Jennifer J.D. Morrissette, PhD

Associate Professor of Clinical Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics
University of Pennsylvania Perelman School of Medicine

Contact InformationDepartment of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-898-5578
Fax: 215-898-9817


Specialty Division

Precision and Computational Diagnostics


B.S. (Molecular Biology), State University of New York at Buffalo, 1986
Ph.D. (Molecular Genetics), State University of New York at Buffalo, 1992

Specialty Certification

American Board of Medical Genetics, Clinical Molecular Genetic Diagnostics, 2002
American Board of Medical Genetics, Clinical Cytogenetics, 2002
New York State Certificate of Qualification,
Cytogenetics and Molecular Genetic Diagnostics, 2004

Postgraduate Training

Postdoctoral Fellow, Molecular Genetics, Department of Pathology, Harvard Medical School, Boston MA, 1992-1997
Fellow in Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1998-2002

Awards and Honors

Mark Diamond Initiative Award, Department of Biological Sciences, State University of New York at Buffalo, 1990
NIH Intramural Research Training Award fellowship, 1992-1993
Pathobiology of Cancer: The Edward A. Smuckler Memorial Workshop, Keystone Colorado, American Association of Cancer Research, 1992
American Social Health Association/Burroughs Wellcome Fund Research Fellowship, 1994-1996
American Association of Cancer Research Fellowship, 1996-1997
General Clinical Research Center (GCRC). Children’s Hospital of Philadelphia, Investigator, 2001-2005
Foerderer Fund for Excellence, Molecular and Cytogenetic Analysis of Autism, 2003-2004
Peter C. Nowell Award in Pathology, University of Pennsylvania, 2013

Memberships and Professional Organizations

American Society Human Genetics, 1998 - 2020
Philadelphia Genetics Group, 2004 - 2018
American College of Medical Genetics, 2005 - Present
American Cytogenetics Conference, 2006 - Present
Children’s Oncology Group, 2007 - 2011
Continuing Education for Cytogenetic Technologists, American Society of Clinical Pathology, 2010 - 2012
Association of Molecular Pathology, 2011 - Present
Novitas Molecular Reimbursement Academic Consortium, 2012 - 2014
Eastern Cooperative Oncology Group (ECOG), 2014 - Present
Genomics Organization for Academic Laboratories (GOAL), 2017 - Present
American Board of Medical Genetics and Genomics (ABMGG), 2017 - 2020
American Society for Clinical Pathology (ASCP) Immuno-Oncology Working Group, 2018 - 2020
International Foundation of Clinical Chemistry and Laboratory Medicine (IFCC)., 2019 - Present

Web Links

Selected Publications

T-cell Lymphoma and Secondary Primary Malignancy Risk After Commercial CAR T-cell Therapy

Ghilardi G, Fraietta JA, Gerson JN, Van Deerlin VM, Morrissette JJD, Caponetti GC, Paruzzo L, Harris JC, Chong EA, Susanibar Adaniya SP, Svoboda J, Nasta SD, Ugwuanyi OH, Landsburg DJ, Fardella E, Waxman AJ, Chong ER, Patel V, Pajarillo R, Kulikovskaya I, Lieberman DB, Cohen AD, Levine BL, Stadtmauer EA, Frey NV, Vogl DT, Hexner EO, Barta SK, Porter DL, Garfall AL, Schuster SJ, June CH, Ruella M., Nat Med., 2024, PMID:38266761

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TP53 mutations predict for poor outcomes in patients with newly diagnosed aggressive B-cell lymphomas in the current era.

Landsburg DJ, Morrissette JJ, Nasta SD, Barta SK, Schuster SJ, Svoboda J, Chong EA, Bagg A., Blood Adv. 7(): 7243-7253, 2023, PMID:37851898

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Impact of Genetic Mutations on Survival Following Receipt of commercial CART19 for Patients Diagnosed with Aggressive B Cell Lymphoma

Frost BF, Morrissette JJD, Shuster SJ, Nasta SD, Svoboda J, Barta SK, Elise A. Chong3, Ruella M, Bagg A, Landsburg DJ, American Society of Haematology (ASH) Annual meeting, 2023

Somatic Mutation Screening in Adult Patients with Myeloid Malignancies Provides Insights into Likely Germline Variants.

Bhansali1 RS, Wang X, Mattfield V, Clark D, Morrissette JJD, Babushok D, Carroll M, Bruno XJ, American Society of Haematology (ASH) Annual meeting, 2023

DNA Damage Response Constrains Cell Growth and Drives Clonal Hematopoiesis in Telomere Biology Disorders

Sande CM, Chen S, Mitchell DV, Lin P, Deolikar RJ, Freeman C, Zhou M, Zheng S, Munkhbileg B, Stanley NL, Guo K, Hausler R, Taylor D, Corines J, Morrissette JJD, Lieberman DB, Yang G, Nicholas P, Dokal I, Rosenheck J, Churpek J, Johnson FB, Olson TS, Babushok DV, American Society of Haematology (ASH) Annual Meeting, 2023

CDH1 is an Uncommon but Recurrent Tumor Suppressor Gene Mutated in Advanced Prostate Cancer

Poveda-Rogers C, Ni V, Corines J, Morrissette JJD, Yang G, Association for Molecular Pathology (AMP) annual meeting, 2023

Features of Loss-of-Function SYK-Mutated Advanced Melanoma.

Poveda-Rogers C, Ni V, Corines J, Morrissette JJD, Yang G, Association for Molecular Pathology (AMP) annual meeting, 2023

The Genomics Organization for Academic Laboratories (GOAL): A vision for a genomics future for academic pathology

Aisner DL, Gocke CD, Jones D, Limson M, Morrissette J, Segal JP., Acad Pathol. 10(): , 2023, PMID:37583476

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ROS1 alterations as a potential driver of gliomas in infant, pediatric, and adult patients

Meredith DM, Cooley LD, Dubuc A, Morrissette J, Sussman RT, Nasrallah MP, Rathbun P, Yap KL, Wadhwani N, Bao L, Wolff DJ, Ida C, Sukhanova M, Horbinski C, Jennings LJ, Farooqi M, Gener M, Ginn K, Kam KL, Sasaki K, Kanagal-Shamanna R, Alexandrescu S, Brat D, Lu X., Mod Pathol. 36(11): 100294, 2023, PMID:37532182

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Homologous recombination pathway gene variants identified by tumor-only sequencing assays in lung carcinoma patients

Yoon JY, Roth JJ, Rushton CA, Morrissette JJD, Nathanson KL, Cohen RB, Rosenbaum JN., Transl Lung Cancer Res. 12(): 1236-1244, 2023, PMID:37425424

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