Ping Wang, PhD, DABCC, FAACC
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Director of the Clinical Chemistry Section and Core Laboratory
University of Pennsylvania Perelman School of Medicine
Contact InformationHospital of University of Pennsylvania
University of Pennsylvania
3400 Spruce St.
Founders 7.103
Philadelphia, PA 19104
Office: 215-614-6062
Lab: 215-400-1526 (cell)
Email: Ping.Wang2@pennmedicine.upenn.edu
Specialty Division
Laboratory Medicine
Itmat Expertise
Next-generation technologies that advance precision diagnosis and prognosis using bioengineering, nanotechnology, chemistry and microfluidics; clinical method development and clinical trials
Clinical Expertise
Dr. Wang's clinical expertise includes general Clinical Chemistry, Automation, Point-of-care Testing, Toxicology and Clinical Mass Spectrometry and Molecular Diagnostics.
Other Expertise
Dr. Wang has also worked with industry partners to translate diagnostic tools in development into clinical applications, by way of pre-submission clinical studies and clinical trials.
Research Expertise
Dr. Wang's research interests include improving analytic methods for precision disease diagnosis and prognosis by developing next-generation point of care devices with novel sensors, materials and microfluidics.
Education
BS (Biological Sciences & Biotechnology), Tsinghua University, China, 2000
PhD (Molecular & Cellular Pharmacology), University of Wisconsin-Madison, 2005
Specialty Certification
American Board of Clinical Chemistry, Molecular Diagnostics subspecialty #47, 2008
American Board of Clinical Chemistry, Clinical Chemistry subspecialty #1032, 2008
American Board of Clinical Chemistry, Toxicological Chemistry subspecialty #127, 2011
Postgraduate Training
Clinical Chemistry Fellowship, COMACC-accredited, University of California, San Francisco, 2005-2007
Awards and Honors
Novo Nordisk Scholarship in Life Sciences, 1998
American Heart Association Predoctoral Fellowship, 2002-2004
University of Wisconsin-Madison Vilas Travel Award, 2004
American Association of Clinical Chemistry Annual Meeting, Student Poster Contest Award, Honorable Mention, 2006
Paul E Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists, 2006
American Association of Clinical Chemistry Annual Meeting, Student Research Travel Grant, 2007
National Academy of Clinical Biochemistry Distinguished Abstract Award, 2009
Finalist, Outstanding Research Award in Molecular Pathology/Pharmacogenomics, AACC Molecular Pathology Division, 2009
National Academy of Clinical Biochemistry Distinguished Abstract Award, 2012
Finalist, Outstanding Research Award in Molecular Pathology/Pharmacogenomics, AACC Molecular Pathology Division, 2012
Career Cornerstone Award, 2013
Pathology Leadership Academy, Association of Pathology Chairs, 2016
Memberships and Professional Organizations
American Association of Clinical Chemistry, 2005 - Present
Northern California Section, American Association of Clinical Chemistry, 2006 - 2006
Academy of Clinical Laboratory Physicians and Scientists, 2006 - Present
National Academy of Clinical Biochemistry, 2008 - Present
American Association of Clinical Chemistry, Therapeutic Drug Monitoring and Toxicology Division, 2010 - 2012
North American Chinese Clinical Chemists Association, 2010 - 2012
Association of Molecular Pathology, 2011 - Present
Immunosuppressant Scientific Committee, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, 2013 - Present
American Board of Clinical Chemistry, 2014 - 2016
Electronic Testing Task Force, American Board of Clinical Chemistry, 2014 - 2016
American Association of Clinical Chemistry, Lipoproteins and Vascular Diseases, 2014 - 2015
