DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function

Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY. Cell Rep. 2015 Apr 21. pii: S2211-1247(15)00360-5. doi: 10.1016/j.celrep.2015.03.069.


A new study in Cell Reports by researchers from the University of Pennsylvania identifies a molecular link between DNA damage, cellular senescence and premature aging. Dr. F. Brad Johnson, is one of the co-authors of the study.
Read the Penn Department of Communications news release.