The Clinical Microbiology Laboratory offers diagnostic testing and consultative services for infectious diseases caused by bacteria, mycobacteria, fungi, viruses, and parasites. In addition, it performs antimicrobial and antifungal susceptibility testing when indicated to help guide anti-infective therapy. Staffed by three nationally recognized doctoral-level directors, it is arguably the most comprehensive diagnostic microbiology laboratory in the region. Its leaders, specially trained and board certified in Clinical Microbiology and Internal Medicine (Infectious Diseases), provide expert laboratory consultations. Accredited fellowships are available for sub-specialty training in Clinical Microbiology. Faculty conduct federally and privately funded research programs in their areas of expertise.

Providing full laboratory services in the above areas on a 24/7 basis, this laboratory’s outstanding technologist staff also displays great depth in detecting antimicrobial resistance; diagnosing Legionnaires’ disease and other respiratory tract infections as well as gastrointestinal tract infections; and detecting and identifying mycobacteria and fungi. Its staff work closely with faculty and staff in the Molecular Pathology Laboratory to develop new molecular-based approaches for diagnosing infectious disease. Clinical consultation is available at all times.


• Utilizes state-of-the-art technologies for rapid and accurate diagnosis of infectious diseases
• Identifies slow-growing and difficult-to-identify microorganisms by 16S rRNA gene sequence analysis on a routine basis
• Has special expertise in antimicrobial susceptibility testing and detection of novel resistance patterns
• Provides expert clinical staff consultations
• Supports clinical trials involving infectious disease testing

find a Specialist
Paul H. Edelstein, MD

Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania

University of Pennsylvania Perelman School of Medicine

Director, Clinical Microbiology Laboratory

Laurel J. Glaser, MD, PhD, D(ABMM)

Associate Professor of Clinical Pathology and Laboratory Medicine

Perelman School of Medicine at the University of Pennsylvania 

Director, Clinical Microbiology Laboratory

Co-Director, HUP/CHOP Fellowship in Clinical Microbiology

Associate Program Director for Clinical Pathology, HUP Pathology Residency Program

Irving Nachamkin, DrPH, MPH, D(ABMM), FAAM, FIDSA

Emeritus Professor of Pathology and Laboratory Medicine 

Perelman School of Medicine at the University of Pennsylvania

Kyle G. Rodino, PhD, D(ABMM)

Assistant Professor of Clinical Pathology and Laboratory Medicine

Perelman School of Medicine at the University of Pennsylvania

Assistant Director, Clinical Microbiology Laboratory

Director, Rittenhouse Molecular Laboratory 

Co-Director, Clinical Microbiology Fellowship Program

Hospital of the University of Pennsylvania