Matthew B. Palmer, MD, PhD
Associate Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Director, Renal Pathology Service
Hospital of the University of Pennsylvania
Contact InformationHospital of the University of Pennsylvania
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Email: matthew.palmer@pennmedicine.upenn.edu
Specialty Division
Anatomic Pathology
Education
BS (Zoology and Russian), Brigham Young University, 1998
MD (Doctor of Medicine), Emory University School of Medicine, 2008
PhD (Biochemistry, Cell, and Developmental Biology), Emory University, 2008
Specialty Certification
American Board of Pathology, Anatomic and Clinical Pathology, 2012
Postgraduate Training
Resident, Anatomic and Clinical Pathology, Yale-New Haven Hospital/Yale School of Medicine, 2008-2012
Fellow in Renal and Genitourinary Pathology, Department of Pathology, Yale School of Medicine, New Haven, CT, 2012-2013
Awards and Honors
University Scholarship, Brigham Young University, 1992
DOE Undergraduate Research Fellowship, UC Davis, 1996
Dean's List, College of Biology and Agriculture, Brigham Young University, 1996
NSF Research Training Program, National Museum of Natural History, 1998
NIH Medical Scientist Training Program Fellowship, Emory University, 1999-2008
NIH Cell and Molecular Biology Training Grant, Emory University, 2005
Woodruff Scholarship, Emory University School of Medicine, 2007-2008
Memberships and Professional Organizations
Renal Pathology Society, 2012-present
United States and Canadian Academy of Pathology, 2012-2014
College of American Pathologists, 2012-2014
Nephrotic Syndrome Study Network (NEPTUNE), 2013-present
American Society of Nephrology, 2015-present
Cure Glomerulonephropathy Network (CureGN), 2016-present
Transformative Research in Diabetic Nephropathy (TRIDENT), 2016-present
Web Links
Selected Publications
The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene.
Dhanunjay Mukhi, Lakshmi Prasanna Kolligundla, Tomohito Doke, Magaiver Andrade- Silva, Hongbo Liu, Matthew Palmer, Katalin Susztak, Cell Reports 44(4): , 2025, PMID:40138314
Zebra Bodies in Kidney Biopsy: Drug-Induced Phospholipidosis in a Patient With Systemic Lupus Erythematosus.
Aguila T, Madan R, Palmer MB, Derk CT, Journal of Rheumatology, 2025, PMID:40041993
Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N, Chen HC, Tao R, Tarng DC, Hsieh FJ, Chen SA, Yang SF, Lee MY, Kwok PY, Wu JY, Chen CH, Khan A, Limdi NA, Wei WQ, Walunas TL, Karlson EW, Kenny EE, Luo Y, Kottyan L, Connolly JJ, Jarvik GP, Weng C, Shang N, Cole JB, Mercader JM, Mandla R, Majarian TD, Florez JC, Haas ME, Lotta LA; Regeneron Genetics Center‡; GHS-RGC DiscovEHR Collaboration§; Drivas TG; Penn Medicine BioBank¶; Vy HMT, Nadkarni GN, Wiley LK, Wilson MP, Gignoux CR, Rasheed H, Thomas LF, Åsvold BO, Brumpton BM, Hallan SI, Hveem K, Zheng J, Hellwege JN, Zawistowski M, Zöllner S, Franceschini N, Hu H, Zhou J, Kiryluk K, Ritchie MD, Palmer M, Edwards TL, Voight BF, Hung AM, Susztak K, Science 387(6734): 4753, 2025, PMID:39913582
Improved therapeutic efficacy of a bifunctional anti-C5 mAb-FH SCR1-5 fusion protein over anti-C5 mAb in an accelerated mouse model of C3 glomerulopathy.
Sato S, Miwa T, Gullipalli D, Golla M, Mohammadyari E, Zhou L, Palmer M, Song WC., Immunohorizons 9(3): , 2025, PMID:39865974
Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression.
