Charuhas Deshpande, MD
Associate Professor of Clinical Pathology and Laboratory MedicinePerelman School of Medicine at the University of Pennsylvania
Contact InformationDepartment of Pathology and Laboratory Medicine
3400 Spruce Street, Founders - 6.039
Philadelphia, PA 19104-4283
Office: (215) 615-6523
Fax: (215) 349-5910
Email: charuhas.deshpande@pennmedicine.upenn.edu
Specialty Division
Anatomic Pathology
Research Expertise
Neoplastic and non-neoplastic diseases of lung, pleura and thymus.
Clinical Expertise
Pulmonary and Mediastinal Pathology,
Cardiovascular Pathology,
Education
MBBS Grant Medical College, Mumbai, India, 1986
MD (Pathology), Tata Memorial Hospital - University of Bombay, Mumbai, India, 1990
MD New York State Education Department, 2009
Specialty Certification
American Board of Pathology, 2008
Postgraduate Training
Resident - Pathology, Anatomic and Clinical, Tata Memorial Hospital, Mumbai, India, 1987-1990
Fellow in Surgical Oncopathology, Tata Memorial Hospital, Mumbai, India, 1991-1992
Research Associate, Rush Cancer Institute, Chicago, IL, 1998-2000
Research Associate, Northwestern University, Chicago, IL, 2000-2003
Resident in Pathology - Anatomic and Clinical, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2003-2004
Resident in Pathology - Anatomic and Clinical, Northwestern Memorial Hospital, Chicago, IL, 2004-2007
Chief Resident - Pathology, Anatomic and Clinical, Northwestern Memorial Hospital, Chicago IL, 2005-2006
Fellow in Oncologic Surgical Pathology, Memorial Sloan-Kettering Cancer Center, 2007-2008
Fellow in Thoracic Pathology, Memorial Sloan-Kettering Cancer Center, 2008-2009
Awards and Honors
The James E. Wheeler, MD Award For Excellence In Anatomic Pathology Resident Training, 2012
The Peter C. Nowell Teaching Award, 2013
Memberships and Professional Organizations
United States and Canadian Academy of Pathology, 2004 - Present
American Society of Clinical Pathologists, 2004 - Present
College of American Pathologists, 2004 - Present
Pulmonary Pathology Society, 2009 - Present
International Association for Study of Lung Cancer, 2010 - Present
Web Links
Selected Publications
Alpha-defensins: risk factor for thrombosis in COVID-19 infection.
Abdeen S, Bdeir K, Abu-Fanne R, Maraga E, Higazi M, Khurram N, Feldman M, Deshpande C, Litzky LA, Heyman SN, Montone KT, Cines DB, Higazi AA., British Journal of Haematology 194(1): 44-52, 2021, PMID:34053084
Molecular imaging can identify the location to perform a frozen biopsy during intraoperative frozen section consultation.
Bryski MG, Frenzel-Sulyok LG, Delikatny EJ, Deshpande C, Litzky LA, Singhal S., PLoS One 16(6): e0252731, 2021, PMID:34086790
Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity
Predina JD, Haas AR, Martinez M, O'Brien S, Moon EK, Woodruff P, Stadanlick J, Corbett C, Frenzel-Sulyok L, Bryski MG, Eruslanov E, Deshpande C, Langer C, Aguilar LK, Guzik BW, Manzanera AG, Aguilar-Cordova E, Singhal S, Albelda SM., Molecular Therapy 29(2): 658-670, 2021, PMID:33160076
Gene signature of antigen processing and presentation machinery predicts response to checkpoint blockade in non-small cell lung cancer (NSCLC) and melanoma
Thompson JC, Davis C, Deshpande C, Hwang WT, Jeffries S, Huang A, Mitchell TC, Langer CJ, Albelda SM., J Immunother Cancer. 8(2): e000974, 2020, PMID:33028693
Pembrolizumab After Completion of Locally Ablative Therapy for Oligometastatic Non-Small Cell Lung Cancer: A Phase 2 Trial.
Bauml JM, Mick R, Ciunci C, Aggarwal C, Davis C, Evans T, Deshpande C, Miller L, Patel P, Alley E, Knepley C, Mutale F, Cohen RB, Langer CJ., JAMA Oncology 1(2): 1283-1290, 2019, PMID:31294762
RB constrains lineage fidelity and multiple stages of tumour progression and metastasis.
Walter DM, Yates TJ, Ruiz-Torres M, Kim-Kiselak C, Gudiel AA, Deshpande C, Wang WZ, Cicchini M, Stokes KL, Tobias JW, Buza E, Feldser DM., Nature 569(7756): 423-427, 2019, PMID:31043741
A clinical trial of intraoperative near-infrared imaging to assess tumor extent and identify residual disease during anterior mediastinal tumor resection.
Predina JD, Keating J, Newton A, Corbett C, Xia L, Shin M, Frenzel Sulyok L, Deshpande C, Litzky L, Nie S, Kucharczuk JC, Singhal S., Cancer 125(5): 807-817, 2019, PMID:30561757
Localization of Pulmonary Ground-Glass Opacities with Folate Receptor-Targeted Intraoperative Molecular Imaging.
Predina JD, Newton A, Corbett C, Xia L, Sulyok LF, Shin M, Deshpande C, Litzky L, Barbosa E, Low PS, Kucharczuk JC, Singhal S, J Thorac Oncol. 13(7): 1028-1036, 2018, PMID:29626619
An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas.
Predina JD, Newton AD, Xia L, Corbett C, Connolly C, Shin M, Sulyok LF, Litzky L, Deshpande C, Nie S, Kularatne SA, Low PS, Singhal S., Oncotarget 9(17): 13517-13529, 2018, PMID:29568374
A Phase I Clinical Trial of Targeted Intraoperative Molecular Imaging for Pulmonary Adenocarcinomas.
Predina JD, Newton AD, Keating J, Dunbar A, Connolly C, Baldassari M, Mizelle J, Xia L, Deshpande C, Kucharczuk J, Low PS, Singhal S., Ann Thorac Surg. 105(3): 901-908, 2018, PMID:29397932
