Update on Antibody Testing for SARS-CoV-2/ COVID-19

Penn Medicine has different serologic tests for SARS-CoV-2 virus that are orderable in Penn Chart. The newest addition to the antibody testing category is a test to measure receptor binding domain (RBD) IgG and RBD IgA antibodies. This post outlines the types of SARS-CoV-2 antibody testing available, when it may be appropriate to order such testing, and how to interpret the results.

Pathology & Laboratory Medicine Update on COVID-19 Testing

Below is the most recent announcement regarding COVID-19 from the Department of Pathology & Laboratory Medicine.

Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1

Rodino KG, Peaper DR, Kelly BJ, Bushman F, Marques A, Adhikari H, Tu ZJ, Marrero Rolon R, Westblade LF, Green DA, Berry GJ, Wu F, Annavajhala MK, Uhlemann AC, Parikh BA, McMillen T

Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

Research led by Sara Cherry, PhD, of Pathology and Laboratory Medicine, with David Schultz, PhD, technical director of the High-Throughput Screening Core, identified a powerful combination of antiv

A randomized controlled study of convalescent plasma for individuals hospitalized with COVID-19 pneumonia