Zubair W. Baloch, MD, PhD

Professor of Pathology and Laboratory Medicine at the 
Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania 

Associate Vice Chair for Faculty Development & Academic Affairs

Contact InformationHospital of the University of Pennsylvania
Department of Pathology and Laboratory Medicine
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104

Specialty Division

Anatomic Pathology

Research Expertise

Molecular and immunopathology of thyroid neoplasia

Clinical Expertise

Endocrine Pathology (Cytology and Histopathology)

Other Expertise

ENT Pathology

Cytopathology Expertise

Pulmonary Cytopathology


(Matriculation), Model School, Hyderabad, Pakistan, 1975
(Intermediate), Model College, Hyderabad, Pakistan, 1977
MBBS Liaquat Medical College, Jamshoro Sind Pakistan, 1985
MS Hahnemann University, Philadelphia, 1988
PhD Hahnemann University, Philadelphia, 1991

Specialty Certification

Anatomic and Clinical Pathology, American Board of Pathology, 1995
Subspecialty Certification in Cytopathology, American Board of Pathology, 1997

Postgraduate Training

Resident in Pathology, Hahnemann University, Philadelphia, PA, 1991-95
Chief Resident in Pathology, Hahnemann University, Philadelphia, PA, 1994-95
Fellow, Oncologic Surgical Pathology, Memorial Sloan-Kettering Cancer Center, 1995-96
Fellow, Cytopathology, Hospital of the University of Pennsylvania, 1996-97

Awards and Honors

Best Graduate, Liaquat Medical College, Pakistan, 1984
Dean’s List, Hahnemann University, Philadelphia, PA, 1990-91
Who's Who Among Graduate Students, 1991
Sigma Xi, 1994
Kevin Salhany Teaching Award, Department of Pathology and Laboratory Medicine,
University of Pennsylvania School of Medicine, 2009
Peter C. Nowell Teaching Award, Department of Pathology & Laboratory Medicine,
University of Pennsylvania School of Medicine, 2010
US News Top Doctors, 2011-18
America’s Top Doctors, Pathology, Castle Connolly, 2011-21
Mastership in Pathology Award, American Society of Clinical Pathology, 2014
President’s Award of Service, American Society of Clinical Pathology, 2015
Best Doctors in Pathology 2015-16, Suburban Life Magazine, 2015
The Power List 2018, The Pathologist Magazine, 2018
L. C. Tao Educator of The Year Award, Papanicolaou Society of Cytopathology, 2018-19
Top Doctor in Philadelphia, Philadelphia Magazine, 2018-23
H.P. Smith Award for Distinguished Pathology Educator, American Society of Clinical Pathology, 2020
Simon Flexner Award for Graduate Education, Department of Pathology & Laboratory Medicine,
Perelman School of Medicine at the University of Pennsylvania, 2021
Academy of Master Clinicians, Penn Medicine, 2022
President’s Award, American Society of Cytopathology, 2022

Memberships and Professional Organizations

Philadelphia Pathology Society, 1991-present
--- President, 2008-15

American Society of Clinical Pathology, 1995-present
---- Non-gynecologic Cytopathology Team Lead, Educational Committee, 2010-13
--- Chair, Scientific Program Committee, 2013
--- Clinical Competency and Professional Development Committee, 2017-20
--- NPQR Task Force, 2019-21

United States and Canadian Academy of Pathology, 1995-present
--- Education Committee, 2017-21

American Association for Clinical Endocrinologist, 1997-present

American Society of Cytopathology, 1997-present
--- Chair, Companion Society Committee, 2011-17
--- Executive Board, 2017-21
--- Chair, Annual Meeting Scientific Program Committee, 2021-23

American Thyroid Association, 1997-present
--- Laboratory Guidelines Committee, 2000-02
--- Annual Meeting Scientific Program Committee, 2014
--- Surgical Affairs Committee, 2014-15
--- Treatment Guidelines of Well-Differentiated Thyroid Carcinoma Committee, 2019-21

