Pathology & Laboratory Medicine Update on COVID-19 Testing

Below is the most recent announcement regarding COVID-19 from the Department of Pathology & Laboratory Medicine.

Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion

Study Finds Immune System Protein Prompts Obese Mice to 'Sweat' Out Fat

Kambayashi Lab study in Science finds that mice engineered to produce elevated TSLP cytokine displayed selective white adipose tissue loss that protected them from obesity, insulin resistance, and steatohepatitis.

Cherry Lab Discovers Drug that Blocks Multiple SARS-CoV-2 Variants in Mice

The drug diABZI — which activates the body’s innate immune response — was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2.

Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau

New, Rare Genetic Form of Dementia Discovered by Edward Lee Lab

Paper in Science describes novel autosomal dominant dementia called Vacuolar Tauopathy (VT).