North American Chinese Clinical Chemists Association, 2015 - 2017
Unitegen, 2015 - 2016
Commission on Accreditation of Clinical Chemistry, 2016 - 2016
Personalized Medicine Division, American Association of Clinical Chemistry, 2017 - 2018
Roche Diagnostics US Infectious Disease Scientific Advisory Board, 2017 - 2017
American Board of Clinical Chemistry, 2017 - 2018
Association of American Medical Colleges Mid-Career Women Faculty Leadership Development Seminar, 2017 - 2017
Dr. Edward S. Cooper Leadership Training Program, Perelman School of Medicine and Wharton School of University of Pennsylvania, 2017 - 2017
FOCUS Mid-career Series/University of Pennsylvania, 2017 - 2017
NIH Center for Scientific Review, Surgical Sciences, Biomedical Imaging and Bioengineering, ZRG1 SBIB-Q 57, Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01), 2017 - present
Genome BC Canada, 2017 - 2017
Science and Practice Core Committee, American Association of Clinical Chemistry, 2019 - 2020
Committee for Omics Translation, Emerging Technologies Division, International Federation of Clinical Chemistry and Laboratory Medicine, 2019 - Present
NIH Bioengineering Sciences and Technologies IRG (BST) Center for Scientific Review Instrumentation and Systems Development (ISD) Study Section, 2019 - Present
Personalized Medicine Division, American Association of Clinical Chemistry, 2019 - 2020
American Association of Clinical Chemistry Research Prize Competition Organizing Taskforce, 2019 - Present
NIH Center for Scientific Review Special Emphasis Panel Interdisciplinary Molecular Science and Training (ZRG1 IMST-J) Small Business: Biological Chemistry, Biophysics, and Assay Development, 2020 - Present
NIH Center for Scientific Review Panel for Emergency Awards: Rapid Investigation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Coronavirus Disease 2019 (COVID-19), 2020 - Present
Societal Responses to and Preparedness for Emerging Viral Infections – 2020, The Novo Nordisk Foundation (NNF), Denmark, 2020 - Present
American Chemical Society-Division of Biochemicl Technology/European Society of Biochemical Engineering SCiences COVID19 Working Group, 2020 - Present
NIH Center for Scientific Review, Bioengineering Sciences and Technologies IRG, Instrumentation and Systems Development Study Section (ISD), 2021 - Present
FDA Medical Devices Advisory Committee, Clinical Chemistry and Clinical Toxicology Devices Panel, 2021 - Present
Web Links
Wang Lab website
360Dx Report on the Microbubbling Technology
My Diagnostics World News Interview
360Dx Report on the Fentanyl Lateral Flow Assay
Penn Medicine Q&A on the microbubbling SARS-CoV-2 antigen test
Penn Coronavirus Symposium presentation
New COVID-19 Testing Technology at Penn
Selected Publications
Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking
Chen H, Li Z, Feng S, Richard-Greenblatt M, Hutson E, Andrianus S, Glaser LJ, Rodino KG, Qian J, Jayaraman D, Collman RG, Glascock A, Bushman FD, Lee JS, Cherry S, Fausto A, Weiss SR, Koo H, Corby PM, O’Doherty U, Garfall AL, Vogl DT, Stadtmauer EA, Wang P, Clin Chem, 2021
Quantitation of Femtomolar Protein Biomarkers Using a Simple Microbubbling Digital Assay via Bright-field Smartphone Imaging
Chen H., Li Z., Zhang L., Sawaya P., Shi J., Wang P., Angewandte Chemie International Edition 58(39): 2-9, 2019
Development and Clinical Validation of a Sensitive Lateral Flow Assay for Rapid Urine Fentanyl Screening in the Emergency Department
Li Z., Chen H., Feng S., Liu K. and Wang P., Clinical Chemistry 66(2): 324-32, 2020
Current and Emerging Trends in Point-of-care Technology and Strategies for Clinical Validation and Implementation
