Allman Lab
Mechanisms underlying differentiation within the B cell lineage
Principal Investigator: David Michael Allman, PhD
Argon Lab
Functions of molecular chaperones in modulating cell surface receptors and secreted proteins
Principal Investigator: Yair Argon, PhD
Bassing Lab
DNA repair, genomic instability, cancer, lymphocyte development, V(D)J recombination, class switch recombination, auto-immunity
Principal Investigator: Craig H. Bassing, PhD
Brunden Lab
Identification of therapeutic targets and treatments for Alzheimer's, Parkinson's and other neurodegenerative diseases. This research encompasses target validation, in vitro assay development and optimization, high-throughput compound screening (HTS), and in vivo compound assessment, including pharmacokinetic and pharmacodynamic analyses, safety pharmacology and efficacy testing in neurodegenerative disease models. In addition, we conduct translational research studies to identify new potential drug targets for these neurodegenerative diseases.
Burkhardt Lab
Regulation of cytoskeletal dynamics in T cells and dendritic cells, and cytoskeletal control of the immune response
Principal Investigator: Janis K. Burkhardt, PhD
Cancro Lab
The Cancro laboratory is currently pursuing studies focused on mechanisms of B cell homeostasis and how these impact autoimmunity and aging. These have led to the characterization of a novel receptor for BLyS, a TNF family member that controls B cell numbers and determines the stringency of B cell selection.
Principal Investigator: Michael Cancro, PhD
Chen Lab
Gene therapy, autoimmune diseases, cancer, immunity, inflammation, apoptosis, and therapeutics
Principal Investigator: Youhai H. Chen, MD, PhD
Cherry Lab
The Cherry Lab is interested in emerging and globally important arthropod-borne viruses including the three major families that infect humans: the flaviviruses, alphaviruses and bunyaviruses. The Lab uses chemical and genetic screening technologies to perform a wide array of cell-based screens in human and insect cells studying emerging RNA viruses.
Principal Investigator: Sara Cherry, PhD
Choi Lab
Molecular analysis of the osteoimmune system
Principal Investigator: Yongwon Choi, PhD
Chou Lab
Mechanisms underlying malignant transformation
Principal Investigator: Margaret M. Chou, PhD
Cines Lab
Thrombosis, fibrinolysis, vascular biology, immunohematology
Principal Investigator: Douglas Cines, MD
Davies Lab
Biomechanics in Vascular Biology/Pathology, Hemodynamics and Atherosclerosis, Stents, Cytoskeletal and membrane biophysics
Principal Investigator: Peter F. Davies, PhD
Deng Lab
Development and application of new technologies for spatial omics profiling at the cellular level, specifically tools at the intersection of microchip, microscopy, genomics, and computational analysis to profile genome, epigenome, transcriptome, and proteome within the spatial context of tissues and cells.
Principal Investigator: Yanxiang Deng, PhD
Doms Lab
Research in the Doms lab utilizes a wide array of cell biological, biochemical, genetic, and immunological techniques to study membrane proteins important in HIV/AIDS pathogenesis as well as relatively new research projects on Rift Valley Fever virus and other members of the bunyavirus family in which we seek to identify host cell pathways that are used by these viruses to infect cells.
Principal Investigator: Robert W. Doms, MD, PhD
Eisinger Lab
The role of the Hippo pathway in soft tissue sarcomas; Mechanisms of sarcoma metastasis
Principal Investigator: Karen Eisinger, PhD
Faryabi Lab
Genome-wide signatures of replicative stress and the contributions of replication stress-induced genomic lesions to hematological malignancies
Principal Investigator: Robert Babak Faryabi, PhD
French Lab
Culture and differentiation of human induced pluripotent stem cells (iPSC) and human embryonic stem cells (hESC)
Investigator: Deborah French, PhD
Gadue Lab
Cell fate decisions, focusing on endoderm and mesoderm specification using mouse and human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells
Principal Investigator: Paul J. Gadue, PhD
Gaulton Lab
Molecular processes that regulate the infection and pathology of retroviruses, such as HIV, the impact of these infections on the immune system, and the detection of these infections using novel imaging and diagnostic approaches
Principal Investigator: Glen N. Gaulton, PhD
