Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms
Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA Jr, Haczku A, Kambayashi T. Sci Signal. 2019 Sep 3;12(597). pii: eaax3332. doi: 10.1126/scisignal.aax3332.
Summary
The Kambayashi lab discovers that DGK-zeta activity in different cell types promotes both allergic inflammation and airway hyperresponsiveness.
