Rajendra Singh, MBBS
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact InformationHospital of the University of Pennsylvania
Department of Pathology and Laboratory Medicine
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Email: rajendra.singh@pennmedicine.upenn.edu
Specialty Division
Anatomic Pathology
Clinical Expertise
Dermatopathology, Digital Pathology, AI
Research Expertise
Melanoma, Adnexal neoplasms, Digital Pathology, AI
Education
MBBS Medical College Baroda, 1991
Specialty Certification
Anatomic Pathology, American Board of Pathology, 2006
Dermatopathology, American Board of Pathology, 2006
Postgraduate Training
Resident, Anatomic and Clinical Pathology, Baroda Medical College, 1992-95
Postdoctoral Fellow, Department of Pathology, University of Alabama at Birmingham, 2002-03
Clinical Associate, Department of Pathology and Laboratory Medicine, Wayne State University, 2003-06
Resident, Anatomic Pathology, Wayne State University, 2003-06
Fellow, Dermatopathology, MD Anderson Cancer Center, 2006-07
Awards and Honors
Best Teacher Award, Pathology, University of Pittsburgh Medical Center (UPMC), 2011
Teacher of the Year Award, Dermatology, Mt. Sinai School of Medicine, 2012
Exceptional Achievement by Faculty Member, Pathology, Mt. Sinai School of Medicine, 2013
Teaching Excellence Award, Dermatology, Mt. Sinai School of Medicine, 2013, 2016-19
Mentor Par Excellence, Dermatology, Mt. Sinai School of Medicine, 2015
The Pathologist Magazine Power List, 2021, 2022, 2024
College of American Pathologists (CAP) Lifetime Achievement Award, 2022
College of American Pathologists (CAP) Meritorious Service Award, 2025
Memberships and Professional Organizations
American Society of Dermatopathology (ASDP), Ad Hoc Oversight Committee, 2015-16
World Health Organization (WHO), 2017-present
--- Co-Chair, WHO Digital Pathology Committee, 2024-present
American Academy of Dermatology (AAD), Sulzberger Grant Committee, 2020-present
Digital Pathology Association, Board Member, 2020-22
College of American Pathologists (CAP), Computational and Informatics Committee, 2022-present
Asian Society of Digital Pathology, Advisory Board, 2024-present
Web Links
Selected Publications
H2A.Z chaperones converge on E2F target genes for melanoma cell proliferation
Jostes S, Vardabasso C, Dong J, Carcamo S, Singh R, Phelps R, Meadows A, Grossi E, Hasson D, Bernstein E. Genes Dev 38(7-8):336-353, May 2024. doi: 10.1101/gad.351318.123. PMID: 38744503; PMCID: PMC11146596.
Challenges and barriers of using large language models (LLM) such as ChatGPT for diagnostic medicine with a focus on digital pathology - a recent scoping review
Ullah E, Parwani A, Baig MM, Singh R. Diagn Pathol 19(1):43, Feb 2024. doi: 10.1186/s13000-024-01464-7. PMID: 38414074; PMCID: PMC10898121.
From scope to screen: A collection of online dermatopathology resources for residents and fellows
Mukosera GT, Ibraheim MK, Lee MP, Elston D, Singh R, Ho J, Motaparthi K, Ahn CS, Lee BA, Gardner JM, Ferringer T, Elsensohn A. JAAD Int 12:12-14, Jan 2023. doi: 10.1016/j.jdin.2022.12.007. PMID: 37228363; PMCID: PMC10203758.
Federated learning for computational pathology on gigapixel whole slide images
Lu MY, Chen RJ, Kong D, Lipkova J, Singh R, Williamson DFK, Chen TY, Mahmood F. Med Image Anal 76:102298, Feb 2022. doi: 10.1016/j.media.2021.102298. Epub 2021 Nov 25. PMID: 34911013; PMCID: PMC9340569.
A Pathologist-Annotated Dataset for Validating Artificial Intelligence: A Project Description and Pilot Study
Dudgeon SN, Wen S, Hanna MG, Gupta R, Amgad M, Sheth M, Marble H, Huang R, Herrmann MD, Szu CH, Tong D, Werness B, Szu E, Larsimont D, Madabhushi A, Hytopoulos E, Chen W, Singh R, Hart SN, Sharma A, Saltz J, Salgado R, Gallas BD. J Pathol Inform 12:45, Nov 2021. doi: 10.4103/jpi.jpi_83_20. PMID: 34881099; PMCID: PMC8609287.
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
Kos Z, Roblin E, Kim RS, Michiels S, Gallas BD, Chen W, van de Vijver KK, Goel S, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS, Symmans WF, Sotiriou C, Rimm DL, Hewitt S, Denkert C, Loibl S, Luen SJ, Bartlett JMS, Savas P, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kok M, Horlings HM, Madabhushi A, van der Laak J, Ciompi F, Laenkholm AV, Bellolio E, Gruosso T, Fox SB, Araya JC, Floris G, Hudeček J, Voorwerk L, Beck AH, Kerner J, Larsimont D, Declercq S, Van den Eynden G, Pusztai L, Ehinger A, Yang W, AbdulJabbar K, Yuan Y, Singh R, et al. NPJ Breast Cancer 6:17, May 2020. doi: 10.1038/s41523-020-0156-0. PMID: 32411819; PMCID: PMC7217863.
SetSVM: An Approach to Set Classification in Nuclei-Based Cancer Detection
Liu C, Huang Y, Ozolek JA, Hanna MG, Singh R, Rohde GK. IEEE J Biomed Health Inform 23(1):351-361, Jan 2019. doi: 10.1109/JBHI.2018.2803793. Epub 2018 Feb 8. PMID: 29994380.
Meeting Report: The International Workshop on Harmonization and Standardization of Digital Pathology Image, Held on April 4, 2019 in Tokyo
Yoshida H, Yokota H, Singh R, Kiyuna T, Yamaguchi M, Kikuchi S, Yagi Y, Ochiai A. Pathobiology 86(5-6):322-324, 2019. doi: 10.1159/000502718. Epub 2019 Nov 8. PMID: 31707388.
SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling
Strub T, Ghiraldini FG, Carcamo S, Li M, Wroblewska A, Singh R, Goldberg MS, Hasson D, Wang Z, Gallagher SJ, Hersey P, Ma'ayan A, Long GV, Scolyer RA, Brown B, Zheng B, Bernstein E. Nat Commun 9(1):3440, AUg 2018. doi: 10.1038/s41467-018-05966-z. PMID: 30143629; PMCID: PMC6109055.
Predictive Nuclear Chromatin Characteristics of Melanoma and Dysplastic Nevi
Hanna MG, Liu C, Rohde GK, Singh R. J Pathol Inform 8:15, Apr 2017. doi: 10.4103/jpi.jpi_84_16. PMID: 28480118; PMCID: PMC5404351.
