Associate Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
413 BRB II/III, 421 Curie Blvd
Philadelphia, PA 19104
Office: 215-573-9704
Fax: 215-746-5511
Email: mhaldar@pennmedicine.upenn.edu
Research in our laboratory is at the intersection of innate immune system and solid tumor biology. Specifically, we study the mononuclear phagocyte system (MPS) with an emphasis on their role in the tumor microenvironment. MPS is part of the innate immune system and comprises of monocytes, macrophages, and dendritic cells (DC). These cells are functionally, phenotypically, and developmentally heterogeneous with many distinct subsets. We are interested in understanding the molecular basis of this developmental and functional heterogeneity within the MPS. A major focus in our laboratory is to understand the role of MPS within the microenvironment of a group of solid tumors known as sarcomas. DCs and macrophages are thought to play important role in cancer by modulating host-immune responses against the tumor cells, promoting metastasis, angiogenesis, etc. Additionally, the ability of these cells to regulate lymphocyte function makes them an important determinant in the success of cancer immunotherapy. Using a combination of advanced genetically engineered mouse models in conjunction with patient-derived samples, we aim to uncover the molecular pathways underlying tumor-MPS interaction with the overarching goal of targeting them for therapeutic purposes.
More Info
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
916B Abramson Research Center
3615 Civic Center Blvd.
Philadelphia, PA 19104-4318
Office: 215-590-8709
Fax: 215-590-7384
Email: whancock@pennmedicine.upenn.edu
Research Interests
Transplant immunobiology, inflammation and mechanisms of disease
More Info
Emeritus Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
S 34th St & Civic Center Blvd
Main Building, Suite 5NW15
Philadelphia, PA 19104
Office: 267-426-5504
Fax: 267-426-7783
Itmat Expertise
Developmental neuropathology
Malformations and peditatric degenerative disorders of the nervous sytem
More Info
PGY-3, Combined Anatomic Pathology & Clinical Pathology Program
Assistant Professor of Pathology and Laboratory Medicine in Pediatrics
Perelman School of Medicine at the University of Pennsylvania
Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
3401 Civic Center Blvd
5th Floor Main Building
Philadelphia, PA, 19104
More Info
Staff Pathologist, Rochester General Hospital, Rochester, NY
2016-17 Cytopathology Fellow, Hospital of the University of Pennsylvania
2015-16 Surgical Pathology Fellow
Hospital of the University of Pennsylvania
AP Chief Resident 2014
Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Abramson Research Bldg. 710B
The Children's Hospital of Philadelphia
3615 Civic Center Blvd.
Philadelphia, PA, 19104
Office: 267-426-7588
More Info
Physician, Chester County Hospital
Associate Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
The Institute for Immunology
Perelman School of Medicine at the University of Pennsylvania
421 Curie Boulevard
Biomedical Research Building II/III, Room 312
Philadelphia, PA, 19104
Email: jhena@pennmedicine.upenn.edu
More Info
Assistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Director, Endocrine Laboratory
Contact Information
3700 Hamilton Walk
Richards Building, B202
Philadelphia, PA 19104
Office: 215-662-6575
Fax: 215-662-7529
Email: daniel.herman2@pennmedicine.upenn.edu
Itmat Expertise
I am interested in leveraging existing clinical data and developing new biomarker-based strategies for screening for under diagnosed diseases, including causes of secondary hypertension.
More Info
Postdoctoral Researcher, Center for Personalized Diagnostics
Molecular Genetic Pathology Clinical Fellow
University of Pennsylvania
Combined Anatomic Pathology & Clinical Pathology Program
2020-21 Cytopathology Fellowship at UCSF
Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
3400 Spruce Street
6 Founders Pavilion – Room 6.085
Philadelphia, , 19104
Office: 2484203289
Email: tom.hu@pennmedicine.upenn.edu
More Info
Wistar Institute Professor of Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine
Contact Information
Immunology, Microenvironment & Metastasis Program, Wistar Institute, Room 430, 3601 Spruce Street
Philadelphia, PA, 19104-4265
Office: 215-495-6976
Research Expertise
Research Interest:
The biology of the endoplasmic reticulum in health and disease
Keywords:
Endoplasmic reticulum (ER); B cell; protein folding and assembly; glycosylation; membrane protein trafficking
Research Details:
More Info
Associate Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Pennsylvania Hospital
801 Spruce Street
Room SP-1020
Philadelphia, PA 19107
Office: 215-829-5443
Fax: 215-829-7564
Email: huangju@pennmedicine.upenn.edu
Research Expertise
Translational research questions related to mechanisms of sarcomagenesis. Co-inventor of "cell paint" / Trans signal conversion.
More Info
Senior Director for Clinical Services, Pennsylvania Hospital
Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Vice Chair, Pathology, Pennsylvania Hospital
Laboratory Director, Penn Medicine Valley Forge
Combined Anatomic Pathology & Clinical Pathology Program
2023-24 Cytopathology Fellow, HUP