Brad Johnson, MD, PhD, is co-senior author of a study published in Cell Stem Cell that has found a link between telomeres and a molecular signaling cascade called the Wnt pathway that may point to a treatment option for the rare, inherited disease Dyskeratosis congenita (DC). The paper, "Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita,"  also provides insights into strategies to combat telomere dysfunction, a process that has also been implicated in some cancers and natural aging.
Read the University of Pennsylvania news release.