The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection.

Hayeck, T. J., Li, Y., Mosbruger, T. L., Bradfield, J. P., Gleason, A. G., Damianos, G., Shaw, G. T.-W., Duke, J. L., Conlin, J. L., Turner, T. N., Fernández-Viña, M. A., Sarmady, M., & Monos, D. S., Genome Biology and Evolution 1;16(2): , 2024, PMID:38302106

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Polygenic Risk Scores: Genomes to Risk Prediction

Tristan Hayeck, CLINICAL CHEMISTRY PODCAST, 2023

A combination of HLA-DP α and β chain polymorphisms paired with a SNP in the DPB1 3' UTR region, denoting expression levels, are associated with atopic dermatitis.

Margolis DJ, Duke JL, Mitra N, Berna RA, Hoffstad OJ, Wasserman JR, Dinou A, Damianos G, Kotsopoulou I, Tairis N, Ferriola DA, Mosbruger TL, Hayeck TJ, Yan AC, Monos DS, Front Genet. 23(14): , 2023, PMID:36911412

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Polygenic Risk Scores: Genomes to Risk Prediction.

Hayeck TJ, Busby GB, Chun Sung, Lewis ACF, Roberts MC, BJ Vilhjálmsson, Clinical Chemistry 69(6): 551-557, 2023

Ancestry adjustment improves genome-wide estimates of regional intolerance.

Hayeck, T.J., Stong, N., Baugh, E., Dhindsa, R., Turner, T.N., Malakar, A., Mosbruger, T.L., Duan, Y., Ionita-Laza, I., Goldstein, D. and Allen, A.S, Genetics 221(2): iyac050, 2022, PMID:35385101

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Complex Linkage Disequilibrium Effects in HLA-DPB1 Expression and Molecular Mismatch Analyses of Transplantation Outcomes.

Shieh M, *Hayeck TJ, Dinh A, Duke JL, Chitnis N, Mosbruger T, Morlen RP, Ferriola D, Kneib C, Hu T, Huang Y, Monos DS, Transplantation 105(3): 637-647, 2021

Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism.

Padhi EM, Hayeck TJ, Cheng Z, Chatterjee S, Mannion BJ, Byrska-Bishop M, Willems M, Pinson L, Redon S, Benech C, Uguen K, Audebert-Bellanger S, Le Marechal C, Férec C, Efthymiou S, Rahman F, Maqbool S, Maroofian R, Houlden H, Musunuri R, Narzisi G, Abhyankar A, Hunter RD, Akiyama J, Fries LE, Ng JK, Mehinovic E, Stong N, Allen AS, Dickel DE, Bernier RA, Gorkin DU, Pennacchio LA, Zody MC, Turner TN, Hum Genomics 15(1): 44, 2021

Improved Pathogenic Variant Localization via a Hierarchical Model of Sub-regional Intolerance.

Hayeck, T. J., Stong, N., Wolock, C. J., Copeland, B., Kamalakaran, S., Goldstein, D.B., & Allen, A. S, The American Journal of Human Genetics 104(2): 299-309, 2019

Mixed Model Association with Family-Biased Case-Control Ascertainment.

Hayeck, T J., et al., The American Journal of Human Genetics 100(1): 31-39, 2017

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Hayeck, T.J. Price, A. L., The American Journal of Human Genetics 97(4): 576-592, 2015