PEOPLE

Parker C. Wilson, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information

Email: parker.wilson@pennmedicine.upenn.edu

Specialty Division

Anatomic Pathology, Cancer and Immunobiology

Education

BS (Engineering with a Concentration in Computer Science), Johns Hopkins University, 2005
MD, PhD (Molecular and Cellular Biology and Pathobiology), Medical University of South Carolina, 2013

Specialty Certification

American Board of Pathology - Anatomic and Clinical Pathology, 2017
American Board of Pathology - Molecular Genetic Pathology, 2021

Postgraduate Training

Residency, Anatomic and Clinical Pathology, Yale New Haven Hospital, 2013-2017
Clinical Fellowship, Renal and Genitourinary Pathology, Yale New Haven Hospital, 2017-2018
Clinical Fellowship, Molecular Genetic Pathology, Washington University School of Medicine, St. Louis, MO, 2018-2019

Awards and Honors

Harvard-MIT National Science Foundation Research Fellow, 2004
Ruth L. Kirschstein Individual Predoctoral National Research Service Award (F30), 2011-2012
Chairman’s Challenge Grant for Mentored Research in Residency, 2014-2017
American Society of Nephrology Kidney STAR Travel Grant, 2015
Kidney Precision Medicine Project Travel Grant, Washington University School of Medicine, 2018
Best AP Oral Abstract Trainee Research Day, Washington University School of Medicine, 2019
Diabetes Research Center Symposium Best Oral Abstract in Basic Science Category, Washington University School of Medicine, 2020
NIH NIDDK K08 Career Development Award, 2022-2026
Young Physician Scientist Award - American Society of Clinical Investigation, 2023

Memberships and Professional Organizations

United States and Canadian Academy of Pathology, 2013 - Present
American Society of Nephrology, 2015 - Present
Renal Pathology Society, 2018 - Present
Association for Molecular Pathology, 2019 - Present
ClinGen Glomerulopathy and Cystic Kidney Disease Gene Curation Expert Panel, 2021 - Present

Web Links


Selected Publications

Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs

Han SK, McNulty MT, Benway CJ, Wen P, Greenberg A, Onuchic-Whitford AC; Nephrotic Syndrome Study Network (NEPTUNE); Jang D, Flannick J, Burtt NP, Wilson PC, Humphreys BD, Wen X, Han Z, Lee D, Sampson MG., Nat Commun 14(): 2229, 2023, PMID:37076491

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Quality assessment and refinement of chromatin accessibility data using a sequence-based predictive model

Han SK, Muto Y, Wilson PC, Humphreys BD, Sampson MG, Chakravarti A, Lee D., Proc Natl Acad Sci U S A 119(): e2212810119, 2022, PMID:36508674

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Concordance in Breast Cancer Grading by Artificial Intelligence on Whole Slide Images Compares With a Multi-Institutional Cohort of Breast Pathologists

Mantrala S, Ginter PS, Mitkari A, Joshi S, Prabhala H, Ramachandra V, Kini L, Idress R, D'Alfonso TM, Fineberg S, Jaffer S, Sattar AK, Chagpar AB, Wilson P, Singh K, Harigopal M, Koka D., Arch Pathol Lab Med 146(): 1369-1377, 2022, PMID:35271701

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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

Muto Y, Dixon EE, Yoshimura Y, Wu H, Omachi K, Ledru N, Wilson PC, King AJ, Eric Olson N, Gunawan MG, Kuo JJ, Cox JH, Miner JH, Seliger SL, Woodward OM, Welling PA, Watnick TJ, Humphreys BD., Nat Commun 13(): 6497, 2022, PMID:36310237

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Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression

Wilson PC, Muto Y, Wu H, Karihaloo A, Waikar SS, Humphreys BD., Nat Commun 13(): 5253, 2022, PMID:36068241

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Neuroblastoma suppressor of tumorigenicity 1 is a circulating protein associated with progression to end-stage kidney disease in diabetes

Kobayashi H, Looker HC, Satake E, D'Addio F, Wilson JM, Saulnier PJ, Md Dom ZI, O'Neil K, Ihara K, Krolewski B, Badger HS, Petrazzuolo A, Corradi D, Galecki A, Wilson PC, Najafian B, Mauer M, Niewczas MA, Doria A, Humphreys BD, Duffin KL, Fiorina P, Nelson RG, Krolewski AS., Sci Transl Med 14(): eabj2109, 2022, PMID:35947673

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Understanding How Genetic Background Affects Kidney Function at the Single-Cell Level.

Wilson PC, Humphreys BD, Am J Kidney Dis. 79(4): 613-615, 2022

How Whole Slide Imaging and Machine Learning Can Partner with Renal Pathology

Wilson PC, Messias N., Kidney360 3(): 413-415, 2022, PMID:35582192

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Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model

Dixon EE, Wu H, Muto Y, Wilson PC, Humphreys BD., J Am Soc Nephrol 33(2): 279-289, 2022, PMID:34853151

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Mutational fingerprints reconstruct human cell genealogies.

Wilson PC, Humphreys BD, Nat Rev Nephrol 18(1): 6-7, 2022