Pathology & Laboratory Medicine Research Day 2022
September 26, 2022
Tuesday, October 25, 2022
8 AM to 3 PM
Biomedical Research Building (BRB II/III) - Glen Gaulton Auditorium
421 Curie Boulevard
Philadelphia, PA 19104
Please join us for this year's Pathology and Laboratory Medicine Research Day! Faculty, staff and trainees will come together to showcase the exciting research being conducted at Penn. This year's event will feature lectures by faculty and fellows as well as poster presentations.
8:00 AM Breakfast Served
8:30 AM David Roth, MD, PhD
Opening remarks
8:40 AM Silvia Porta, PhD
"Biochemical and molecular heterogeneity of human TDP-43 proteinopathies in age-related dementias"
9:05 AM MacLean Nasrallah, MD, PhD
"Can You Train a Machine in Neuropathology"
9:30 AM Michael Feldman, MD, PhD
Keynote Address: "Digital Pathology and Integrated Diagnostics"
10:15 AM Morning Break and Refreshments
10:45 AM Kyle Rodino, PhD
"SARS-CoV-2 Genomic Surveillance in the Delaware Valley: A Penn Medicine Clinical and Academic Lab Partnership"
11:10 AM Sydney Shaffer, MD, PhD
"Unraveling single-cell clonal dynamics in Barrett's esophagus"
11:35 AM Robert Faryabi, PhD, MSC
"Role of Lineage Switching in T Cell Leukemia Therapy Resistance"
12:00 PM Lunch Served and Poster Session
1:30 PM Malay Haldar, MD, PhD
"Antigen presenting cells in the tumor microenvironment"
1:55 PM Jina Ko, PhD
"Single Cell and Extracellular Vesicle Profiling for Molecular Diagnostics"
2:20 PM Nicole Aqui, MD
Announcement of poster session winners and closing remarks
Poster Presentations
| Basic and Computational Research | Clinical Translational Research | |
| Alexander Smith Microbial Cooperation Enhances Clostridioides difficile Pathogenesis |
Ashley Ginda Increased T Cell Turnover in Sickle Cell Disease |
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| Alfonso Oceguera Tracking HIV Clones: The Barcode Project |
Austin Good Utilizing data from fusion transcript analysis by massively parallel sequencing beyond validated gene fusion reporting |
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| Ashkan Bigdeli Azurify: Pathogenicity Classification of Somatic Mutations in Clinical Diagnostics Through Online Machine Learning |
Bhakti Baheti AI-based Prognostic Stratification of Glioblastoma using Hematoxylin & Eosin-Stained Whole Slide Images |
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| Brent Perelman Differential 3D clique analysis: Genome-wide screen to identify epigenetic drivers of disease |
Christopher Sande Genetic Drivers of Clonal Hematopoiesis in Patients with Telomere Biology Disorders |
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| Carolina Gracia Diaz Mutations in PRC2 histone methyltransferase EZH1 disrupt neuronal differentiation and lead to neurodevelopmental disorders |
Courtney Comar Evaluation of a Novel Sample Preparation Workflow for Rapid Identification and Phenotypic Susceptibility Testing of Gram-negative Bacilli Directly from Blood Cultures |
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| Charlotte Kearns In vivo and in vitro evidence for infection of naïve CD4 T cells with CCR5-tropic HIV |
Emily Ling-Lin Pai Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters (DGONC) – A Novel Pediatric Brain Tumor Entity |
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| Diana Lazaro Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain |
Farah El-Sharkawy Navarro A Recurrent ERBB2 Rearrangement in Invasive Mucinous Adenocarcinoma of the Lung |
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| James Knox Splenic T-bet+ B cells exhibit stem-like features and constitutively generate antibody-secreting cells |
James Corines Gene-Specific Validation of Copy Number Gains from a Massively Parallel Sequencing Assay |
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| Jingru Zhao Optical Mapping of Genome Organization Identifies 3D Enhancer Hubs in TNBC |
Joseph Kim Unique Epidemiologic Features of Esophageal Squamous Dysplasia: A Retrospective Single Institution Study |
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| Kelly Fagan Gene Editing Strategies to Treat Spinocerebellar Ataxia Type 1 |
Sarthak Pati Leveraging Federated Learning to Train Clinically Relevant Models |
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| Mayassa Bou-Dargham TRIB1 regulates neutrophil development and function |
Serena Walker The Floating Imposter: A Patient Safety Collaboration between Anatomic and Molecular Pathology |
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| Nilanjana Samanta PANC-DB: Data Repository of Human Pancreas Analysis Program (HPAP) |
Stefen Andrianus Effectiveness and Utility of IHC Staining in Mild Chronic Gastritis in Detection of H. pylori Organisms: Practice Trends in General Pathologists and GI Pathologists |
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| Po Hu Single-cell Genomics Study of Fontan-associated Liver Disease |
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| Rebecca Ramesh CNViz:an R/Shiny Application For Interactive Copy Number Variant Visualization in Cancer |
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| Roshan Pillai Reprogramming CAR T Cells with Mutated IDH1 Enhances The Therapeutic Potential of CAR T Cells in Solid Tumors |
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| Terry Chang To Supervise or Not to Supervise: A Perception of Microscopic Transition to the FDA Approved Automated Screening Method in the Field of Artificial Intelligence and Pathology |
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| Vanessa Sanchez Uncovering mechanisms of SNX13-SNX14 interaction in cerebellar function and disease |
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| William Molina Iron rich tumor associated macrophages promote tumor growth and immune suppression |
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| Yeqiao Zhou EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells |
Registration Details
Registration for Research Day 2022 closed on October 19th, 2022.