Pathology & Laboratory Medicine Update on COVID-19 Testing

Below is the most recent announcement regarding COVID-19 from the Department of Pathology & Laboratory Medicine.

Updated Provider Guidance on Serologic Testing for SARS-CoV-2

The Clinical Immunology and Clinical Core labs at the Hospital of the University of Pennsylvania have discontinued serologic testing for SARS-CoV-2. The two tests that were previously performed, COVID-19 (SARS-CoV-2) antibodies (Anti-Nucleocapsid IgG Antibody) and SARS-CoV-2 Serology, antibodies, immunoassay (RBD assessment), are no longer available as in-house assays.

Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1

Rodino KG, Peaper DR, Kelly BJ, Bushman F, Marques A, Adhikari H, Tu ZJ, Marrero Rolon R, Westblade LF, Green DA, Berry GJ, Wu F, Annavajhala MK, Uhlemann AC, Parikh BA, McMillen T

Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

Research led by Sara Cherry, PhD, of Pathology and Laboratory Medicine, with David Schultz, PhD, technical director of the High-Throughput Screening Core, identified a powerful combination of antiv

A randomized controlled study of convalescent plasma for individuals hospitalized with COVID-19 pneumonia