PEOPLE

Jacquelyn Roth, PhD, DABMGG

Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information3400 Spruce Street
7.103 Founders Pavilion
Philadelphia, PA, 19104

Specialty Division

Precision and Computational Diagnostics

Education

BA (Major - Biology, Minor - Applied Mathematics), Franklin & Marshall College, 2004
PhD (Genetics), Thomas Jefferson University, 2011

Specialty Certification

American Board of Medical Genetics and Genomics, Clinical Cytogenetics, 2013
American Board of Medical Genetics and Genomics, Clinical Molecular Genetics, 2015

Postgraduate Training

ABMGG Fellowship, Clinical Cytogenetics, The Children's Hospital of Philadelphia, 2011-2013
ABMGG Fellowship, Clinical Molecular Genetics, The Children's Hospital of Philadelphia, 2013-2014

Awards and Honors

John Marshall Scholar, Franklin and Marshall College, 2000-2004
Howard Hughes Scholar, Franklin and Marshall College, 2001-2004
Alpha Epsilon Delta Premedical Honor Society, Franklin and Marshall College, 2003-2004
Marie D’Agostino Senior Biology Award, Franklin and Marshall College, 2004
Biology Departmental Honors, Franklin and Marshall College, 2004
M. Munson Award in Dance, Franklin and Marshall College, 2004
NIH Training Grant, Thomas Jefferson University, 2006-2009
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2008
Cis B. Golder Quality of Life Grant, Living Beyond Breast Cancer, 2011
Mouse Genetics Travel Scholarship, International Mammalian Genome Conference, 2011
Jefferson College of Graduate Studies Alumni Travel Fellowship, Thomas Jefferson University, 2011
The Fredric Rieders Renaissance Foundation Graduate Student Recognition Award, Thomas Jefferson University, 2011
Student Travel Award, American Cytogenetics Conference, 2012
Jefferson College of Graduate Studies Alumni Prize for Best Thesis, Thomas Jefferson University, 2012
Going Beyond Award, Living Beyond Breast Cancer, 2012
Spirit of the Promise Award, Susan G. Komen Philadelphia, 2012
Research Poster Day Prize, The Children’s Hospital of Philadelphia, 2014

Memberships and Professional Organizations

American Association for the Advancement of Science, 2007 - 2009
The American Society for Cell Biology, 2008 - 2009
Young Survival Coalition, 2010 - 2014
Living Beyond Breast Cancer, 2010 - 2019
Susan G. Komen for the Cure Philadelphia, 2010 - 2016
National Post-Doctoral Association, 2011 - 2014
American Cytogenetics Conference, 2012 - Present
Association for Molecular Pathology, 2014 - Present
College of American Pathologists, 2016 - Present
National Cancer Institutes Funded Grant of Drs. Kate Nathanson and Steve Joffe, 2019 - Present

Web Links


Selected Publications

Leukemias, Lymphomas, and Plasma Cell Disorders

Jennifer J.D. Morrissette, Jacquelyn J. Roth, Selina M. Luger and Edward A. Stadtmauer, Principles and Practice of Medical Genetics and Genomics: Hematologic, Renal, and Immunologic Disorders, 2023

Significance of RUNX1 mutation in BCR-ABL1 positive acute myeloid leukemia – a diagnostic dilemma in a young woman with persistent bleeding

Sharmila Ghosh, Jacquelyn Roth, Daria Babushok & Megan Lim, Leukemia and Lymphoma 63(8): 1975-197, 2022

AMP case report: A case of a rare myeloid neoplasm presenting with features mimicking primary myelofibrosis

Neha Gupta, Selina Luger, Dale M. Frank, Jacquelyn J. Roth, Salvatore F. Priore, CAP Today, 2022

TP53 Mutation and Extraneural Metastasis of Glioblastoma: Insights From an Institutional Experience and Comprehensive Literature Review

Zhang X, Katsakhyan L, LiVolsi VA, Roth JJ, Rassekh CH, Bagley SJ, Nasrallah MP, Am J Surg Pathol. 45(11): 1516-1526, 2021, PMID:34366423

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Optimization of Sources of Circulating Cell-Free DNA Variability for Downstream Molecular Analysis

Jacob E.Till, Taylor A.Black, Caren Gentile, Aseel Abdalla, Zhuoyang Wang, Hareena K.Sangha, Jacquelyn J.Roth, Robyn Sussman, Stephanie S.Yee, Mark H.O'Hara, Jeffrey C.Thompson, CharuAggarwal, Wei-Ting Hwang, Kojo S.J.Elenitoba-Johnson, Erica L.Carpenter, J. Mol. Diag. 23(11): 1545-52, 2021, PMID:34454115

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Optimization of quality control metrics for the Archer FusionPlex™ sequencing assay

S. Hurwitz, X. Zhang, S. Priore, J. Roth, J Mol Diagn 23(11): 1639, 2021

Useful Case Examples for Troubleshooting Quality Issues in a Massively Parallel Sequencing Laboratory

A. Dusenbery, V. Van Deerlin, S. Priore, J. Roth, J Mol Diagn 23(11): 1640, 2021

Clinical laboratory mutation analysis performed on aggressive B cell non-Hodgkin lymphoma patient biopsies

Landsburg, D. J., Caponetti, G. C., Bagg, A., Schuster, S. J., Nasta, S., Gerson, J. M., Frank, D. M., Barta, S. K., Svoboda, J., Bhattacharyya, S., Qualtieri, J. N., Lim, M. S., Chong, E. A., Roth, J. J., Priore, S. F., Deihimi, S., Morrissette, J. J. D., American Society of Clinical Oncology, 2021

TP53 mutation and extraneural metastasis of glioblastoma: insights from an institutional experience and comprehensive literature review

Zhang X, Katsakhyan L, LiVolsi VA, Roth JJ, Rassekh CH, Bagley SJ, Nasrallah MP, American Association of Neuropathologists, 2021

Rhabdoid tumors

Jaclyn A. Biegel and Jacquelyn J. Roth, The Hereditary Basis of Childhood Cancer, 2021