PEOPLE

Jina Ko, PhD

Assistant Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Contact Information422 Curie Blvd
Philadelphia, PA, 19104-4283

Email: Jina.Ko@Pennmedicine.upenn.edu

Specialty Division

Cancer and Immunobiology

Research Expertise

Medical Diagnostics, Droplet Microfludiics, Biomarker Discovery, Microfabrication

Itmat Expertise

Next Generation Tools for Medical Diagnostic
Single Extracellular Vesicle Analysis
Biomarker Discovery for Neurological Disorders

Education

B.S. Rice University, 2013
Ph.D. University of Pennsylvania, 2018

Specialty Certification

Postgraduate Training

Schmidt Science Postdoctoral Fellow, Massachusetts General Hospital & Harvard Medical School, 2018-2020
Instructor, NIH NCI K99/R00 Fellow, Massachusetts General Hospital & Harvard Medical School, 2021-2022

Awards and Honors

President’s Honor Roll, Rice University, 2010
Pi Delta Phi: National French Honor Society, 2011
Research Scholarship, École Nationale Supérieure des Mines de St-Étienne, 2012
Singh Center for Nanotechnology Annual User Meeting, 1st Prize, University of Pennsylvania, 2015
Bioengineering Graduate Group Symposium, 3rd Prize,
University of Pennsylvania, 2016
Lab on a Chip Widmer Award Winner, MicroTAS, 2017
Sol Pollack Award (Best thesis of the year), University of Pennsylvania, 2018
Schmidt Science Fellows, in Partnership with the Rhodes Trust, 2018
Keystone Symposia Future of Science Fund Scholarship, 2018
MicroTAS 2019 Travel Grant, 2019
ISEV2020 Young Investigator Scholarship, 2020
Rising Stars in Engineering in Health at Columbia University, 2020
NIH K99/R00 NCI Pathway to Independence Award (Impact score: 10), 2021-2026
Presidents Award for Excellence at CYTO, 2022
NIH Director's New Innovator Award (DP2), 2023
KBMES Young Investigator Award, 2024

Memberships and Professional Organizations

National Institute of Health, 2023 - 2023
University of Pennsylvania, 2023 - Present
National Institute of Health, 2023 - 2023
University of Pennsylvania, 2024 - Present
National Institute of Health, 2024 - 2024

Web Links


Selected Publications

Squeezable Hydrogel Microparticles for Single Extracellular Vesicle Protein Profiling

Y. Roh*, RT. Morales*, E. Huynh, U. Chintapula, D.E. Reynolds, R.J. Agosto Nieves, D. Oh, A.J. Seiner, J. Lim, C. B. Rodell, J. Ko, Small, 2024

Live Organoid Cyclic Imaging

D.E. Reynolds, Y. Sun, X. Wang, P. Vallapureddy, J. Lim, M. Pan, A. Fernadez Del Castillo, J. C. T. Carlson, M. A. Sellmyer, M. Nasrallah, Z. Binder, D. M. O’Rourke, G. Ming, H. Song, J. Ko, Advanced Science, 2024

Increasing Cell Therapeutic Potential by Selecting Cells with High Extracellular Vesicle Secretion

D. Koo, X. Cheng, S. Udani, D. Zhu, J. Li, B. Hall, N. Tsubamoto, J. Ko, K. Cheng, D. Di Carlo, Nature Communications, 2024

A Versatile Microchannel Array Device for Portable and Parallel Droplet Generation

Z. Tang, D.E. Reynolds, C. Lv, D. Zhang, J. Ko, Y. Wang, Small Science, 2024

Droplet and Digital Microfluidics: Ideation to Implementation

D.E. Reynolds, J. Lim, Y. Roh, U. Chintapula, RT. Morales, D. Oh, J. Ko, Elsevier, 2024

Anti-cancer bioactivity of sweet basil leaf derived extracellular vesicles on pancreatic cancer cells

U. Chintapula, D. Oh, C. Perez, S. Davis, J. Ko, Journal of Extracellular Biology, 2024

Single Extracellular Vesicle Analysis using Droplet Microfluidics

D.E. Reynolds, G. Galanis, J. Ko, Methods Mol Biol, Springer Nature, 2023

Patient-Derived Melanoma Organoid Models Facilitate the Assessment of Immunotherapies

L. Ou, S. Liu, H. Wang, Y. Guo, L. Guan, L. Shen, R. Luo, D. Elder, A. Huang, G. Karakousis, J. Miura, T. Mitchell, L. Schuchter, R. Amaravadi, A. Flowers, H. Mou, Y. Fan, W. Guo, J. Ko, Q. Chen, B. Tian, M. Herlyn, X. Xu, eBiomedicine, 2023

Single-cell and spatially resolved omics: Advances and Limitations

J. Chen, J. Ko, Y. Wang, Journal of Pharmaceutical Analysis, 2023

Highly Parallel, Wash-free, and Ultrasensitive Centrifugal Droplet Digital Protein Detection in Sub-Microliter Blood

Z. Tang, F. Lv, D.E. Reynolds, S. Zhang, S. Zheng, D. Zhang, J. Ko, Y, Chen, Y. Wang, Lab on a Chip, 2023