Amrom Obstfeld, MD, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Assistant Director of Hematology and Coagulation Laboratories
Children's Hospital of Philadelphia
Contact InformationDepartment of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia
5th Floor Building - 5199C
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-426-7491
Fax: 215-590-1736
Education
B.A. (Biology, Asian and Middle Eastern Studies), University of Pennsylvania, 2003.
Ph.D. (Physiology), Columbia University, 2010.
M.D., College of Physicians and Surgeons, Columbia University, 2012.
Specialty Certification
American Board of Pathology, 2015
Postgraduate Training
Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 2012-2015
Certificate - Biomedical Informatics, University of Pennsylvania, 2019-2020
Awards and Honors
Magna Cum Laude, University of Pennsylvania, 2003
MD/PhD Symposium Award, Columbia University, 2007
Immunology Retreat 2nd Place Poster Prize, Columbia University, 2008
Student Research Day MD/PhD Award, Columbia University, 2010
Doctor Harold Lee Meierhof Memorial Prize for outstanding achievement in Pathology, Columbia University, 2012
The Leonard Berwick Residency Training Award, Perelman School of Medicine at the University of Pennsylvania, 2015
Penn Institute of Biomedical Informatics Junior Faculty Travel Award, 2016
Society of '67 Open Access Publication Award, Association of Pathology Chairs, 2020
Memberships and Professional Organizations
Association for Pathology Informatics, 2015 - Present
International Society for Laboratory Hematology, 2016 - Present
International Council for Standardization in Haematology, 2018 - Present
College of American Pathologists, 2018 - 2021
Harmonization Oversight Group, International Consortium for Harmonization of Clinical Laboratory Tests, 2019 - 2025
Joint Committee for Traceability in Laboratory Medicine, Blood Cell Counting and Typing Team, 2020 - Present
Web Links
Selected Publications
Reproducible Data Analysis With R in Laboratory Hematology
Obstfeld AE, Int J Lab Hematol 48(4): 757-764, 2026, PMID:42138489
Using R Statistical Programming to Evaluate the Impact of the Lower Anogenital Squamous Terminology Recommendations on Cervical Biopsy Reporting at a Tertiary Care Academic Center
Mehr CR, Obstfeld AE, Arch Pathol Lab Med, 2026, PMID:42320892
Practical Considerations in the Implementation of Peripheral Smear Review in the Clinical Laboratory
Pozdnyakova O, Yaeger LH, Shirai CL, McFadden S, Chen X, Obstfeld A, Mason EF, Ouseph MM, Han JY, Zini G, Hedley B, Grant M, D'Onofrio G, Frater JL, Courville EL, Int J Lab Hematol, 2026, PMID:42070993
Performance of Automated Hematology Analyzer Criteria in Detecting Peripheral Blood Smear Abnormalities: A Systematic Literature Review
Courville EL, Grant M, Mason E, Chen X, d'Onofrio G, Hedley B, Frater JL, Ouseph MM, Zini G, McFadden S, Han JY, Shirai C, Obstfeld A, Yaeger LH, Pozdnyakova O, Int J Lab Hematol, 2026, PMID:42115681
Diagnosis of platelet dysfunction in children: clinical predictors and test methods
Doshi BS, Thompson EN, Faig W, Wax A, Obstfeld AE, Lambert MP, Blood Vessel Thromb Hemost 3(1): 100135, 2026, PMID:41623363
Proceedings of the Association for Pathology Informatics Bootcamp 2023: Ethics, equity, and regulations
Stoffel MR, Obstfeld AE, Jackson BR, Azimi V, McCash SI, Arvisais-Anhalt S, Clifford LJ, Jackups R, J Pathol Inform 18(): 100452, 2025, PMID:40534902
A Multianalyte Machine Learning Model to Detect Wrong Blood in Complete Blood Count Tube Errors in a Pediatric Setting
Graham BV, Master SR, Obstfeld AE, Wilson RB, Clin Chem 71(3): 418-427, 2025, PMID:39797417
Retrieval-augmented generation versus document-grounded generation: a key distinction in large language models
Koga S, Ono D, Obstfeld A, J Pathol Clin Res 11(1): e70014, 2025, PMID:39817433
Reducing Erythrocyte Sedimentation Rate Ordering: De-implementation and Diagnostic Stewardship
Fatemi Y, Polsky T, Burns J, L'Etoile N, Obstfeld A, Zorc JJ, Nord E, Coffin S, Shaw K, Hosp Pediatr 14(8): 658-665, 2024, PMID:38988307
Report of the International Council for Standardization in Haematology working group for standardization of reticulocyte parameters
Obstfeld AE, Davis BH, Han JY, Urrechaga E, Int J Lab Hematol 46(2): 266-274, 2024, PMID:38054856
