PEOPLE

Adam C. Cuker, MD, MS

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania, Assistant Professor of Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine

Contact InformationPenn Comprehensive Hemophilia and Thrombosis Program
HUP, 3 Dulles
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-8015
Fax: 215-615-6599

Specialty Division

Laboratory Medicine

Research Expertise

Heparin-induced thrombocytopenia, Immune thrombocytopenia, Thrombosis, Anticoagulation, Platelet disorders

Itmat Expertise

Hemostasis and thrombosis.

Clinical Expertise

Clotting disorders, Bleeding disorders, Platelet disorders

Education

BS (Biological Sciences), Cornell University, 1998
MD (Medicine), Yale University, 2003
MS (Translational Research), University of Pennsylvania, 2010

Specialty Certification

American Board of Internal Medicine, 2006
American Board of Internal Medicine, Hematology, 2009

Postgraduate Training

Intern in Internal Medicine, Brigham and Women's Hospital, 2003-2004
Resident in Internal Medicine, Brigham and Women's Hospital, 2004-2006
Fellow in Hematology/Oncology, University of Pennsylvania, 2006-2009
Leading Success Leadership Training, University of Pennsylvania, 2015-2016

Awards and Honors

Medical Student Research Training Fellowship, National Institutes of Health, 1999-1999
Farr Scholarship, Yale University, 2000
Medical Student Research Training Fellowship, Howard Hughes Medical Institute, 2000-2001
Medical Student Research Continued Support Fellowship, Howard Hughes Medical Institute, 2001-2003
Jane Alavi Outstanding Fellow in Hematology/Oncology, University of Pennsylvania, 2007
Clinical Loan Repayment Award, National Institutes of Health, 2008-2010
Haemophilia Academy Award, Haemophilia Academy, 2008
Clinical Research Training Institute, American Society of Hematology, 2008-2009
Outstanding Peer Reviewer Award, Pharmacoepidemiology and Drug Safety, 2009
Austrian Award, Department of Medicine, 2010
Eberhard Mammen Young Investigator Award, Seminars in Thrombosis and Hemostasis, 2011
Outstanding peer reviewer, Annals of Internal Medicine, 2011
Outstanding peer reviewer, Annals of Internal Medicine, 2012
Gift of Life Award, Ree Wynn Foundation, 2013
Cuker A et al., Blood 2012;120:4160 featured as one of 4 hematology articles in Update in Hematology and Oncology: Evidence Published in 2012, Annals of Internal Medicine, 2013
Outstanding peer reviewer, Annals of Internal Medicine, 2013
Outstanding peer reviewer, Annals of Internal Medicine, 2014
The John Glick, MD Prize for Teaching Excellence in Oncology, University of Pennsylvania, 2015
Faculty, American Society of Hematology Clinical Research Training Institute, 2015

Memberships and Professional Organizations

American Society of Hematology, 2006 - Present
National Hemophilia Foundation, 2007 - Present
International Society on Thrombosis and Haemostasis, 2008 - Present
Hemostasis and Thrombosis Research Society, 2008 - Present
American College of Physicians, 2009 - Present
American Society of Hematology Clinical Research Training Institute, 2011 - Present
Anticoagulation Forum, 2011 - Present
Data Safety and Monitoring Committee, Bridging ITP Study, 2013 - Present
Hemostasis and Thrombosis Research Society Mentored Research Award Program, 2014 - 2014
American Thrombosis and Hemostasis Network, 2015 - Present
American College of Cardiology, 2015 - Present

Web Links


Selected Publications

Novel diagnostic assays for heparin-induced thrombocytopenia

Cuker A, Rux AH, Hinds JL, Dela Cruz M, Yarovoi SV, Brown IAM, Yang W, Konkle BA, Arepally GM, Watson SP, Cines DB, Sachais BS, Blood 121(): 3727-3732, 2013

Protamine-induced thrombocytopenia?

Cuker A, Cines DB, Blood 121(): 2818-2819, 2013

Reversal of novel oral anticoagulants in patients with major bleeding

Siegal D, Cuker A, J Thromb Thrombolysis 35(): 391-398, 2013

Similarity in Joint Function Limitation in Type 3 Von Willebrand Disease and Moderate Haemophilia A

Sood S, Cuker A, Wang C, Metjian A, Chiang E, Soucie J, Konkle B, Haemophilia 19(4): 595-601, 2013, PMID:23534856

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Investigation of a potential protective mechanism against heparin-induced thrombocytopenia in patients on chronic intermittent hemodialysis

Tanhehco YC, Cuker A, Rudnick M, Sachais BS, Thromb Res 131(): 244-248, 2013

Predictive value of the 4Ts scoring system for heparin-induced thromboctopenia: a systematic review and meta-analysis

Cuker A, Gimotty PA, Crowther MA, Warkentin TE, Blood 120(): 4160-4167, 2012, PMID:22990018

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Dynamic antibody binding properties in the pathogenesis of HIT

Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB, Blood 120(): 1137-1142, 2012, PMID:22577175

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Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism

Martinez M, Cuker A, Mills A, Lightfoot R, Fan Y, Tang W, Hazen SL, Ischiropoulos H, Free Radic Biol Med 53(): 230-236, 2012, PMID:22580301

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How I treat heparin-induced thrombocytopenia

Cuker A, Cines DB, Blood 119(): 2209-2218, 2012, PMID:22246036

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Comtemporary management of primary immune thrombocytopenia (ITP) in adults

Lakshmanan S, Cuker A, J Thromb Haemost 10(): 1988-1998, 2012, PMID:22863415

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