Giulia Pavani, PhD
Research Assistant Professor of Pathology and Laboratory MedicinePerelman School of Medicine at the University of Pennsylvania
Contact InformationChildren's Hospital of Philadelphia
3501 Civic Center Blvd.
Colket Building, Rm. 10050
Philadelphia, PA, 19104
Office: 2674261222
Email: PAVANIG@chop.edu
Research Expertise
Induced Pluripotent stem cells, hematopoiesis, Gene editing
Education
BA (Cell and Molecular Biology), University of Ferrara, Ferrara, Italy, 2008
BS (Molecular and Cellular Biotechnologies), University Vita-Salute S.Raffaele, Milan, Italy, 2010
PhD (Molecular Biology and Biotechnology), University of Ferrara, Ferrara, Italy, 2014
Specialty Certification
Postgraduate Training
Postdoctoral Fellow, Gene Editing Research, Genethon, Evry, France, 2015-2019
Awards and Honors
Doctoral Dissertation Award, University Institute for Higher Studies - IUSS Ferrara 1391,, 2014
Nicolò Copernico thesis award, for innovative theses in sciences and technologies, 2014
Martin Villar Haemostasis Award, Basic Research, 2015
American Society of Gene and Cell Therapy, Excellence in research award, 2018
Memberships and Professional Organizations
American Society of Hematology, 2012 - Present
American Society for Cell and Gene Therapy, 2015 - Present
International Society for Stem Cell Research, 2021 - Present
The Netherlands Organisation for Health Research and Development (ZonMw), 2024 - 2024
Stem Cell COREdinates, 2024 - Present
Austrian Science Fund (FWF), 2025 - 2026
Web Links
Selected Publications
Production of Induced Pluripotent Stem Cell-Derived Red Blood Cells
Hyun Hyung An, Giulia Pavani, Stella T. Chou, Methods Molecular Biology, (Eds): Methods in Transfusion Medicine 3053(): , 2026
Synergistic cooperation between Progranulin and Jak2/Stat3 signaling determines definitive myeloid cell fate
Abbigail McCune, Masuma Khatun Usha, Inga Baldus, CJ Willett, Noemi Ferrito, Radwa Barakat, Emilee Clemensen, Elizabeth Snella, Mark Morton, Jesus Lacal, Giulia Pavani, Clyde A Campbell and Raquel Espin-Palazon, Cell Reports, 2026
An iPSC Model of Thrombocytopenia Absent Radius Syndrome Links Aberrant Splicing to Impaired Megakaryopoiesis
Catriana C Nations,, Jenea I Adams, Nicole Debruyne,, Xiuli Sim,, Hyun Sook Ahn,CJ Willett , James Warland, Cedric Ghevaert, Kathleen Freson, Giulia Pavani, Deborah LFrench, Mortimer Poncz, Yi Xing, Lan Lin, and Paul J Gadue, Blood Vessels, Thrombosis & Hemostasis, 2026
Rare antigen negative red blood cells from pluripotent stem cells for precision transfusion medicine
Naomi Gunawardena, Hyun Hyung An, Randall W. Veliquette, Edmund Carvalho, Sambit Dalui, Kaoru Takasaki, Eric Wafula, Deborah L. French, Giulia Pavani, Stella T. Chou, Transfusion, 2026
Generation of CHOPi014-A from healthy adult peripheral blood mononuclear cells
Alyssa L. Gagne, Jean Ann Maguire, Lea Dungan, Paul Gadue, Deborah L. French, Giulia Pavani, Stem Cell Research 88(): 103820, 2025
Advanced Imaging and Cytometric Techniques to Characterize Lipid Accumulation in Wolman Disease
Laurent M, Cosette J, Pavani G, Bayol S, Jenny C, Harb R, Oustelandt J, Brassier A, Stockholm D, Amendola M., Cytometry A. 107(7): 464-475, 2025
Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis.
Wilken MB, Fonar G, Qiu R, Bennett L, Tober J, Nations C, Pavani G, Tsao V, Garifallou J, Petit C, Maguire JA, Gagne A, Okoli N, Gadue P, Chou ST, French DL, Speck NA, Thom CS., Stem Cell Reports 19(9): 1264-1276, 2024, PMID:39214082
p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulation.
Campbell CA, Calderon R, Pavani G, Cheng X, Barakat R, Snella E, Liu F, Peng X, Essner JJ, Dorman KS, McGrail M, Gadue P, French DL, Espin-Palazon R., Nat Commun 15(1): 7787, 2024, PMID:39242546
CRISPR-Based Gene Therapies: From Preclinical to Clinical Treatments.
Laurent M, Geoffroy M, Pavani G, Guiraud S., Cells 8(13): 800, 2024, PMID:38786024
Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells
Pavani G, Klein JG, Nations CC, Sussman JH, Tan K, An HH, Abdulmalik O, Thom CS, Gearhart PA, Willett CM, Maguire JA, Chou ST, French DL, Gadue P., Blood Adv 26(8): 1449-1463, 2024, PMID:38290102
