
Rebecca Lee Linn, MD
Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
University of Pennsylvania Perelman School of Medicine
Contact InformationDepartment of Pathology and Laboratory Medicine
The Children's Hospital of Philadelphia
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-1728
Fax: 215-590-1736
Email: linnr@chop.edu
Itmat Expertise
Placental Pathology
Perinatal Pathology
Clinical Expertise
Placental pathology
Perinatal pathology
Research Expertise
Placental pathology
Perinatal pathology
Education
BS (Biological Chemistry, Cum Laude), Tulane University, New Orleans, Louisiana, 2007
MD St. Louis University School of Medicine, St. Louis, Missouri, 2012
Specialty Certification
American Board of Pathology (Anatomic and Clinical Pathology), 2016
American Board of Pathology (Pediatric Pathology), 2017
Postgraduate Training
Resident in Anatomic and Clinical Pathology, Northwestern University Feinberg School of Medicine, 2012-2016
Fellow in Pediatric Pathology, The Children's Hospital of Philadelphia, 2016-2017
Awards and Honors
Henry M. Pinkerton Award for Academic Excellence in Pathology, Saint Louis University School of Medicine, 2012
Resident Recruitment Award from Society for Pediatric Pathology, Fall Meeting, Salt Lake City, Utah, 2013
Neuropathology Holiday Challenge Award, Northwestern University Feinberg School of Medicine, Department of Pathology, 2013
Autopsy Award for Outstanding Performance by a First Year Resident, Northwestern University Feinberg School of Medicine, Department of Pathology, 2013
First place for Outstanding Clinical Research Addressing Women's Health at Tenth Annual Lewis Leadership Research Day, Northwestern University Feinberg School of Medicine, 2014
Perinatal Pathology Award from Society for Pediatric Pathology, Fall Meeting, Birmingham, UK, 2014
Chief Resident, Department of Pathology, Northwestern University Feinberg School of Medicine, 2014-2015
Kent Nowels Memorial Award for Outstanding Leadership, Collegiality, and Academic Excellence, Northwestern University Feinberg School of Medicine Department of Pathology, 2016
Memberships and Professional Organizations
American Society of Clinical Pathologists, 2012 - Present
United States and Canadian Academy of Pathology, 2012 - Present
College of American Pathologists, 2012 - Present
Society of Pediatric Pathology, 2015 - Present
Web Links
Selected Publications
Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19
Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA, Journal of Extracellular Vesicles 14(4): e70051, 2025, PMID:40205960
Whole Exome Sequencing in a Population of Fetuses With Structural Anomalies
Burrill N, Schindewolf E, Pilchman L, Wright R, Crane H, Gebb J, Khalek N, Soni S, Paidas Teefey C, Oliver ER, Linn R, Moldenhauer JS., Prenat Diagn 45(3): 310-317, 2025, PMID:39743338
The human and non-human primate developmental GTEx projects.
Coorens THH, Guillaumet-Adkins A, Kovner R, Linn RL, Roberts VHJ, Sule A, Van Hoose PM; dGTEx Consortium., Nature 637(8046): 557-564, 2025, PMID:39815096
Congenital Heart Disease Fetuses Have Decreased Mid-Gestational Placental Flow, Placental Malperfusion Defects, and Impaired Growth.
Josowitz R, Ho DY, Shankar S, Mondal A, Zavez A, Linn RL, Tian Z, Gaynor JW, Rychik J., JACC Adv 4(2): 101559, 2025, PMID:39898349
Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline
Cheng K, Seita Y, Whelan EC, Yokomizo R, Hwang YS, Rotolo A, Krantz ID, Ginsberg JP, Kolon TF, Lal P, Luo X, Pierorazio PM, Linn RL, Ryeom S, Sasaki K., Cell Reports 43(6): 114323, 2024
Case report of fetus with Lowe syndrome: Expanding the prenatal phenotype
Burrill N, Khalek N, Oliver ER, Linn R, Victoria T, Yates C, Moldenhauer JS., Prenat Diagn 44(5): 665-668, 2024, PMID:38554254
Progesterone for Neurodevelopment in Fetuses With Congenital Heart Defects: A Randomized Clinical Trial
Gaynor JW, Moldenhauer JS, Zullo EE, Burnham NB, Gerdes M, Bernbaum JC, D'Agostino JA, Linn RL, Klepczynski B, Randazzo I, Gionet G, Choi GH, Karaj A, Russell WW, Zackai EH, Johnson MP, Gebb JS, Soni S, DeBari SE, Szwast AL, Ahrens-Nicklas RC, Drivas TG, Jacobwitz M, Licht DJ, Vossough A, Nicolson SC, Spray TL, Rychik J, Putt ME., JAMA Network Open 7(5): e2412291, 2024, PMID:38805228
Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19
Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA., bioRxiv, 2024, PMID:38464046
Neonatal Hemochromatosis in a Fetus with De Novo PTEN Mutation: An Autopsy Case Report and Literature Review
Fang Bian, Yan Feng, Julia Angel, Rebecca L Linn., Society for pediatric pathology 2024 spring meeting. Baltimore, MD., 2024
The Placenta in Congenital Heart Disease: Form, Function and Outcomes
Josowitz R, Linn R, Rychik J., Neoreviews 24(9): e569-e582, 2023