Jacquelyn Roth, PhD, DABMGG

Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information3400 Spruce Street
7.103 Founders Pavilion
Philadelphia, PA, 19104

Specialty Division

Precision and Computational Diagnostics


BA (Major - Biology, Minor - Applied Mathematics), Franklin & Marshall College, 2004
PhD (Genetics), Thomas Jefferson University, 2011

Specialty Certification

American Board of Medical Genetics and Genomics, Clinical Cytogenetics, 2013
American Board of Medical Genetics and Genomics, Clinical Molecular Genetics, 2015

Postgraduate Training

ABMGG Fellowship, Clinical Cytogenetics, The Children's Hospital of Philadelphia, 2011-2013
ABMGG Fellowship, Clinical Molecular Genetics, The Children's Hospital of Philadelphia, 2013-2014

Awards and Honors

John Marshall Scholar, Franklin and Marshall College, 2000-2004
Howard Hughes Scholar, Franklin and Marshall College, 2001-2004
Alpha Epsilon Delta Premedical Honor Society, Franklin and Marshall College, 2003-2004
Marie D’Agostino Senior Biology Award, Franklin and Marshall College, 2004
Biology Departmental Honors, Franklin and Marshall College, 2004
M. Munson Award in Dance, Franklin and Marshall College, 2004
NIH Training Grant, Thomas Jefferson University, 2006-2009
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2008
Cis B. Golder Quality of Life Grant, Living Beyond Breast Cancer, 2011
Mouse Genetics Travel Scholarship, International Mammalian Genome Conference, 2011
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2011
The Fredric Rieders Renaissance Foundation Graduate Student Recognition Award, Thomas Jefferson University, 2011
Student Travel Award, American Cytogenetics Conference, 2012
Jefferson College of Graduate Studies Alumni Prize for Best Thesis, Thomas Jefferson University, 2012
Going Beyond Award, Living Beyond Breast Cancer, 2012
Spirit of the Promise Award, Susan G. Komen Philadelphia, 2012
Research Poster Day Prize, The Children’s Hospital of Philadelphia, 2014

Memberships and Professional Organizations

American Association for the Advancement of Science, 2007 - 2009
The American Society for Cell Biology, 2008 - 2009
Living Beyond Breast Cancer, 2010 - 2019
Susan G. Komen for the Cure Philadelphia, 2010 - 2016
Young Survival Coalition, 2010 - 2014
National Post-Doctoral Association, 2011 - 2014
American Cytogenetics Conference, 2012 - Present
Association for Molecular Pathology, 2014 - Present
College of American Pathologists, 2016 - Present
National Cancer Institutes Funded Grant of Drs. Kate Nathanson and Steve Joffe, 2019 - Present

Web Links

Selected Publications

Optimization of Sources of Circulating Cell-Free DNA Variability for Downstream Molecular Analysis

Jacob E.Till, Taylor A.Black, Caren Gentile, Aseel Abdalla, Zhuoyang Wang, Hareena K.Sangha, Jacquelyn J.Roth, Robyn Sussman, Stephanie S.Yee, Mark H.O'Hara, Jeffrey C.Thompson, CharuAggarwal, Wei-Ting Hwang, Kojo S.J.Elenitoba-Johnson, Erica L.Carpenter, J. Mol. Diag. 23(11): 1545-52, 2021, PMID:34454115

Read article

AMP Case Report: Role of lymphoma sequencing panel in diagnosis of pediatric-type follicular lymphoma

Guang Yang, Gabriel C. Caponetti, Jacquelyn J. Roth, Kojo S. Elenitoba-Johnson, Megan S. Lim, CAP Today, 2020

Economic, Operational, and Clinical Considerations in Deploying Rapid NGS for Lung Cancer

Sande, C., Madrigal, A., Roth, J. J., Rosenbaum, J., Elenitoba-Johnson, K., Milano, J., J Mol Diagn 22(11): S57, 2020

Educating in a Pandemic: Rapid Changes to Molecular Genetic Pathology Graduate Medical Education Training during COVID-19

El-Sharkawy Navarro, F., Davis, A., Yoon, J. Y., Garces-Narvaez, S., Roth, J. J., Priore, S., J Mol Diagn 22(11): S57, 2020

The role of fluorescence-in-situ hybridization in identifying targetable NUP214-ABL1 fusion in a T-lymphoblastic leukemia

Lee, W. S., Roth, J. J., Morrissette, J. J. D., Aikawa, V. N., Bhattacharyya, S., Lim, M. S., Elenitoba-Johnson, K., Association for Molecular Pathology (AMP), 2020

Rapid fluorescence in situ hybridisation optimises induction therapy for acute myeloid leukaemia

Nya D. Nelson, Christine M. McMahon, Craig W. Freyer, Jacquelyn J. Roth, Selina M. Luger, Adam Bagg, Jennifer J.D. Morrissette, British Journal of Haematology, 2020, PMID:33460058

Read article

Case Presentation at Diagnostic Slide Show 2020

Kolster, R. A., Roth, J. J., Surrey, L., Nasrallah, M., American Association of Neuropathologists Annual Meeting, 2020

Compound EGFR and BRAF variants in NSCLC against the backdrop of suspected MEN2A

Adler, J.E., Rosenbaum, J.N., and Roth, J.J., Association for Molecular Pathology (AMP), 2019

Reporting Indeterminate Variants from Massively Parallel Sequencing Assays

Roth, J.J., Lieberman, D., Orr, C.R., Deihimi, S., Herzog, C.R., Elenitoba-Johnson, K.S., Morrissette, J.J., and Rosenbaum, J.N., J Mol Diagn 21(6): 1180, 2019

Measuring Yield and Variation: Evaluation of Plasma Circulating Cell-Free DNA Extraction and Measurement Methods

Till, J.E., Black, T.A., Gentile, C., Roth, J.J., Sussman, R.T., Mays, J.J., Wang, Z., Sangha, H.K., Chang, R.B., Yee, S.S., Elenitoba-Johnson, K.S., and Carpenter, E.L., J Mol Diagn 21(6): 1235, 2019