Minjie Luo, PhD
Associate Professor of Clinical Pathology and Laboratory MedicinePerelman School of Medicine at the University of Pennsylvania
Contact InformationThe Children’s Hospital of Philadelphia
716D Abramson Research Building
34th and Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-5101
Fax: 215-590-2156
Education
PhD Zhejiang University School of Medicine, Hangzhou, China, 2000
Specialty Certification
Diplomate, American Board of Medical Genetics and Genomics, Clinical Molecular Genetics, 2011
Diplomate, American Board of Medical Genetics and Genomics, Clinical Cytogenetics, 2013
Postgraduate Training
Research Fellow, Cancer Institute of New Jersey/Department of Genetics, University of Medicine and Dentistry of New Jersey, 2001-2003
American Board of Medical Genetics & Genomics Fellow in Clinical Molecular Genetics, Mount Sinai School of Medicine, New York, 2008-2010
American Board of Medical Genetics & Genomics Fellow in Clinical Cytogenetics, Mount Sinai School of Medicine, New York, 2010-2012
Awards and Honors
Scientific & Technical Development Award of Zhejiang Province (3rd Place), Government of Zhejiang Province, 1997
GuangHua Scholarship, Zhejiang University, 1998
GuangHua Scholarship, Zhejiang University, 1999
Certificate of Honor, Health Department of Zhejiang Province, 1999
Scientific & Technical Development Award of Zhejiang Province (3rd Place), Government of Zhejiang Province, 1999
Outstanding Graduate Student for Doctor and Master's Degree Recipients of Zhejiang Province, 2000
Gallo Award for Outstanding Cancer Research, Cancer Research in New Jersey, 2002
Research Achievement Award, The Research Committee in UMDNJ-RWJMS, New Jersey, 2003
Scientific & Technical Development Award of Zhejiang Province (1st Place), Government of Zhejiang Province, 2005
Top Rated Poster, The American Society of Human Genetics Annual Meeting, 2016
Memberships and Professional Organizations
American Society of Human Genetics, 2003 - Present
American College of Medical Genetics, 2012 - Present
College of American Pathologists, 2015 - Present
Children's Oncology Group, 2015 - Present
Cancer Genomics Consortium, 2015 - Present
Association for Molecular Pathology, 2024 - Present
Web Links
Selected Publications
Identification of TP53 germline variants in pediatric patients undergoing tumor testing: strategy and prevalence
Luo Minjie, Wong Derek, Zelley Kristin, Wu Jinhua, Schubert Jeffery, Denenberg Elizabeth H, Fanning Elizabeth A, Chen Jiani, Gallo Daniel, Golenberg Netta, Patel Maha, Conlin Laura K, Maxwell Kara N, Wertheim Gerald B, Surrey Lea F, Zhong Yiming, Brodeur Garrett M, MacFarland Suzanne P, Li Marilyn M, J Natl Cancer Inst 116(8): 1356-1365, 2024, PMID:38702830
Uncovering the genetic etiology of inherited bone marrow failure syndromes using a custom-designed next-generation sequencing panel
Lin Fumin, Cao Kajia, Chang Fengqi, Oved Joseph H, Luo Minjie, Fan Zhiqian, Schubert Jeffrey, Wu Jinhua, Zhong Yiming, Gallo Daniel J, Denenberg Elizabeth H, Chen Jiani, Fanning Elizabeth A, Lambert Michele P, Paessler Michele E, Surrey Lea F, Zelley Kristin, MacFarland Suzanne, Kurre Peter, Olson Timothy S, Li Marilyn M, J Mol Diagn 26(3): 191-201, 2024, PMID:38103590
