Molecular Genetic Pathology


Molecular Genetic Pathology (MGP) is the subspecialty of Pathology and Medical Genetics in which the principles, theory, and technologies of molecular biology and molecular genetics are applied to help diagnose disease, determine prognosis, monitor infections and treatment, and assess risk for genetic disorders.  Overtime, MGP continues to grow increasingly essential to the practice of medicine. At the Penn Department of Pathology and Laboratory Medicine, MGP has been recognized as an integral part of modern medical practice since 1985, when the Molecular Pathology Laboratory was founded as one of the first of its kind at a university hospital in the country. Likewise, Penn was among the first training programs in the country in the early 1990s and one of the first two programs to obtain ACGME accreditation in 2002 when MGP became a recognized subspecialty.


The goal of the Penn MGP program is to train fellows in the practice of molecular genetic pathology, the application and interpretation of molecular laboratory techniques, and diagnostic laboratory administration. Over the course of the one-year ACGME accredited fellowship, the fellow gains experience in the application of molecular genetic pathology through service work, didactic lectures, resident teaching, involvement in laboratory administration, and hands-on test development and/or research projects through rotations at the Hospital of the University of Pennsylvania (HUP) and the Children’s Hospital of Philadelphia (CHOP). Fellows are exposed to clinical genetics through rotations in pediatric and adult clinical genetics and biochemical genetics. At the completion of the fellowship, the trainee will be eligible to take the Molecular Genetic Pathology Board examination.


Up to three MGP fellowship positions are available each year. Candidates must be Board-eligible in either AP and/or CP or Medical Genetics and have passed the USMLE Part 3 exam prior to the start of the program. They must also be licensed or eligible for licensure in Pennsylvania. Prior experience in genetics and/or molecular biology is recommended.

Each academic year begins on the first of July. Applications will be accepted beginning July 1, through December 31st, 18-24 months prior to the anticipated start of the program. Offers of a position are given on a rolling basis after the start of interviews; therefore, we encourage applicants to submit their applications early, as there is no guarantee that a position will remain available. Candidates considered for the program will be asked to interview.

Key Program Faculty

Division of PCD
Christopher Watt, MD, PhD
Guang (Geoff) Yang, MD, PhD
Jacquelyn Roth, PhD
Jennifer Morrissette, PhD
Malay Haldar, MD, PhD
Salvatore Priore, MD, PhD
Vivianna Van Deerlin, MD, PhD
Warren Pear, MD, PhD

Laurel Glaser, MD
Kyle Rodino, PhD

Lea Surrey, MD
Minjie Luo, PhD