Timothy Hue-Fung Chao, MD, PhD
Assistant Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Director, Hematology, Pennsylvania Hospital
Contact InformationPennsylvania Hospital
Department of Pathology and Laboratory Medicine
Spruce Building, 10th Floor
801 Spruce Street
Philadelphia, PA 19107
Tel: 215-829-7092
Specialty Division
Anatomic Pathology
Clinical Expertise
Gastrointestinal Pathology, Hepatopancreatobiliary Pathology, Head and Neck Pathology
Education
BS (Bioengineering), University of Washington, 2008
BA (Biochemistry), University of Washington, 2008
PhD (Philosophy), Perelman School of Medicine at the University of Pennsylvania, 2017
MD (Medicine), Perelman School of Medicine at the University of Pennsylvania, 2019
Specialty Certification
Anatomic and Clinical Pathology, American Board of Pathology, 2023
Postgraduate Training
Resident, Anatomic and Clinical Pathology, Thomas Jefferson University Hospital, 2019-23
Fellow, Gastrointestinal and Liver Pathology, Hospital of the University of Pennsylvania, 2023-24
Awards and Honors
Dean's List/University of Washington, 2003-08
UW Honors General Chemistry Achievement Award, University of Washington, 2004
Mary Gates Research Scholarship, University of Washington, 2006-07
UW College of Engineering's Clayton and Helen Danner Endowed Scholarship, University of Washington, 2006-07
Stowell-Orbison Certificate of Merit, United States and Canadian Academy of Pathology (USCAP) Honors, 2020 & 2021
Department of Pathology and Genomic Resident Scholar Award, Thomas Jefferson University Hospital, 2023-23
Memberships and Professional Organizations
Pathology Society of Philadelphia, Executive Committee, 2022-present
College of American Pathologists, 2022-present
United States and Canadian Academy of Pathology, 2022-present
Digital Pathology Association
Web Links
Selected Publications
A rare metastatic mesenteric malignant PEComa with TSC2 mutation treated with palliative surgical resection and nab-sirolimus: a case report
Meredith L, Chao T, Nevler A, Basu Mallick A, Singla RK, McCue PA, Bowne WB, Jiang W. Diagnostic Pathology 18(1): 45, 2023. PMID:37041531
Modern Blood Culture: Management Decisions and Method Options
Gonzalez MD, Chao T, Pettengill MA. Clinics in Laboratory Medicine 40(4): 379-392, 2020. PMID:33121610
PD-L1 positivity associated with presence of tertiary lymphoid structures and high-stage disease in upper tract urothelail carcinoma
Smith ME, Farahani SJ, Chao T, Palmer M, Arriola A., Lal P. American Journal of Clinical Pathology 154(6): 802-810, 2020. PMID:32864684
Subependymal giant cell astrocytoma without clinically or genetically identifiable tuberous sclerosis complex: a case report.
Hafazalla K, Ye DY, Chao T, Curtis M, Farrell CJ. Case Reports and Series in Surgery 1(2): 1-4, 2020.
CSF Cytokine Profiles Help Discriminate CNS Tumors, Lymphomas, Autoimmune Diseases, and Infections
Chao T, Fortuna D, Kean R, Hooper D, Nagurney M, Curtis M. Laboratory Investigation 100(Suppl 1): 1605, 2020.
Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy.
Li J, Byrne KT, Yan F, Yamazoe T, Chen Z, Baslan T, Richman LP, Lin JH, Sun YH, Rech AJ, Balli D, Hay CA, Sela Y, Merrell AJ, Liudahl SM, Gordon N, Norgard RJ, Yuan S, Yu S, Chao T, Ye S, Eisinger-Mathason TSK, Faryabi TB, Tobias JW, Lowe SW, Coussens LM, Wherry EJ, Vonderheide RH, Stanger BZ. Immunity 49(1): 178-193.e7., 2018. PMID:29958801
Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors
Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla-Alonso S, Hashimoto A, Vonteddu P, Behera R, Goins MA, Mulligan C, Nam B, Hockstein N, Denstman F, Shakamuri S, Speicher DW, Weeraratna AT, Chao T, Vonderheide RH, Languino LR, Ordentlich P, Liu Q, Xu X, Lo A, Pure E, Zhang C, Loboda A, Sepulveda MA, Snyder LA, Gabrilovich DI. Cancer Cell 32(5): 654-668, 2017. PMID:29136508
CXCR2-dependent accumulation of tumor-associated neutrophils regulates T-cell immunity in pancreatic ductal adenocarcinoma
Chao T, Furth EE, Vonderheide RH. Cancer Immunology Research 4(11): 968-982, 2016. PMID:27737879
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
Evans R, Diamond M, Rech A, Chao T, Richardson M, Lin J, Bajor D, Byrne K, Stanger B, Riley J, Markosyan N, Winograd R, Vonderheide RH. Journal of Clinical Investigation Insight 1(14): e88328, 2016. PMID:27642636
An Autoimmune Response Signature Associated with the Development of Triple-Negative Breast Cancer Reflects Disease Pathogenesis
Katayama H, Boldt C, Ladd JJ, Johnson MM, Chao T, Capello M, Suo J, Mao J, Manson JE, Prentice R, Esteva F, Wang H, Disis ML, Hanash S. Cancer Research 75(16): 3246-54, 2015. PMID:26088128
