PEOPLE

Jacquelyn Roth, Ph.D., DABMGG

Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information3400 Spruce Street
7.103 Founders Pavilion
Philadelphia, PA, 19104

Specialty Division

Precision and Computational Diagnostics

Education

BA (Major - Biology, Minor - Applied Mathematics), Franklin & Marshall College, 2004
PhD (Genetics), Thomas Jefferson University, 2011

Specialty Certification

American Board of Medical Genetics and Genomics, Clinical Cytogenetics, 2013
American Board of Medical Genetics and Genomics, Clinical Molecular Genetics, 2015

Postgraduate Training

ABMGG Fellowship, Clinical Cytogenetics, The Children's Hospital of Philadelphia, 2011-2013
ABMGG Fellowship, Clinical Molecular Genetics, The Children's Hospital of Philadelphia, 2013-2014

Awards and Honors

John Marshall Scholar, Franklin and Marshall College, 2000-2004
Howard Hughes Scholar, Franklin and Marshall College, 2001-2004
Alpha Epsilon Delta Premedical Honor Society, Franklin and Marshall College, 2003-2004
Biology Departmental Honors, Franklin and Marshall College, 2004
M. Munson Award in Dance, Franklin and Marshall College, 2004
Marie D’Agostino Senior Biology Award, Franklin and Marshall College, 2004
NIH Training Grant, Thomas Jefferson University, 2006-2009
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2008
The Fredric Rieders Renaissance Foundation Graduate Student Recognition Award, Thomas Jefferson University, 2011
Mouse Genetics Travel Scholarship, International Mammalian Genome Conference, 2011
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2011
Cis B. Golder Quality of Life Grant, Living Beyond Breast Cancer, 2011
Jefferson College of Graduate Studies Alumni Prize for Best Thesis, Thomas Jefferson University, 2012
Spirit of the Promise Award, Susan G. Komen Philadelphia, 2012
Student Travel Award, American Cytogenetics Conference, 2012
Going Beyond Award, Living Beyond Breast Cancer, 2012
Research Poster Day Prize, The Children’s Hospital of Philadelphia, 2014

Memberships and Professional Organizations

American Association for the Advancement of Science, 2007 - 2009
The American Society for Cell Biology, 2008 - 2009
Young Survival Coalition, 2010 - 2014
Living Beyond Breast Cancer, 2010 - Present
Susan G. Komen for the Cure Philadelphia, 2010 - 2016
National Post-Doctoral Association, 2011 - 2014
American Cytogenetics Conference, 2012 - Present
Association for Molecular Pathology, 2014 - Present
College of American Pathologists (Member and Site Inspector), 2016 - Present

Web Links


Selected Publications

Clinical, Educational, and Financial Impact of a Standardized Workflow for Salvaging Quality and Quantity Not Sufficient (QNS) Samples in an Academic NGS Laboratory

Priore, S.F., Lieberman, D., Milano, J.R., Sussman, R.T, Rosenbaum, J.N., and Roth, J.J., Presented at the United States & Canadian Academy of Pathology Annual Meeting, National Harbor, MD, 2019.

AMP Case Report: Diagnostic Pitfalls of Opportunities and Challenges of Molecular Testing Rare Molecular Aberrations in Lung Adenocarcinomas.

Priore Salvatore F., Rosenbaum Jason N., and Roth Jacquelyn J., CAP Today. 33(2): 26-28, 2019.

Virtual case sets for genomics education: thinking outside the slide box

Rosenbaum, J.N., Roth, J.J., Lieberman, D.B., Orr, C., Deihimi, S., and Morrissette, J.J., J Mol Diagn 20(6): 967, 2018.

Suitability of formical-2000 decalcified paraffin embedded tissue for fluorescence in situ hybridization (FISH) and next generation sequencing (NGS)

Lieberman, D., Aikawa, V., Oran, A.R., Roth, J.J., Rosenbaum, J.N., and Sussman, R.T., J Mol Diagn 20(6): 1030, 2018.

Interpretation of mutational signatures associated with smoking from an amplicon-based clinical oncology sequencing panel

Adler, J.E., Shaffer, S., Roth, J.J., and Rosenbaum, J.N., J Mol Diagn 20(6): 959, 2018.

Optimizing RNA extraction to facilitate BCR/ABL1 quantitative testing

Belman, J., Gentile, C., Lake, J., Roth, J., and Watt, C., J Mol Diagn 20(6): 1031, 2018.

Validation of a low input targeted NGS assay for lymphoma across multiple specimen types

Oran, A., Paolillo, C., Deihimi, S., Lieberman, D.B., Bigdeli, A., Chitturi, A., Roth, J.J., Rosenbaum, J., Morrissette, J.J., and Sussman, R.T., J Mol Diagn 20(6): 923, 2018.

Standardized protocol for salvaging quality or quantity not sufficient (QNS) samples in an academic NGS laboratory

Priore, S.F., Lieberman, D., Milano, J.R., Sussman, R.T., Rosenbaum, J.N., and Roth, J.J., J Mol Diagn 20(6): 967, 2018.

Discordance among biomarkers for Anti-PD1 therapy response: tumor mutational burden and anti-PD-L1 staining

Hess, P.R., Velu, P.D., Bigedli, A., Morrissette, J.J.D., Rosenbaum, J.N. and Roth, J.J., J Mol Diagn 19(6): 1039, 2017.

Calculation of mutational burden in a clinical targeted next-generation sequencing (NGS) panel for solid tumors

Velu, P.D., Bigedli, A., Hess, P., Roth, J.J., Rosenbaum, J., and Morrissette, J.J.D., J Mol Diagn 19(6): 1024, 2017.