TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer
Fayngerts SA, Wu J, Oxley CL, Liu X, Vourekas A, Cathopoulis T, Wang Z, Cui J, Liu S, Sun H, Lemmon MA, Zhang L, Shi Y, Chen YH. TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer. Cancer Cell. 2014 September 18 [Epub ahead of print]. | doi: 10.1016/j.ccr.2014.07.025
Summary
More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how the phospholipid signals are controlled during tumorigenesis is not fully understood. The Chen Lab now reports that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways. The study "TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer" was published in Cancer Cell.
Read the Department of Communications news release.