Genomic profiling of pediatric hematologic malignancies and diagnosis of cancer predisposition syndromes: tumor-only versus paired tumor-normal sequencing
Newman Haley, Clark Mary Egan, Wong Derek, Wu Jinhua, Brodeur Garrett M, Hunger Stephen P, Tasian Sarah K, Olson Timothy, Warren Julia T, Teachey David T, Bona Kira, Schubert Jeffrey, Golenberg Netta, Patel Maha, Denenberg Elizabeth H, Fanning Elizabeth A, Chen Jiani, Luke Tamara, Charles Sarah, Gallo Daniel, Cao Kajia, Fu Weixuan, Fan Zhiqian, Surrey Lea F, Wertheim Gerald, Luo Minjie, MacFarland Suzanne P, Li Marilyn M, Zhong Yiming, Haematologica 109(9): 3024-3030, 2024, PMID:38385299
Comprehensive gene panel testing for hearing loss in children: understanding factors influencing diagnostic yield
Yamamoto Nobuko, Balciuniene Jorune, Hartman Tiffiney, Diaz-Miranda Maria Alejandra, Bedoukian Emma, Devkota Batsal, Lawrence Audrey, Golenberg Netta, Patel Maha, Tare Archana, Chen Robert, Schindler Emma, Choi Jiwon, Kaur Maninder, Charles Sarah, Chen Jiani, Fanning Elizabeth A, Dechene Elizabeth, Cao Kajia, Jill Murrell R, Rajagopalan Ramakrishnan, Bayram Yavuz, Dulik Matthew C, Germiller John, Conlin Laura K, Krantz Ian D, Luo Minjie, J Pediatr 262(): 113620, 2023, PMID:37473993
Long-read sequencing for molecular diagnostics in constitutional genetic disorders
Conlin Laura K, Aref-Eshghi Erfan, McEldrew Deborah A, Luo Minjie, Rajagopalan Ramakrishnan, Hum Mutat 43(11): 1531-1544, 2022, PMID:36086952
Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma
Xu Feng, Viaene Angela N, Ruiz Jenny, Schubert Jeffrey, Wu Jinhua, Chen Jiani, Cao Kajia, Fu Weixuan, Bagatell Rochelle, Fan Zhiqian, Long Ariel, Pagliaroli Luca, Zhong Yiming, Luo Minjie, Kreiger Portia A, Surrey Lea F, Wertheim Gerald B, Cole Kristina A, Li Marilyn M, Santi Mariarita, Storm Phillip B, Acta Neuropathol Commun 10(1): 102, 2022, PMID:35836290
Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss
Chen Robert, Diaz-Miranda Maria Alejandra, Aref-Eshghi Erfan, Hartman Tiffiney R, Griffith Christopher, Morrison Jennifer L, Wheeler Patricia G, Torti Erin, Richard Gabriele, Kenna Margaret, Dechene Elizabeth T, Spinner Nancy B, Bai Renkui, Conlin Laura K, Krantz Ian D, Amr Sami S, Luo Minjie, Hum Mutat 43(12): , 2022, PMID:35870179
Congenital tumors of the central nervous system: an institutional review of 64 cases with emphasis on tumors with unique histologic and molecular characteristics
Viaene Angela N., Pu Cunfeng, Perry Arie, Li Marilyn M., Luo Minjie, Santi Mariarita, Brain Pathol 31(1): , 2021, PMID:32681571
NTRK fusions identified in pediatric tumors: the frequency, fusion partners, and clinical outcome
Zhao Xiaonan, Kotch Chelsea, Fox Elizabeth, Surrey Lea F., Wertheim Gerald B., Baloch Zubair W., Lin Fumin, Pillai Vinodh, Luo Minjie, Kreiger Portia A., Pogoriler Jennifer, Linn Rebecca L, Russo Pierre A., Santi Mariarita, Resnick Adam C., Storm Phillip B., Hunger Stephen P., Bauer Andrew J., Li Marilyn, JCO Precis Oncol 5(): 204-214, 2021, PMID:34036219
Pediatric somatic tumor sequencing identifies underlying cancer predisposition
MacFarland Suzanne P., Zelley Kristin, Surrey Lea F., Gallo Daniel, Luo Minjie, Raman Pichai, Wertheim Gerald, Hunger Stephen P., Li Marilyn, and Brodeur Garrett M, JCO Precis Oncol 3(): PO.19.00062, 2019, PMID:32783018