Wang P* and Kricka LJ, Clinical Chemistry 64(10): 1439-52, 2018, PMID:29884677
A Biomarker for Concussion: The Good, the Bad and the Unknown
Reece JT, Milone MC, Wang P, Herman D and Shaw LM, The Journal of Applied Laboratory Medicine 5(1): 170-82, 2020
Point-of-care Testing for Infectious Diseases
Chen H., Liu K., Li Z. and Wang P., Clinica Chimica Acta 493(): 138-147, 2019
Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation
Xu X, Gao D, Wang P, Chen J, Ruan J, Xu J, and Xia X, Nature Scientific Reports 8(1): 11649, 2018
A Ultra-low Cost Smartphone Octochannel Spectrometer for Mobile Health Diagnostics
Wang L, Naudé N, Chang Y, Crivaro A, Kamoun M, Wang P*, and Li L*, Journal of Biophotonics 11(8): doi:10.1002/jbio.201700382, 2018, PMID:29603674
Analytical Validation of an Ultra Low-cost Mobile Phone Microplate Reader for Infectious Disease Testing
Wang L, Naudé N, Demissie M, Crivaro A, Kamoun M, Wang P*, Li L*, Clinica Chimica Acta 482(): 21-26, 2018, PMID:29580858
Falsely Increased Plasma Lactate Dehydrogenase without Hemolysis following Transport through Pneumatic Tube System
Herman D., Cobani E., Baraban E., Bagg A., and Wang P., Journal of Applied Laboratory Medicine 4(3): 433-438, 2019
Lateral Flow Assay Ruler for Quantitative and Rapid Point-of-care Testing
Li Z., Chen H. and Wang P., Analyst 144(10): 3314-22, 2019
Integrated microfluidic chip for efficient isolation and deformability analysis of circulating tumor cells
Liu Z, Chen R; Li Y; Liu J; Wang P*; Xia X* and Qin L*, Advanced Biosystems 2(10): https://doi.org/10.1002/adbi.201800200, 2018
Quality Control Practices for Chemistry and Immunochemistry in a Cohort of 21 Large Academic Medical Centers
Rosenbaum MW, Flood JG, Melanson SEF, Baumann NA, Marzinke MA, Rai AJ, Hayden J, Wu A, Ladror M, Lifshitz MS, Palmer SM, Bowen R, Babic N, Sobhani K, Giacherio D, Bocsi G, Herman DS, Wang P, Toffaletti J, Handel E, Kelly KA, Albeiroti S, Wang S, Zimmer M, Driver B, Yi X, Wilburn C, Lewandowski KB, American Journal of Clinical Pathology 150(2): 1-9, 2018
Wearable Knitted Bands For Sweat Glucose Sensing and Quantitation in Telemedicine
Wang P, Panatdasirisuk W, Zhang M, Stoltzfus A, Dion G, Yang S, 27th Critical and Point of Care Testing International Symposium, Anaheim, CA, 2018
The Prevalence and Role of Hemoglobin Variants in Biometric Screening of a Multiethnic Population: One Large Health System’s experience
Wilburn C.R., Bernard D.W., Zieske A.W, Andrieni J., Miller T. and Wang P., American Journal of Clinical Pathology 147(6): 589-95, 2017, PMID:28575177
Integrative volumetric bar-chart chip for rapid and quantitative point-of-care detection of myocardial infarction biomarker
Song Y., Wang Y., Qi W., Li Y., Xuan J., Wang P*., Qin L*, Lab on a Chip 16(15): 2955-62, 2016
Fast, Sensitive and Quantitative Point-of-care Platform for the Assessment of Drugs of Abuse in Urine, Serum and Whole Blood
Li Y, Uddayasankar U, He B, Wang P* and Qin L*, Analytical Chemistry 89(16): 8273-8281, 2017, PMID:28700829
Nanoporous Glass Integrated in Volumetric Bar-chart Chip for Point-of-care Diagnostics of Non-small Cell Lung Cancer
Li Y, Xuan J, Song Y, Qi W, Wang P*, Qin L*, ACS Nano 10(1): 1640-47, 2016
A Microfluidic Platform with Digital Readout and Ultra-Low Detection Limit for Quantitative Point-of-Care Diagnostics
Li Y, Xuan J, Song Y, Li Y, Wang P*, Qin L*, Lab on a Chip 15(16): 3300-06, 2015
High Throughput, Label-free Isolation of Cancer Stem Cells on the Basis of Cell Adhesion Capacity
Zhang Y, Wu M, Han X, Wang P*, and Qin L*, Angewandte Chemie International Edition 127(37): 1-6, 2015
