Kenneth Patrick Smith, PhD

Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact InformationChildren's Hospital of Philadelphia
Infectious Disease Diagnostics Laboratory
Department of Pathology and Laboratory Medicine
5th Floor, Main Building, 5NW91
Philadelphia, PA, 19104


BS (Biology), Westfield State University, 2007
MS (Biology), Eastern New Mexico University, 2010
PhD (Microbiology and Molecular Genetics), University of Vermont, 2015

Specialty Certification

American Board of Medical Microbiology (ABMM), 2020

Postgraduate Training

Postdoctoral Fellow Translational clinical microbiology, Kirby Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 2015-2020
American Society for Microbiology Continuing Professional Education Programs (ASM CPEP) Medical and Public Health Microbiology Fellow, Beth Israel Deaconess Medical Center, 2018-2020

Awards and Honors

Academic Excellence Award - Westfield State University Biology Department, 2007
1st Place, Biology Graduate Student Research Conference - Eastern New Mexico University, 2009
2nd Place, Graduate Student Poster Competition - University of Vermont College of Medicine, 2012
Society for Laboratory Automation and Screening (SLAS)2017 Innovation Award Finalist - Society for Laboratory Automation and Screening, 2017
Student and Postdoctoral Fellow Travel Award - American Society for Microbiology, 2017
Outstanding Abstract Award - American Society for Microbiology, 2018
Society for Laboratory Automation and Screening,Digital Health 2019 Early-Career Member Contest Winner, 2019
Paul E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Clinicians and Scientists, Salt Lake City, UT, 2019

Memberships and Professional Organizations

American Society for Microbiology, 2015 - Present
Society for Laboratory Automation and Screening, 2018 - 2019
Academy of Clinical Laboratory Physicians and Scientists, 2019 - 2020
Clinical and Laboratory Standards Institute Document Development Committee on Verifying ID/AST Systems (M52), 2020 - Present
CHOP Infection Prevention and Control Healthcare Acquired Infections (IP&C/HAI) Steering Committee, 2021 - Present
American Board of Medical Microbiology Exam Validation Subcommittee, 2021 - Present
CHOP Antibiotic Drug Use Evaluation (ADUE) Subcommittee, 2021 - Present

Web Links

Selected Publications

The convergent total synthesis and antibacterial profile of the natural product streptothricin F

Dowgiallo M., Miller B., Kassu M., Smith K.P., Fetigan A., Guo J., Kirby J.E., and Manetsch R., Chemical Science 13(): 3447-3453 , 2022

Listeria and Erysipelothrix

Smith K.P. and Harris R.M., Manual of Clinical Microbiology, 2022

Novel assays for molecular detection of SARS-CoV-2

Rodino K.G., Smith K.P., Pettengill M.A., Clinics in Laboratory Medicine, 2022

Pyrazole-Thiazole Core-Containing Analogs Exhibit Adjunctive Activity with Meropenem against Carbapenem-Resistant Enterobacteriaceae (CRE)

Kim C, Kassu M, Smith KP, Kirby JE, Manetsch R, ChemMedChem Accepted(): , 2021

A Brief History of Tuberculosis Diagnostics

Kenneth P. Smith, American Society for Microbiology Bugs and Drugs Blog, 2021

The Limit of Detection Matters: The Case for Benchmarking Severe Acute Respiratory Syndrome Coronavirus 2 Testing

Arnaout R, Lee RA, Lee GR, Callahan C, Cheng A, Yen CF, Smith KP, Arora R, Kirby JE, Clinical Infectious Diseases, 2021

Large-Scale, In-House Production of Viral Transport Media To Support SARS-CoV-2 PCR Testing in a Multihospital Health Care Network during the COVID-19 Pandemic.

Smith KP, Cheng A, Chopelas A, DuBois-Coyne S, Mezghani I, Rodriguez S, Talay M, Kirby JE, Journal of Clinical Microbiology 58(8): e00913-20, 2020

Open Development and Clinical Validation of Multiple 3D-Printed Nasopharyngeal Collection Swabs: Rapid Resolution of a Critical COVID-19 Testing Bottleneck

Callahan CJ, Lee R, Zulauf KE, Tamburello L, Smith KP, Previtera J, Cheng A, Green A, Abdul Azim A, Yano A, Doraiswami N, Kirby JE, Arnaout RA., Journal of Clinical Microbiology 58(8): e00876-20, 2020

Applications of Artificial Intelligence in Clinical Microbiology Diagnostic Testing

Smith K.P., Wang H., Durant T.J.S., Mathison B.A., Sharpe S., Kirby J.E., Long S.W., and Rhoads D.D., Clinical Microbiology Newsletter 42(): 61-70, 2020

Bringing Antimicrobial Susceptibility Testing for New Drugs into the Clinical Laboratory: Removing Obstacles in our Fight Against Multidrug-resistant Pathogens.

Kirby J.E., Brennan-Krohn T., Smith K.P., Journal of Clinical Microbiology 57(12): e01270-19, 2019