Zhi Huang, PhD
Assistant Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact InformationPerelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
Richards Building, Rm D204
3700 Hamilton Walk
Philadelphia, PA 19104
Email: zhi.huang@pennmedicine.upenn.edu
Specialty Division
Diagnostic Innovation
Research Expertise
Artificial Intelligence, Medical Image Analysis, Digital Pathology, Diagnostic Innovation, Computational Medicine, Large Language Model
Education
BS (Automation), Xi’an Jiaotong University, 2015
MS (Electrical and Computer Engineering), Purdue University, Indianapolis, 2016
PhD (Electrical and Computer Engineering), Purdue University, West Lafayette, 2021
Postgraduate Training
Research Intern, Philips Research North America, 2019
Postdoctoral Fellow, Stanford University, 2021-24
Awards and Honors
Stanford Medicine Department of Pathology Award for Innovations and Publications, 2023
Web Links
Selected Publications
Huang Z, Yang E, Shen J, Gratzinger D, Eyerer F, Liang B, Nirschl J, Bingham D, Dussaq AM, Kunder C, Rojansky R, Gilbert A, Chang-Graham AL, Howitt BE, Liu Y, Ryan EE, Tenney TB, Zhang X, Folkins A, Fox EJ, Montine KS, Montine TJ, Zou J.: A pathologist-AI collaboration framework for enhancing diagnostic accuracies and efficiencies. Nat Biomed Eng no volume(no issue), Jun 2024 Notes: doi: 10.1038/s41551-024-01223-5.
Liu R, Wang L, Rizzo S, Garmhausen MR, Pal N, Waliany S, McGough S, Lin YG, Huang Z, Neal J, Copping R, Zou J.: Systematic analysis of off-label and off-guideline cancer therapy usage in a real-world cohort of 165,912 US patients. Cell Rep Med 5(3): 101444, Mar 2024 Notes: doi: 10.1016/j.xcrm.2024.101444. Epub 2024 Feb 29.
Montine KS, Berson E, Phongpreecha T, Huang Z, Aghaeepour N, Zou JY, MacCoss MJ, Montine TJ.: Understanding the molecular basis of resilience to Alzheimer's disease. Front Neurosci 17(no issue): 1311157, Dec 2023 Notes: doi: 10.3389/fnins.2023.1311157.
Huang Z, Merrihew GE, Larson EB, Park J, Plubell D, Fox EJ, Montine KS, Keene CD, Latimer CS, Zou JY, MacCoss MJ, Montine TJ.: Unveiling Resilience to Alzheimer's Disease: Insights From Brain Regional Proteomic Markers. Neurosci Insights 18(no issue): 26331055231201600, Oct 2023 Notes: doi: 10.1177/26331055231201600. eCollection 2023.Comment.
Huang Z, Bianchi F, Yuksekgonul M, Montine TJ, Zou J.: A visual-language foundation model for pathology image analysis using medical Twitter. Nat Med 29(9): 2307-2316, September 2023 Notes: doi: 10.1038/s41591-023-02504-3.
Huang Z, Merrihew GE, Larson EB, Park J, Plubell D, Fox EJ, Montine KS, Latimer CS, Dirk Keene C, Zou JY, MacCoss MJ, Montine TJ.: Brain proteomic analysis implicates actin filament processes and injury response in resilience to Alzheimer's disease. Nat Commun 14(1): 2747, May 2023 Notes: doi: 10.1038/s41467-023-38376-x.
Huang Z, Shao W, Han Z, Alkashash AM, De la Sancha C, Parwani AV, Nitta H, Hou Y, Wang T, Salama P, Rizkalla M, Zhang J, Huang K, Li Z.: Artificial intelligence reveals features associated with breast cancer neoadjuvant chemotherapy responses from multi-stain histopathologic images. NPJ Precis Oncol 7(1): 14, January 2023 Notes: DOI: 10.1038/s41698-023-00352-5.
Liu R, Rizzo S, Waliany S, Garmhausen MR, Pal N, Huang Z, Chaudhary N, Wang L, Harbron C, Neal J, Copping R, Zou J.: Systematic pan-cancer analysis of mutation-treatment interactions using large real-world clinicogenomics data. Nat Med 28(8): 1656-1661, August 2022 Notes: doi: 10.1038/s41591-022-01873-5. Epub 2022 Jun 30.
