PEOPLE

Vijay Bhoj, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania

Contact Information3400 Civic Ctr Blvd.
8-303 Smilow South Tower
Philadelphia, PA, 19104

Email: vijay.bhoj@uphs.upenn.edu

Specialty Division

Transfusion Medicine & Therapeutic Pathology

Research Expertise

My research expertise lies in the area of cellular immunotherapy. In particular, I have experience in preclinical development of immunotherapy that employ engineered immuno-receptors (e.g. chimeric antigen receptors) for the treatment of cancer and of non-malignant conditions such as autoimmunity and transplant rejection.

In addition to conducting preclinical in vitro and in vivo studies using animal models, I have experience in conducting correlative studies in patients undergoing immunotherapy to study the immune impact of such therapies.

Education

B.S. (Biology), The College of New Jersey, 2002
PhD (Immunology), University of Texas Southwestern Medical Center, 2010
MD University of Texas Southwestern Medical Center, 2010

Specialty Certification

American Board of Pathology - Clinical Pathology, 2013
American Board of Pathology - Transfusion Medicine, 2014

Postgraduate Training

Clinical Pathology, Hospital of the University of Pennsylvania, 2010-2013
Clinical Pathology Chief Resident, Hospital of the University of Pennsylvania, 2012-2013
Transfusion Medicine, Hospital of the University of Pennsylvania, 2013-2014
Postdoctoral researcher, The University of Pennsylvania, 2013-present

Awards and Honors

William Pepper Fellowship
Pathology and Laboratory Medicine
University of Pennsylvania, 2013
Distinguished Young Investigator Award
Immuno-Oncology Young Investigator's Forum, 2015
Gift of Life Award
Ree-Wynn Foundation, 2016
Research Day Poster Award
Children's Hospital of Philadelphia, 2016

Memberships and Professional Organizations

AABB, 2010 - Present
American Society for Apheresis, 2012 - Present
American Association for Cancer Research, 2016 - Present
American Society for Hematology, 2016 - present

Web Links


Selected Publications

CAR-T cells (CTL019) for Refractory B-cell Lymphomas

Schuster SJ, Svoboda J, Chong EA, Nasta SD, Mato AR, Anak O, Brogdon JL, Pruteanu-Malinici I, Bhoj V, Landsburg D, Wasik M, Levine BL, Lacey SF, Melenhorst JJ, Porter DL, June CH, New England Journal of Medicine 377(26): 2545-2554, 2017

The thrombotic microangiopathy Registry of North America: A United States multi-institutional TMA network.

Metjian Ara, Tanhehco Yvette C, Aqui Nicole, Bhoj Vijay G, Jamensky Lita, Marques Marisa B, Onwuemene Oluwatoyosi, Pham Huy P, Arepally Gowthami M, Journal of clinical apheresis 31(5): 448-53, 2016, PMID:26575088

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Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease.

Ellebrecht Christoph T, Bhoj Vijay G, Nace Arben, Choi Eun Jung, Mao Xuming, Cho Michael Jeffrey, Di Zenzo Giovanni, Lanzavecchia Antonio, Seykora John T, Cotsarelis George, Milone Michael C, Payne Aimee S, Science 353(6295): 179-84, 2016, PMID:27365313

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Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy.

Bhoj Vijay G, Arhontoulis Dimitrios, Wertheim Gerald, Capobianchi James, Callahan Colleen A, Ellebrecht Christoph T, Obstfeld Amrom E, Lacey Simon F, Melenhorst Jan J, Nazimuddin Farzana, Hwang Wei-Ting, Maude Shannon L, Wasik Mariusz A, Bagg Adam, Schuster Stephen, Feldman Michael D, Porter David L, Grupp Stephen A, June Carl H, Milone Michael C, Blood 128(3): 360-70, 2016, PMID:27166358

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Novel gene and cellular therapy approaches for treating HIV.

Bhoj Vijay G, Thibodeaux Suzanne R, Levine Bruce L, Discovery medicine 21(116): 283-92, 2016, PMID:27232514

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Lipoprotein apheresis.

Bhoj Vijay G, Sachais Bruce S, Current atherosclerosis reports 17(7): 39, 2015, PMID:26004920

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Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors.

Wang Enxiu, Wang Liang-Chuan, Tsai Ching-Yi, Bhoj Vijay, Gershenson Zack, Moon Edmund, Newick Kheng, Sun Jing, Lo Albert, Baradet Timothy, Feldman Michael D, Barrett David, Puré Ellen, Albelda Steven, Milone Michael C, Cancer immunology research 3(7): 815-26, 2015, PMID:25941351

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Pallor and lethargy in a 19-month-old boy.

Bhoj Elizabeth J, Bhoj Vijay, Henretig Fred M, Pediatric emergency care 30(6): 444-6, 2014, PMID:24892689

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Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice.

Torres Juan Pablo, Gomez Ana M, Khokhar Shama, Bhoj Vijay G, Tagliabue Claudia, Chang Michael L, Kiener Peter A, Revell Paula A, Ramilo Octavio, Mejias Asuncion, Respiratory research 11(): 125, 2010, PMID:20843364

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Ubiquitylation in innate and adaptive immunity.

Bhoj Vijay G, Chen Zhijian J, Nature 458(7237): 430-7, 2009, PMID:19325622

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