Fusions in Pediatric Acute Myeloid Leukemia
Tarlock K, Ostronoff F, Pogosova-Agadjanyan EL, Kaspers GJL, Hasle H, Dworzak M, Walter C, Muhlegger N, Morerio C, Pardo L, Hirsch B, Raimondi S, Cooper TM, Aplenc R, Gamis AS, Kolb EA, Farrar JE, Stirewalt D, Ma X, Shaw TI, Furlan SN, Eidenschink Brodersen L, Loken MR, Van den Heuvel-Eibrink MM, Zwaan CM, Triche TJ, Goemans BF, Meshinchi S., Haematologica 108(8): 2044-2058, 2023, PMID:36815378
The Impact of Down Syndrome-Specific Non-Malignant Hematopoietic Regeneration in the Bone Marrow on the Detection of Leukemic Measurable Residual Disease
Hsu FC, Hudson C, Wilson ER, Pardo LM, Singleton TP, Xu D, Zehentner BK, Hitzler J, Berman J, Wells DA, Loken MR, Eidenschink Brodersen L, Cytometry B Clin Cytom 104(4): 311-318, 2023, PMID:37015883
Preclinical Studies Targeting CD74 With STRO-001 Antibody-drug Conjugate in Acute Leukemia.
Le Q, Tang T, Leonti A, Castro S, McKay CN, Perkins L, Pardo L, Kirkey D, Hylkema T, Call L, Manselle M, Abrahams C, Bedard K, Molina A, Eidenschink Brodersen L, Loken MR, Tarlock K, Meshinchi S, Loeb KR, Blood Advances 7(9): 1666-1670, 2023, PMID:36595452
Therapeutic Targeting of PRAME with mTCR CAR T Cells in Acute Myeloid Leukemia
Kirkey DC, Loeb AM, Castro S, McKay CN, Perkins L, Pardo L, Leonti AR, Tang TT, Loken MR, Eidenschink Brodersen L, Loeb KR, Scheinberg DA, Le Q, Meshinchi S, Blood Advances 7(7): 1178-1189, 2023, PMID:35984639
Multiparameter Flow Cytometry in the Evaluation of Myelodysplasia: Analytical Issues: Recommendations From the European LeukemiaNet/International Myelodsyplastic Syndrome Flow Cytometry Working Group
Porwit A, Béné MC, Duetz C, Matarraz S, Oelschlaegel U, Westers TM, Wagner-Ballon O, Kordasti S, Valent P, Preijers F, Alhan C, Bellos F, Bettelheim P, Burbury K, Chapuis N, Cremers E, Della Porta MG, Dunlop A, Eidenschink Brodersen L, Font P, Fontenay M, Hobo W, Ireland R, Johansson U, Loken MR, Ogata K, Orfao A, Psarra K, Saft L, Subira D, Te Marvelde J, Wells DA, van der Velden VHJ, Kern W, van de Loosdrecht AA., Cytometry B Clin Cytom 104(1): 27-50, 2023, PMID:36537621
