Amrom Obstfeld, MD, PhD

Assistant Professor of Clinical Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine
Assistant Director of Hematology and Coagulation Laboratories
Children's Hospital of Philadelphia

Contact InformationDepartment of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia
5th Floor Building - 5199C
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-426-7491
Fax: 215-590-1736


B.A. (Biology, Asian and Middle Eastern Studies), University of Pennsylvania, 2003.
Ph.D. (Physiology), Columbia University, 2010.
M.D., College of Physicians and Surgeons, Columbia University, 2012.

Specialty Certification

American Board of Pathology, 2015

Postgraduate Training

Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 2012-2015
Certificate - Biomedical Informatics, University of Pennsylvania, 2019-2020

Awards and Honors

Magna Cum Laude, University of Pennsylvania, 2003
MD/PhD Symposium Award, Columbia University, 2007
Immunology Retreat 2nd Place Poster Prize, Columbia University, 2008
Student Research Day MD/PhD Award, Columbia University, 2010
Doctor Harold Lee Meierhof Memorial Prize for outstanding achievement in Pathology, Columbia University, 2012
The Leonard Berwick Residency Training Award, Perelman School of Medicine at the University of Pennsylvania, 2015
Penn Institute of Biomedical Informatics Junior Faculty Travel Award, 2016
Society of '67 Open Access Publication Award, Association of Pathology Chairs, 2020

Memberships and Professional Organizations

Association for Pathology Informatics, 2015 - Present
International Society for Laboratory Hematology, 2016 - Present
College of American Pathologists, 2018 - Present
International Council for Standardization in Haematology, 2018 - Present
Harmonization Oversight Group, International Consortium for Harmonization of Clinical Laboratory Tests, 2019 - Present
Joint Committee for Traceability in Laboratory Medicine, Blood Cell Counting and Typing Team, 2020 - Present

Web Links

Selected Publications

Data Mining Approaches to Reference Interval Studies

Amrom E Obstfeld, Khushbu Patel, James C Boyd, Julia Drees, Daniel T Holmes, John P A Ioannidis, Arjun K Manrai, Clinical Chemistry 67(9): 1175-1181, 2021, PMID:34402506

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Implementation of an extraction-free COVID RT-PCR workflow in a pediatric hospital setting

Dumm RE, Elkan M, Fink J, Richard-Greenblatt M, Obstfeld AE, Harris RM., J Appl Lab Med, 2021, PMID:34165533

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Clinical impact of genomic characterization of 15 patients with acute megakaryoblastic leukemia-related malignancies

Lalonde E, Rentas S, Wertheim G, Cao K, Surrey LF, Lin F, Zhao X, Obstfeld A, Aplenc R, Luo M, Li MM, Cold Spring Harb Mol Case Study 7(2): , 2021

Facilitating Test Status Information Communication in the Time of COVID-19

Master SR, Neide B, Kollu S, Mulchandani S, Harris RM, Obstfeld AE, Acad Pathol 8(): , 2021

"Aiding clinical assessment of pediatric sepsis using hematological analyzer with machine learning techniques"

Wang R, Huang B, Obstfeld A., ISLH Virtual Meeting 2020, 2020

Utility of repeat testing in the evaluation for von Willebrand disease in pediatric patients

Doshi BS, Rogers RS, Whitworth HB, Stabnick EA, Britton J, Butler RB, Obstfeld AE, Witmer CM, Journal of Thrombosis and Haemostosis 17(1): 1838-1847, 2019, PMID:31350816

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Cell-free RNA is More Sensitive than DNA for the Detection of Pediatric Bacterial Sepsis via Shotgun Metagenomic Sequencing

Dougherty C, Fischer NL, Maramba A, Mitchell S, Obstfeld AE, Graf EH, Association for Molecular Pathology Annual Meeting, Baltimore, Maryland, 2019

Genomic Characterization Of Pediatric Acute Megakaryoblastic Leukemia and the Clinical Impact

Lalonde E, Wertheim GB, Surrey LF, Fumin L, Xiaonan Z, Obstfeld AE, Luo M, Association for Molecular Pathology Annual Meeting, 2019

Validation of a Red Blood Cell Pitting Assay for Monitoring Splenic Function.

Cheng C, Shibutani S, Paessler M, Obstfeld AE, Annual Meeting of the International Society of Laboratory Hematology 2019, 2019

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