High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning

Reshef R, Huffman AP, Gao A, Luskin MR, Frey NV, Gill SI, Hexner EO, Kambayashi T, Loren AW, Luger SM, Mangan JK, Nasta SD, Richman PL, Sell M, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL. J Clin Oncol 2015 Jun 8. [Epub ahead of print] doi: 10.1200/JCO.2014.60.1203


A new study in the Journal of Clinical Oncology suggests that using a simple blood test to measure the T lymphocyte count in donors for stem cell transplants may help identify the best match for patients in need of an allogeneic stem-cell transplant and may optimize donor selection for older patients with hematologic malignancies.
Read the Department of Communications news release.