PEOPLE

Elizabeth M. Margolskee, MD, MPH

Associate Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information3401 Civic Center Boulevard
Philadelphia, PA, 19104
Office: 6316808643

Specialty Division

Hematopathology

Other Expertise

On my first day as a lab director, I learned that our entire dayshift staff had been exposed to COVID-19 in the workplace and had to quarantine. Although no one became seriously ill, this experience framed my relationship with laboratory professionals, and highlighted their role as front line workers.

I work closely with Surabhi Mulchandani, Vice Chair for Laboratory Administration, and other leadership in the department, to develop sustainable, ongoing strategies to develop and strengthen the pathology workforce.

Clinical Expertise

I am a hematopathologist and Director of the hematology laboratory at Children's Hospital of Philadelphia. I came to hematopathology originally because I wanted to care for critically ill patients alongside intelligent, curious clinicians in a collaborative fashion. I also enjoy interacting with our strong flow cytometrists, medical technologists, molecular pathologists, cytogeneticists, histotechs and pathology assistants, who make my work possible.

I am interested in quality and process improvement in the lab, and I am particularly fascinated by pediatric myeloid neoplasms.

Education

AB Harvard University, Cambridge, MA, 2006
MD Mount Sinai School of Medicine, New York, NY, 2010
MPH (Epidemiology), Columbia University Mailman School of Public Health, 2014

Specialty Certification

American Board of Pathology, Anatomic and Clinical Pathology, 2015
American Board of Pathology, Hematopathology, 2016

Postgraduate Training

Resident, Anatomic/Clinical Pathology, NYPH-Columbia University Medical Center, New York, NY, 2010-2015
Chief Resident, Anatomic/Clinical Pathology NYPH-Columbia University Medical Center, New York, NY, 2012-2013
Fellow, Hematopathology, NYPH-Weill Cornell, New York, NY, 2015-2016

Awards and Honors

Hoopes Prize for Senior thesis, 2006
Vermeule Prize for excellence in Archaeological Scholarship, 2006
Honorable Mention: Gold Foundation Humanism in Medicine Essay Contest, 2009
Wyman Scholar at Mailman School of Public Health, 2013
American Society of Hematology Abstract Achievement Award, 2013
American Society of Hematology Abstract Achievement Award, 2015
Best Podium Presentation, 8th Annual CHOP Education Day, 2025

Memberships and Professional Organizations

United States & Canadian Academy of Pathology, 2012 - Present
College of American Pathologists, 2016 - Present
AIDS Malignancies Consortium, 2017 - 2019
Society for Hematopathology, 2018 - Present
American Society for Clinical Pathology, 2022 - Present

Web Links


Selected Publications

District Implementation Guide: Building CTE Pathways in Laboratory Medicine

Holly Hatch, American Society for Clinical Pathology, 2026

An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Elizabeth Margolskee, Robert Klenk, Tracey Polsky, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

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An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Elizabeth Margolskee, Robert Klenk, Tracey Polsky, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

Read article

An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Margolskee E, Klenk R, Polsky T, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

Read article

An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Elizabeth Margolskee, Robert Klenk, Tracey Polsky, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

Read article

An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Elizabeth Margolskee, Robert Klenk, Tracey Polsky, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

Read article

An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients

Elizabeth Margolskee, Robert Klenk, Tracey Polsky, American Journal of Clinical Pathology 164(5): 806-812, 2025, PMID:40995972

Read article

Benchmarking Transformer Embedding Models for Biomedical Terminology Standardization

Lahiri A, Shukla S, Stear B, Ahooyi TM, Beigel K, Margolskee E, Taylor D., Mach Learn Appl 21(): 100683, 2025

EBV-Negative CD20+ Plasma Cell Posttransplant Lymphoproliferative Disorder of the Airway following Liver Transplant in a 16-Month Old

Zheng DJ, Margolskee E, Borek RC, Devine KJ., Pediatr Blood Cancer 79(9): e31901, 2025

Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists

Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Surrey LF, Margolskee E, Pillai V, Luo M, Paessler ME, Hunger SP, Li MM, Zhong Y., Haematologica 110(8): 1861-1864, 2025