Abedini A, Levinsohn J, Klötzer KA, Dumoulin B, Ma Z, Frederick J, Dhillon P, Balzer MS, Shrestha R, Liu H, Vitale S, Bergeson AM, Devalaraja-Narashimha K, Grandi P, Bhattacharyya T, Hu E, Pullen SS, Boustany-Kari CM, Guarnieri P, Karihaloo A, Traum D, Yan H, Coleman K, Palmer M, Sarov-Blat L, Morton L, Hunter CA, Kaestner KH, Li M, Susztak K., Nature Genetics 56(8): 1712-1724, 2024, PMID:39048792
Perioperative nivolumab versus observation in patients with renal cell carcinoma undergoing nephrectomy (PROSPER ECOG-ACRIN EA8143): an open-label, randomised, phase 3 study.
Allaf ME, Kim SE, Master V, McDermott DF, Harshman LC, Cole SM, Drake CG, Signoretti S, Akgul M, Baniak N, Li-Ning E, Palmer MB, Emamekhoo H, Adra N, Kaimakliotis H, Ged Y, Pierorazio PM, Abel EJ, Bilen MA, Ogan K, Moon HH, Ramaswamy KA, Singer EA, Mayer TM, Lohrey J, Margulis V, Gills J, Delacroix SE, Waples MJ, James AC, Wang P, Choueiri T, Michaelson MD, Kapoor A, Heng DY, Shuch B, Leibovich BC, Lara PN, Manola J, Maskens D, Battle D, Uzzo R, Bratslavsky G, Haas NB, Carducci MA., Lancet Oncology 25(8): 1038-1052, 2024, PMID:38942046
Unraveling the epigenetic code: human kidney DNA methylation and chromatin dynamics in renal disease development.
Yan Y, Liu H, Abedini A, Sheng X, Palmer M, Li H, Susztak K., Nature Communications 15(1): 873, 2024, PMID:38287030
Clinicopathologic Features of Antibrush Border Antibody Disease.
Murphy JD, Caza TN, Cassol CA, Storey A, Ambruzs JM, Boils C, Walker PD, Sharma S, Messias N, Hennigar R, Andeen NK, VanBeek C, Palmer M, Sankar L, Sanghi P, Dinesh K, Dicker L, Urisman A, Larsen CP., Kidney International Reports 9(2): 370-382, 2023, PMID:38344713
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria, Reproducibility, and Clinicopathologic Correlations
Matthew B Palmer; Virginie Royal; J. Charles Jennette; Abigail R. Smith; Qian Liu; Josephine M. Ambruzs; Nicole K. Andeen; Vivette D. D’Agati; Agnes B. Fogo; Joseph Gaut; Rasheed A. Gbadegesin; Larry A. Greenbaum; Jean Hou; Margaret E Helmuth; Richard A. Lafayette; Helen Liapis; Bruce Robinson; Michael B. Stokes; Katherine Twombley; Hong Yin; Cynthia C. Nast; for the CureGN Consortium, Glomerular Diseases 3(1): 248-257, 2023
Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration.
Nova-Camacho LM, Acosta AM, Trpkov K, Sangoi AR, Pierre A, Chou A, Yilmaz A, Morini A, Rodrigues Â, Fletcher CDM, Perez-Montiel D, Maclean F, Contreras F, Queipo FJ, Muñiz Unamunzaga G, Mesa H, de Torres I, Ruiz I, Alvarado-Cabrero I, Lobo J, Schwartz L, Cheng L, Akgul M, García-Martos M, Palmer MB, Aron M, Raspollini MR, Manrique Celada M, Hwang M, Idrees MT, Rioux-Leclercq N, Zalles N, Vergara N, Lal P, Wobker S, Kammerer-Jacquet SF, Prendeville S, Tilmant T, Ulbright TM, Verkarre V, Collins K, Williamson SR, Panizo A., Human Pathology 139(): 37-46, 2023, PMID:37331529
