Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ. Nat Med. 2018 May;24(5):563-571. doi: 10.1038/s41591-018-0010-1.
Summary
This paper was one of the three papers by Penn researchers to be included in the Ten 2019 Clinical Research Achievement Awards from the Clinical Research Forum, which recognizes the ten most outstanding clinical research accomplishments in the United States during the preceding twelve months. Read the Penn Medicine press release.
