Weiner Lab Publishes in Cancer Research
January 29, 2014
The lab of David Weiner, PhD, professor of Pathology and Laboratory Medicine, and colleagues report in Cancer Research this week that the protein IL-33 boosts the immune system of a human papilloma virus animal model of cancer. IL-33 is a cytokine, a small protein that signals immune cells such as T cells to travel to a site of infection or injury. The results of the study "Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity" support the development of IL-33 isoforms as adjuvants in vaccinations against pathogens, including in the context of antitumor immunotherapy.
Read the Department of communications news release.