PRECISION AND COMPUTATIONAL DIAGNOSTICS

Cytogenetics

The Philadelphia Chromosome, first described by Department member Peter Nowell and named after its place of discovery, provided the first evidence that genetic abnormalities were linked to cancer. This discovery at Penn more than 50 years ago ushered in the modern period of cytogenetics. Now, the Center for Personalized Diagnostics (CPD), founded in 2013, builds on this legacy and is set to pave the way for a new era of genomic and therapeutic pathology.

The Cytogenetics Laboratory, as part of the CPD, performs chromosome analysis in diagnosing and classifying leukemias and other hematologic disorders under the direction of Megan Lim, MD, PhD, Medical Director, and Jennifer Morrissette, PhD, Scientific Director.

The CPD, a joint initiative between Penn Medicine's Department of Pathology and Laboratory Medicine and the Abramson Cancer Center, integrates Molecular Genetics, Pathology Informatics, and Genomic Pathology for individualized patient diagnoses and to elucidate cancer treatment options for physicians. The CAP/CLIA-certified CPD enables precision therapies by offering genome-wide diagnostics to identify the specific tumor characteristics for each patient.

More information on the Center for Personalized Diagnostics.


find a Specialist
Cytogenetics
Megan S. Lim, MD, PhD

Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania

University of Pennsylvania Perelman School of Medicine

Director, Hematopathology


Adam Bagg, MD

Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania

University of Pennsylvania Perelman School of Medicine


Jennifer J.D. Morrissette, PhD

Associate Professor of Clinical Pathology and Laboratory Medicine

Clinical Director, Center for Personalized Diagnostics

University of Pennsylvania Perelman School of Medicine


Avni B. Santani, PhD

Assistant Professor of Clinical Pathology and Laboratory Medicine

University of Pennsylvania Perelman School of Medicine