College of American Pathologists, 1997-present

Endocrine Pathology Society, 1997-present

Arthur Prudy Stout Society of Surgical Pathologists, 1999-present

Papanicolaou Society of Cytopathology, 2002-present
--- Director, Quality Assurance Committee, 2002-04
--- Director, Practice Guidelines & Quality Assurance Committee, 2005-09
--- Chair, Annual Scientific Program Committee, 2009-12
--- President-Elect, 2011-12
--- President, 2012-14

UPHS Clinical Trials and Scientific Review Committee, 2003-09

Endocrine Society, 2009-present

Hospital of the University of Pennsylvania Tissue Committee, 2009-present

Philadelphia Endocrine Society, 2010-present

Hospital of the University of Pennsylvania, Director of Cytopathology Fellowship Program, 2012-21

American Association of Clinical Endocrinologists, 2013-present
--- Ancillary Techniques Committee, 2013-15
--- Thyroid Nodule Task Force, 2016-20

UPHS Pathology Policy Integration Committee, 2013-15

Web Links

Selected Publications

Degenerative atypia in benign thyroid nodules: a potential diagnostic pitfall on fine-needle aspiration 

Lam H, Saoud C, Shi Q, Wong KS, Cibas ES, Rooper LM, Baloch Z, Ali SZ. J Am Soc Cytopathol 12(5):341-350, Sep-Oct 2023. PMID:37230891. 

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Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens

Andrianus S, Gubbiotti MA, Mandel SJ, Nikiforov YE, Baloch Z. Diagn Cytopathol 51(7): 406-413, Jul 2023. PMID:37042127.

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THADA-IGF2BP3 fusions detected in fine-needle aspiration specimens of thyroid nodules: An institutional experience

Gubbiotti MA, Andrianus S, Baloch Z. Diagn Cytopathol 51(6): 349-355, Jun 2023. PMID:36752652.

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Does the presence of capsule influence prognosis in poorly differentiated thyroid carcinoma?

Gubbiotti MA, Andrianus S, Sakhi R, Zhang Q, Montone K, Jalaly JB, Baloch Z. Hum Pathol 136: 96-104, Jun 2023. PMID:37054782.

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Carcinoma Ex Pleomorphic Adenomas: An Institutional Experience and Literature Review

Tondi-Resta I, Hobday SB, Gubbiotti MA, Jalaly JB, Rassekh CH, Montone KT, Baloch ZW. Am J Clin Pathol 159(5): 502-515, May 2023. PMID:36921078.

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Molecular Profiling of 50,734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management

Chiosea S, Hodak SP, Yip L, Abraham D, Baldwin C, Baloch Z, Gulec SA, Hannoush ZC, Haugen BR, Joseph L, Kargi AY, Khanafshar E, Livhits MJ, McIver B, Patel K, Patel SG, Randolph GW, Shaha AR, Sharma J, Stathatos N, van Zante A, Carty SE, Nikiforov YE, Nikiforova MN. J Clin Endocrinol Metab 18: dgad220, Apr 2023. PMID:37071871.

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DICER1 RNase IIIb domain mutations trigger widespread miRNA dysregulation and MAPK activation in pediatric thyroid cancer

Ricarte-Filho JC, Casado-Medrano V, Reichenberger E, Spangler Z, Scheerer M, Isaza A, Baran J, Patel T, MacFarland SP, Brodeur GM, Stewart DR, Baloch Z, Bauer AJ, Wasserman JD, Franco AT., Front Endocrinol (Lausanne) 14: 1083382, Feb 2023. PMID:36896180.

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Spindle cell variant of follicular thyroid carcinoma: An extremely unusual case and review of the literature

Pusztaszeri MP, Florianova L, Payne R, Baloch ZW. Diagn Cytopathol 50(11): E333-E338, Nov 2022. PMID:35866458.

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Making a case for the success of Milan system for reporting salivary gland cytopathology

Gubbiotti MA, Jalaly J, Baloch Z. Diagn Cytopathol 50(9): 451-455, Sep 2022. PMID:35801712.

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